Misc Ketamine - is it OK to do it every day?

[Shant]

HERE IT IS CALL ME OUT BABY

That’s amazing. My key take away? Dude still does 5-10g a month. Which is mind boggling to me. I’m trying to find out if I can get away with 120mg a month (60mg IM, every 2 weeks). He insists, even with 5-10g a month, that his issues have mostly cleared up.

Im thinking frequency of use is a massive factor when it comes to permanent damage.

 

[Delmonte421]

I remember reading it as going WTF I am gonna follow this guys advice LMFAO

 

[Pissed_and_messed]

I was also significantly K'ed after minuscule line on on bupe

 

[Shant]

I reach hole territory somewhere between 175 and 300mg depending if it’s S isomer or racemic, tolerance and mental state. Everything over 350mg and experience would go from recreational to anesthetic experience within minutes.

Yeah that’s triple what I’ve been doing. Did you snort it?

Still would love to know the difference between a-isomer & racemic. Do they feel different? How do I know which one I have?

 

[Delmonte421]

im so fucking dumb when I do K cause im already fucked up so I just dump a fat line do it and see if it works, if it works I cant do another LOL but I got two kinds, one has nice sharp crystals and that isn't as portent as the one that looks more like cube chortle structure

I want the experts to tell me why the one crystal structure is so much better then the other one? IS it the chirality that changes the crystals or is one person drying it slower then the other to induce a better more structurally thermodynamically better crystal?

Weaker K
Better K

 

[nznity]

You’re making my point dude. I believe most people do it wrong. Snorting may be more convenient but good luck targeting a dose. You probably did too much or too little. It is ABSOLUTELY euphoric. And extremely empathogenic. Do it with a female friend and you’ll be hugging it cuddling the whole way. Do you really think I’d be doing it daily if it wasn’t amazing?

Ketamine has a very small dosage window. If I do 40mg IM, it feels like it never fully kicked in. If I do 80mg I’ll just lay there, maybe even fall asleep. But at 60mg IM, if it hits you the right way, it’s like nothing else you’ve ever tried.

I’ll put it this way. You ever do a drug that made you feel so good you literally smile and/or laugh the whole time? It’s super rare. I know I smiled after my first line of coke. MDMA maybe an hand full of times. Other than that, K is the only drug that has that effect on me. Roughly 1 out of every 5 trips.

I've done both small and high doses, I've never even snorted ketamine. I got access to pharma ketamine and I've only done IV/IM, but still no I don't like it. In fact, it's one of the few drugs that I've got fed up of it and thrown the rest of the vial I had to the garbage. If feeling dissociated, like looking at yourself from 3rd person euphoric for you. It's cool but I've done ketamine for over a decade many times and the conclusion is I don't like it. Xd

 

[ninjapirateroberts]

any and every drug everyday is a bad idea...the only one you can get away with everyday without too many issues, is weed

By weed, I assume you mean CBD, not THC? I think using THC daily seriously fucks up cognitive abilities (learning and memorization); I have been there and experienced it personally. But CBD is nice. I once had a cannabis cigarette that is 98% CBD and 2% THC, and I loved the relaxation effect it gave me. But these days I stick to CBD-only vapes.

 

[ninjapirateroberts]

Seconded.

There are people who develop serious addictions to Ketamine. It's not considered to be as addictive as Opioids. There are definitely niches of users who really gravitate toward the stuff though. I'm not as aware of the issues surrounding chronic Ketamine usage as I am concerning Opioids. I am aware of the connection between Ketamine and Bladder Damage. It seems to be pretty well-proven.

I watched a documentary featuring a British Ketamine Addict that many of you have probably also seen. This guy started using it in the Rave circuit. He developed a liking for it and when cameras found him, he had been a compulsive, daily user for ~5years or so. His use and compulsive behavior was no different to what you would see in a chronic Heroin user,

He was being seen medically to have a mesh screen installed to cover the areas in which his bladder was rupturing. At that stage, I believe he was already using catheters to urinate. All drugs have certain consequences. If you ask me, being forced to use catheters is a pretty serious consequence.

 

[ninjapirateroberts]

I didn’t do lines, I take exactly 60mg of the pure powder, intramuscular. Once in a day (before bed). But I don’t sleep on it. I stay up and either listen to music, watch a movie, or play video games. Absolutely enhances those experiences exponentially. I can honestly say I’ve never had a “bad trip” in all the times I’ve done it.

As for frequency, that’s what I’m trying to figure out. What would be a safe frequency at 60mg, IM?
Weekly? Bi-weekly? Monthly?

As for your last question, enantiomerically pure S-ketamine vs racemic…I’ve no idea what that means. How can I tell which it is, and what are the differences? All I can tell you is it’s a pure white powder.

You should ask your dealer. If you buy it from DNM, the vendor will advertise whether it's a racemic, R-ketamine, or S-ketamine. If you buy it elsewhere, ask the dealer. It's crucial to know whether you're taking S-K, R-K, or racemic.

 

[Delmonte421]

You should ask your dealer. If you buy it from DNM, the vendor will advertise whether it's a racemic, R-ketamine, or S-ketamine. If you buy it elsewhere, ask the dealer. It's crucial to know whether you're taking S-K, R-K, or racemic.

what's the difference, I mean I could google it but what's your personal experience on it?

 

[ninjapirateroberts]

what's the difference, I mean I could google it but what's your personal experience on it?

I think R-K is a less potent dissociative isomer. I tried neither racemic nor R-K; I only have experience with pharmaceutical-grade S-K powder.

Here's what Wikipedia says:

"Similarly to racemic ketamine and esketamine, the S(+) enantiomer of ketamine, arketamine [R-ketamine] is biologically active; however, it is less potent as an NMDA receptor antagonist and anesthetic and thus has never been approved or marketed for clinical use as an enantiopure drug."

Arketamine - Wikipedia

en.wikipedia.org

 

[Mr. Krinkle]

By weed, I assume you mean CBD, not THC? I think using THC daily seriously fucks up cognitive abilities (learning and memorization); I have been there and experienced it personally. But CBD is nice. I once had a cannabis cigarette that is 98% CBD and 2% THC, and I loved the relaxation effect it gave me. But these days I stick to CBD-only vapes.

No i mean weed

many people can get away with smoking weed everyday - maybe you just cant

 

[Delmonte421]

I don't know any real pot head that DONT smoke everyday

 

[AlsoTapered]

Their is much question as to the relative safety of MXE. As you might know it's not a ketamine metabolite but ketamine itself that causes the bladder damage. Now I would have thought that the m-mehoxy moiety would be deprotected and thus provide a simple, safe metabolic process...

But the papers I read suggest that O-demethylation isn't a major pathway. It's most certainly A pathway which is why I read what F&B wrote closely. F&B suggested swapping the O-Me for an O-Et which in most medicines, allows O-dealkylation to occur more readily. I don't think it was posited in such terms, but if it is indeed almost identical, than that would be a potentially a safer alternative.

As it is, the increased potency of MXE means people use less and so should theoretically reduce bladder damage. I mean MXE may cause lots of none at all. I cannot find data on that.

From a political perspective, NOBODY is ever going to say an RC is safer than a medicine. What I do know is that while Lifeline published a booklet on K-bladder syndrome, they haven't extended it to include MXE. I know the authors quite well and so while they hadn't enough data (at the time), I don't think they had come across MXE bladder damage.

But it IS true that their IS no such thing as a free lunch. People have mistakenly believed they could stop using K at any time... and could not. It's worth knowing what the risks are so that you can manage said risks.

Also using pins when one might already have ones mind someone altered by K isn't perfect.

Someone posted the horrific effects of K abuse and while it's 1 person, many other examples are known. It seems to be dose-dependent and we haven't isolated any further risk factors established.

 

[Shant]

I've done both small and high doses, I've never even snorted ketamine. I got access to pharma ketamine and I've only done IV/IM, but still no I don't like it. In fact, it's one of the few drugs that I've got fed up of it and thrown the rest of the vial I had to the garbage. If feeling dissociated, like looking at yourself from 3rd person euphoric for you. It's cool but I've done ketamine for over a decade many times and the conclusion is I don't like it. Xd

Fair enough brother, drugs do hit people in different ways. But when people say “it’s not euphoric” or “it’s not empathogenic”, I can’t help but think they missed the very narrow dosage window, which for me is 50-70mg. I split the difference and go 60mg, and it pretty much hits me the same way every time. I’ve noticed absolutely no tolerance, and stopping cold turkey 5 days ago hasn’t seemed to affected me in the least.

On another note, you actually shot it IV? That took some balls friend. Even doing it IM was a big hurdle for me. Even with 27 years of heroin, methadone, & fentanyl daily, I never once used a needle. But I’m convinced it’s the only way to go with K.

 

[Shant]

No i mean weed

many people can get away with smoking weed everyday - maybe you just cant

I’ve been smoking weed daily for about 15 years now. I know it’s anecdotal, but my memory is a shell if what it once was. When you’re high on weed, your short term memory is GONE. With THC’s absurdly long half life, why would anyone think the memory loss wouldn’t become permanent?

 

[Shant]

You should ask your dealer. If you buy it from DNM, the vendor will advertise whether it's a racemic, R-ketamine, or S-ketamine. If you buy it elsewhere, ask the dealer. It's crucial to know whether you're taking S-K, R-K, or racemic.

I guess I’ll have to ask him. I hope he actually knows. So, as far as you know, there is no physical distinction between them? In other words, they all look like standard white HCL powder? Thanks. Appreciate your depth of knowledge on this.

PS- DNM? Not familiar with this acronym.

 

[AlsoTapered]

Well I know people who regard IV as being the litmus test. 100% of it gets where it's going and FAST.

But pins all over are removing a stack of systems in your body designed to protect you from poisoning... so getting around all of those isn't great.
It isn't my job to tell you what is the best thing to do, but if you have all of the information then at least you can make an informed decision.

The examples we see tend to cover people who had access to such large quantities. I would certainly be interested in EXE (ethoxetamine) as F&B outlines. He's not a BLer to go into great depth... but he DOES give you all the information you need. In short - he knows but he's not about to spend days finding reference simply to prove what is evident.

BUT all of the information IS out there.

 

[ninjapirateroberts]

I guess I’ll have to ask him. I hope he actually knows. So, as far as you know, there is no physical distinction between them? In other words, they all look like standard white HCL powder? Thanks. Appreciate your depth of knowledge on this.

PS- DNM? Not familiar with this acronym.

I think they all look like standard white HCL powder, yes; DNM = dark net marketplace.

 

[AlsoTapered]

Ah, OK. Well the profits are no SO HUGE that vendors practice every trick in the book to rip people off.

We always got GC-MS/NMR and payment was escrow.

One Chinese group made the 4-Cl homologue of K. Only the NMR showed it wasn't K but a positional isomer... and STILL they argued the toss. NO, they couldn't explain the NMR... and suggested WE were wrong. But that was 25Kg that we did NOT buy.

That is the name of the game - avoiding rip-offs and trust me, every DAY they work out a new trick. NMR pretty much stops them all, but you have to spend £400 on doing it. I recommend it, but then I wasn't paying the £400.