I've been experiencing a lot of this for the past 5 months, since taking MDMA.
About Me
Just turned 30. Great job. Incredible fiancee. Financially stable. No drama in my life. Things are objectively, great. Recent years have been the best of my life. Do partner-dancing 1-2 times a week.
Previous Drug Experience
Only had alcohol/marijuana until I was 28.
Shrooms: 4 times. 3 of them were pretty mild experiences, just giggly/silly/childish/happy. 1 was a great trip I had at home that was pretty mind-altering.
MDMA: 1 time before this event (of which I'm writing this about), 6-7 months prior. Uncertain of the dosage, estimated ~100mg based on sight.
Acid: 2 months prior to this MDMA event. Had an absolutely terrifying experience. Was at a hippie-dance type camping trip in the woods, late at night. I don't think I've ever been so scared. Couldn't remember anything except for a 5-10second window prior to any given moment, including who I was, where I was, how I got there, etc. Was hazy/disoriented a bit for the the next week, but after that I felt fully-recovered.
My MDMA Event
Had about 20 of my closest friends over for a cuddle/mdma party on my 30th birthday. There were 10+ people that took the same batch, and they experienced no negative side effects. The night was great. Surrounded by friends, lovers, my partner (now fiancee) at home. I took ~100mg at 10pm. Bumped with 40-50mg (140-150mg total) around 1am. The night was phenomenal. Around 6am, everyone started falling asleep, and I recall having the thought "this was one of the best nights of my life, I'm not sure it will ever get any better than this. I wish it would last forever", but went to bed/sleep about 30minutes later.
The next day was fine, but somewhere around 48 hours, I went into a complete panic attack. I was certain that my death or my partner's death was right around the corner. I couldn't handle the thought of anything in the future because it was poisoned with fears of death and early mental decline. Other symptoms included: very depressed with feelings of hopelessness, extreme anxiety, memory loss such that I was having a hard time remembering what I did with my day at the end of the day (probably anxiety-induced), dysphoria when thinking about anything in the future, derealizatoin, depersonalization, vision blurry and having the effect of a video with really low frame-rate, feeling very floaty as if i had just "stood up too quickly" but was felt constantly, having loopy thoughts, difficulty reading, my face (especially my smile) felt really heavy, easily distracted and feeling mentally slow. I was basically having an ever-present panic attack that would last for the next 2-3 weeks. Thoughout that time I freaked myself out even more by reading things on the internet (like this forum), stressed myself and my partner out a LOT, and contemplated suicide every day (assuming that current mental state would not end). TONS of irrational fears and dysphoria regarding my relationships, work, future, etc.
After 10 days had passed, and the symptoms hadn't lessened, so I went to the ER with my partner. I told them everything I've told you so far. They were unable to prescribe me anything or help in any way. They attributed most of my symptoms to my anxiety. Around day 20, I was able to see a primary-care doctor who told me to give it more time to pass. At 1 the one month mark, he prescribed me Sertraline/Zoloft to try to "get me over this hump". After 1 month of no positive benefits and negative sexual-performance, he switched me to Wellbutrin/Bupropion @200mg/day. Also started psychotherapy at the same time, which was about 2.3months since the MDMA. Started to feel a little bit better in therapy, but not significantly. Increased wellbutrin to 300mg/day. After 3 weeks of that not being helpful, we switched to Duloxetine. Stopped that after about a week because it was giving me sexual side effects and making it very hard to get the energy to get out of bed.
I am writing this now at the 5 month mark, not feeling much difference between the 1 month mark and now. Just learning/relearning how to cope with my thoughts and mental state. Currently have been free of anti-depressants for a week, and at least my sex life is back to normal.
My Current State
I'm doing okay. Life is manageable. I organized a surprise proposal for my now-fiancee, work is decent, I'm learning how to manage my thoughts a bit more with Mindfulness Meditation. I feel a bit floaty, and about once a day I'll have an event where I feel very light-headed, and my thought process basically just freezes/resets, and I have to regather myself. Still more prone to anxiety than usual. Talking about how I feel actually amplifies those negative symptoms, so I try not to talk about it a whole lot. Life is still pretty great overall, the only symptom that's still unmanageable is derealization/dysphoria when thinking about the future and the value in life (my brain keeps telling me that there is none).
My Assessment Of Myself
I don't really have any solid answers as to what happened. Multiple doctors seem to think that the MDMA by itself shouldn't have effected me this much. They think it may have been some other mild mental disorder that I was perhaps prone to, which the weeks-long panic attack triggered. There's also thoughts that the acid 2 months prior could have been a factor since it was so terrifying for me. It's also possible that I've been having a sort-of midlife crisis, given that it happened on my 30th birthday. There's also the possibility that my mental state isn't actually much different, but that that traumatic experience made me more aware of who I've always been. Most of my friends, including my partner, didn't notice much of a difference in me, other than what I verbally communicated to them what I was feeling.
Recommendations For Anyone Going Through The Same Thing
Stop reading up on the internet about things that are going to scare you which may or may not even be true (some of the things I came across: brain damage, strokes, early parkinsons). The likelyhood of these things being your case are slim to none. That is a rational thought. Being convinced otherwise without an outside (doctor) source telling you that it is true is an irrational thought. Accept that pain, and trauma comes in various forms in life. This is no different. Learn how to manage your emotions and thoughts through whatever means works best for you (meditation, therapy, medicine if need-be). Fake it 'til you make it: pretend to be happier. Pretend that you're not so effected by what's going on, show that in your thoughts and body language. It's not lying to yourself, it's just setting yourself up for success and letting your brain rewire itself to the state that you want to be. You can trick your mind and body into being in states that you want it to be, the same as when you trick your mind into dysphoric thoughts because of your anxiety. It will improve, even if you don't get back to "normal", and you will learn to adapt, be happy, and go on with your life. Force those optimistic thoughts into your mind.