Please! While loperamide can be very useful in helping you get through withdraws at moderate dosages, I implore eryone to please not use this at high dose for any period of time in an attempt to get high. I have done so taking 100 mg plus for several days together and it nearly killed me. My family found me unresponsive in bed. EMS had to be called my heart was shutting down and I nearly died. I ended up spending five days in the hospital with extremely high blood pressure have had tingling and numbness in my extremity since this occurred and doctors told me that I was very lucky as my heart was severely compromised.So please please do not use loperamide for recreational use.