Turing Machine
Bluelighter
- Joined
- Jun 16, 2010
- Messages
- 169
Cool, we're posting our grades now? What about IQ? What about Myers Briggs personality test results?
I wouldn't consider Meth a prodrug for amph since most meth is eliminated unchanged through the urine and is quite a bit more potent. It's been a long time since I've done either but IMO, the rush from insufflated meth is quite a bit more intense than even injected d-amphetamine. I don't know one way or the other but it wouldn't surprise me if d-meth had more serotinergic acitivity than d-amphetamine simply because it has more activity overall. Iirc in the case of MDMA, although the N-methylation lowers the potency, it does increase the ratio of serotinergic affinity in relation to catecholamines,
I wouldn't consider Meth a prodrug for amph since most meth is eliminated unchanged through the urine and is quite a bit more potent. It's been a long time since I've done either but IMO, the rush from insufflated meth is quite a bit more intense than even injected d-amphetamine. I don't know one way or the other but it wouldn't surprise me if d-meth had more serotinergic acitivity than d-amphetamine simply because it has more activity overall. Iirc in the case of MDMA, although the N-methylation lowers the potency, it does increase the ratio of serotinergic affinity in relation to catecholamines,