I often forget about DXO.
Makes me wonder what the ratios of DXM/DXO were inside me during different trips and how it impacted the trips.
They say DXO is more like ketamine while DXM is more delusion-inducing and visual. So 2D6 fast metabolizers will get more of the good part but I'm not so sure, since it will take some time to convert all into DXO and for me the good effects started instantly, as well as do now the acoustic hallucinations. I'd love to try DXO alone but it's difficult to imitate liver enzymes in vitro.
Never really looked at it that way (overdosing on SNRI), but I guess you're right. I wonder what kind of long term effects this would cause?
Well, it's more the NRI part as you can't overdose on a
selective SRI, a fluoxetine megadose of 120mg was exact the same as 40mg, just that it would allow more days before redosing. Just that no drug is really selective and there are off-targets which mediate the side effects. It's possible that DXM binds to other, unmentioned sites because they'd have checked regular dosages, max. 100mg, not overdoses for binding profile. Just Idk which receptor, kappa-opioid is very different too (salvia divinorum). It might be anticholinergic activity but when that was potent, it'd induce dry mouth before any hallucinations which it doesn't. Maybe selective for one subtype of mAChR's.
A buddy thinks that sigma is responsible for the psychotomimetic effects but I tried both selective sigmaergics pentoxyverine and noscapine, in massive overdose, and got no effects at all.
I've had some glorious times on DXM though. Maybe it was just cause I was delusional during the trip, but they some times felt very "magical" and felt like they had some kind of importance or meaning in my life. This feeling a lone could make some feel pretty damn good.
Then other times it was either very underwhelming (almost annoying) and then other times I would get really creepy side effects that felt like my body had a "ring of fire" circulating around it & I'd get a feeling of going up & down in an elevator in the top of my stomach and it would of course lead to me to panic attacks cause it would feel so bizarre. Not sure why this would happen on some trips and not others. Many times I thought "oh shit, I accidentally did it" (as in killed myself or injured an organ from doing too much).
Oh you're one of the first people to get the same or similar movement effects! My mind projects it into my legs and feet now but before it was in the stomach. Or when I'd lie down and close my eyes, listening to soft music I'd leave my body and float around freely. Did you try that? It's an incredible feeling.
Yeah, dissociatives can feel very magic. Idk if I learned anything from them besides to let go, but it were some of the most intense experiences in my life, almost religious.
They are safe unless seriously over-overdosed like over 1g of DXM, the arylcyclohexylamines are safer and just knock you out when overdone but it's pretty difficult to die from them. But I had the same moments of panic before I knew that it's just the threshold of full dissociation, when the connection to the body will be cut temporarily and thus no more feeling for breathing and heartbeat but the body takes care of them.
