Phenpsycho
Bluelighter
- Joined
- Nov 28, 2015
- Messages
- 122
Hi all~
So a specific topic that has been playing on my curiosity for awhile now is the chemistry/synthesis of triazolobenzos. While comparing the ridiculously exhaustive list of regular benzos to the list of them you see a huge gap in variances between the two. I've been trying to find an explanation all over the web but haven't been successful so i'm posting this thread to hopefully find an answer.
Is there a specific limitation to the synthesis of analogs in this new class that makes it impossible to create lam versions of all the pams? I know they've done it for clonazepam, flunitrazepam, oxazepam, flutoprazepam, flubromazepam etc. so why hasn't anybody made a version for example of diazepam or phenazepam, could it be they just wouldn't be very impressive or that it would be too costly to synthesize them?
Also when I was searching around the web I came across fluclorazolam:
It's still a theoretical molecule that hasn't been produced before and it seems strange to me that it hasn't considering how popular etizolam, clonazolam and the other RC triazolobenzos have become. Does anyone have any guesses about how highly the effects of it would rate?
If there is limitations to what can and can't be synthesized I would also be interested in hearing about what new ones could exist in the future.
So a specific topic that has been playing on my curiosity for awhile now is the chemistry/synthesis of triazolobenzos. While comparing the ridiculously exhaustive list of regular benzos to the list of them you see a huge gap in variances between the two. I've been trying to find an explanation all over the web but haven't been successful so i'm posting this thread to hopefully find an answer.
Is there a specific limitation to the synthesis of analogs in this new class that makes it impossible to create lam versions of all the pams? I know they've done it for clonazepam, flunitrazepam, oxazepam, flutoprazepam, flubromazepam etc. so why hasn't anybody made a version for example of diazepam or phenazepam, could it be they just wouldn't be very impressive or that it would be too costly to synthesize them?
Also when I was searching around the web I came across fluclorazolam:
It's still a theoretical molecule that hasn't been produced before and it seems strange to me that it hasn't considering how popular etizolam, clonazolam and the other RC triazolobenzos have become. Does anyone have any guesses about how highly the effects of it would rate?
If there is limitations to what can and can't be synthesized I would also be interested in hearing about what new ones could exist in the future.
Last edited: