Cocaine smells like fresh white painted room / gasoline / Ether
Methylphenidate (Ritalin) smells like nothing lol…..90% excipients/bulking/flow agents. (API is only 5-10% of tablet/capsule XR beads)
BOTH are nearly identical in their MOA, both being Inverse Agonist at DAT/NET/SERT
Methylphenidate (Ritalin) is actually close to twice as potent by weight at inhibiting DAT (ED-50) effective dose to inhibit 50% of dopamine transporters
Methylphenidate (Ritalin) DAT>NET (Dopamine 3-4X more than Norepinephrine)
Cocaine HCL DAT>SERT>NET (Dopamine & Serotonin prominent, Norepinephrine is lagging behind)
Both are excellent dopaminergic stimulant drugs….
Cocaine
Methylphenidate (Ritalin)
Phenmetrazine (apparently more desirable than I.V. Methamphetamine by users)
Biphetamine/Adderall
Amphetamine
d-Amphetamine
d-Methamphetamine
Dexamyl & Desbutal (Amph/Meth + Barbiturate)