A lot of drugs are pretty nasty. Generally it's going to be a relative thing... Some people can enjoy something that others find repulsive for instance.
Also, some things can become an acquired taste, whether through association or through desensitization from repeated exposure.
For example, my first cup of coffee tasted absolutely horrible. Nowadays my mouth waters at the thought of a freshly brewed cup of black coffee.
Same thing happened with a lot of drugs I've taken. Kratom was nasty, now I don't mind it so much. Same with mdma, dxm, and a plethora of others.
For me, however, some drugs never become better with repeated exposure, in fact some have become even harder for me to stomach over time. Examples of this would be tianeptine, Poppy pods tea, catcus brews etc.