Phenethylamines [Mescaline Subthread] Synthetic / Pure Mescaline - Dosage & Methods of Administration

[feedmesauce]

[Mescaline Subthread] Synthetic / Pure Mescaline - Dosage & Methods of Administration

[To the Big & Dandy Mescaline / Cacti Thread]


[original post:]

I'm not sure if anyone can answer my question due to the fact that Synthetic Mescaline is very rare. But does anyone know what times and doses to take mescaline at, erowid says like 300mg but should I take it all in one shot? Yes this is true, real, synthetic mescaline, but its yet to be lab tested. The vendor is extremely reliable so please don't tell me it is not real because I am almost positive that it is true. I am planning out my trip for sometime in the spring, by the mountains with a few of my local psyconauts . So if anyone knows the times and doses of synethic mescaline because I've looked around erowid and I couldn't fine any solid answers.

 

[Ismene]

Aldous Huxley, when he was a frail old man and had never tripped before in his life, took 400mg of synthetic mescaline and had a very gentle time. So if you're even the slightest experienced at tripping 300mg will barely get you past threshold.

Yes, you need to take 300mg all at once - breaking it up would mean you'd hardly feel anything. You'll probably not feel much anyway. 400-600mg would be a better starting dose depending on your experience.

 

[daytryptr]

Aldous Huxley, when he was a frail old man and had never tripped before in his life, took 400mg of synthetic mescaline and had a very gentle time. So if you're even the slightest experienced at tripping 300mg will barely get you past threshold.

Yes, you need to take 300mg all at once - breaking it up would mean you'd hardly feel anything. You'll probably not feel much anyway. 400-600mg would be a better starting dose depending on your experience.

Really?

300mg-400mg for me is a good medium-strong dose. 500mg is a high dose, i don't think i'd venture past 600mg, personally. Its physically safe to go higher, but i've heard reports of psychologically devastating mescaline expirences, and starting below/at a solid medium dose (250mg) is a smart thing to do. Mescaline is fun and easy at low/med doses, but take a large dose and it gets alot more complex than that.

You can have a bad trip on mescaline, even though everyone describes it as gentle, start low around 250mg for your first time. I'm kinda light (135lb), and thats a medium dose for me. 100mg is threshold for mescaline btw. 300mg, even for expirenced trippers is a good solid trip. But weight/tolerance factors into that as well.

If you want to trip hard your first time, then take more than a quarter gram. If not 250mg is a nice solid first time dose.

And be absolutely fucking sure its synthetic mescaline. If its anything else like a RC, amounts over 200mg are usually deadly for most of the shit passed of as synthetic mescaline (2c-x's, nbomes, mesc analouges, etc). Some of those would have to be cut with fillers to get the right dosage relative to a dose of mescaline to not arouse suspicition in those who know how potent mescaline is b/weight.

Also keep in mind, 500mg+ will most likely have you tripping for 14-20 hours. I've heard reports of 24 hour+, but that was from extracted and it could be from the other alkaloids.

BTW, all the dosages i listed in terms of my own expirence were from off white tannish fairly pure mescaline hcl & related alkaoids from bridgesii/pedro. I've never had synthetic mescaline.

 

[trip.more]

Doses are listed on erowid, not sure why you mention it's "synthetic". The only difference between extracted mescaline and mescaline made in a lab is a few other alkaloids are present. The doses are the same and I've never noticed any difference in effect. That being said I wouldn't take a mescaline sized dose right off the bat unless it's coming directly from a chemist. A lot of people pass things off as mescaline as it's illegal everywhere. Testing it would be a great idea.

Whether it's made in a lab or through biosynthesis does not change the dose or anything else.

 

[amanitadine]

HCl or sulfate? If it is sulfate you won't be satisfied with less than 400. Or at least I wasn't. 500 is where it gets really interesting for the sulfate, 400 for the HCl. I find that once you reach activity mescaline dose/effects ratio has a somewhat steeper response curve than linear. . . .

 

[Ismene]

Really?

Yeah, Aldous was 60 at the time and had never taken a drug before in his life. 400mg was pretty comfortable for him.

So if you're used to tripping I can't see 400mg of mescaline doing too much for you.

 

[champ]

if it's sulfate, take 400 or more. I found 500mg to even be somewhat moderate in terms of intensity. However, mescaline is not some kind of knock you over the head overwhelming material--it lives up to its reputation as a "gentle teacher"

 

[Solipsis]

Twice I have taken synthetic mescaline, both times the dose was broken up in 3 parts to be more easy on the stomach, spaced only 15-20 minutes though.
The first time it was 330 mg and the second time I took over 450 mg.

In terms of psychedelia I found the 330 mg to be quite weak, but it was very empathogenic like a full on MDMA therapy session. The second time there still wasn't much typical trippiness or open eye visuals, but the closed eye visions were pretty seriously intense and the body load was significant.
I may go higher some time but not by much, if I would opt for a bigger psychedelic component I would combine with a quantity of LSD or something like synthetic psilocin. I don't always think combining a PEA with a trypamine is where it's at but not underestimating the physical load of mescaline I would like anything added to be much lighter like a 4-HO tryptamine.

Like any first time though, I recommend not combining at all. Mescaline might not be a typical wacked out trip like for instance LSD, but it is a special experience and I think the spiritual significance and potential for transformation should be allowed to flow unimpeded and uncomplicated.

Best wishes on your journeys.

 

[Ismene]

I don't see the relevance of his age and physical frailty - mescaline is a mind thing

It was his first trip tho. Having a big IQ doesn't make much difference to your first trip.

400mg is a good, solid dose. 500-600 is where you're going into 12+ hour ++++ territory

I don't think another 100-200mg makes that much difference.

 

[daytryptr]

Twice I have taken synthetic mescaline, both times the dose was broken up in 3 parts to be more easy on the stomach, spaced only 15-20 minutes though.
The first time it was 330 mg and the second time I took over 450 mg.

In terms of psychedelia I found the 330 mg to be quite weak, but it was very empathogenic like a full on MDMA therapy session. The second time there still wasn't much typical trippiness or open eye visuals, but the closed eye visions were pretty seriously intense and the body load was significant.
I may go higher some time but not by much, if I would opt for a bigger psychedelic component I would combine with a quantity of LSD or something like synthetic psilocin. I don't always think combining a PEA with a trypamine is where it's at but not underestimating the physical load of mescaline I would like anything added to be much lighter like a 4-HO tryptamine.

Like any first time though, I recommend not combining at all. Mescaline might not be a typical wacked out trip like for instance LSD, but it is a special experience and I think the spiritual significance and potential for transformation should be allowed to flow unimpeded and uncomplicated.

Best wishes on your journeys.

lower dosaged of mescaline and 4-ho tryptamines are indeed a wonderful combo in my expirence. definately worth looking into if you feel comfortabe with both substances. lsd and mescaline in low doses was pretty nice too. still mescaline by itself is just as revered in my book, if not more.

and dosage reccomendations are going to be all over the place, as you have the sulfate and hcl, extracted from a fairy good number of different cacti. all with different alk profiles, sometimes very different. then you have tolerance/expirence with psychs, along with bodychemistry and weight.

OP, imho just find out what salt it is, factor in your weight and tolerance/expirence w/ psychs, think about how high you want to dose and go off the erowid chart. i think anecdotal advice will be all over the place due to salt weigt differences, body weight, tolerance, and a whole ton of other factors.

 

[amanitadine]

It was his first trip tho. Having a big IQ doesn't make much difference to your first trip.

400mg is a good, solid dose. 500-600 is where you're going into 12+ hour ++++ territory

I don't think another 100-200mg makes that much difference.

Ismene I agree with a damn near 99% of your posts but I might have to split hairs on this one. As I stated above, mescaline is dullsville (albeit still worthy) until real activity is reached (400mg) but the dose response curve gets steeper IME as you climb from there on out. It's always manageable, to an experienced tripper, but 680 mg of HCl was incredibly strong, almost overwhelming, and just as beautiful. Mescaline makes me kinda sleepy and laconic until the higher doses, and then becomes increasingly stimulating. Fab stuff!

Oh and splitting the dose does make nausea less but also has diminished returns in terms of intensity. I dissolve in juice and drink in under ten mins or less.

 

[Ismene]

until real activity is reached (400mg) but the dose response curve gets steeper IME as you climb from there on out.

Do you find it approaches the power of a high dose acid or mushroom trip tho amanitadine? I was always slightly underwhelmed by how psychedelic it was - beautiful drug but it didn't really get anywhere near as psychedelic as mushrooms or acid. I was never quite sure how high the dose I was taking was but it was an extraction from about 250g of dried cactus chips from a guy in Peru. Always still found it very manageable although I do have a very high tolerance, more so for psilocybin than LSD.

And it being his first trip would be more relevant than his age; I was just saying that his being "old and frail" had no impact whatsoever on his ability to manage a trip.

Yeah I get your point ponti, I just thought it might be a bit harder for a 60 year old to deal with a heavy trip. Perhaps it doesn't work like that and it does depend more on the persons mindset.

 

[feedmesauce]

Yea I think I'm gunna stick with what I planned on. 300mg taken in one dose. But first, off to the lab to make sure I'm not taking an RC, will report back even though I'm almost positive its real.

 

[Ismene]

+200mg means a 50% increase in alkaloid.

True, but if 400mg can be handled pretty well by a 60 year old man on his first trip..I think if you've been doing heavy acid trips for 20 years, a dose that an old man on his first trip can handle with ease isn't going to turn you into a glass of orange juice. I think you could cope with an extra 200mg than Aldous.

I've gone upwards of a gram of mescaline and still found it very gentle and lightly psychedelic. Certainly nowhere even remotely comparable to a high dose of acid or mushrooms.

 

[Solipsis]

You know, psychedelia isn't the only factor to take into account. Like I said even at my higher dose (450 mg but it was the HCl) the amount of typical trippiness was well under control, I was not in the least confused, disoriented or mindfucked by mental cross-wiring. However the body load wasn't something I would care to push considerably higher - well maybe a bit - and the feeling of spiritual transformation felt definitely well developed. Maybe the question is whether you want to use mescaline for an experience of beauty and insight into matters of the heart, or... if you want to push beyond that and try to get that trippiness out (on top of it).

I'm not surprised you didn't even feel like it compared to serious all-round psychedelics at over a gram, apparently it just doesn't have the same kind of potential. I think you can treasure it for what it is, instead of checking how far you can go with it to see if it's something maybe it's just not.

I kind of find it hard to explain exactly what I would expect to be more intense in a worthwhile way if I were to significantly up my dose. Not that I mean to say I am not interested in finding out some day. It's just harder and less obvious than with other typical psychedelics.

Actually it seems kind of strange to me to call it a classical psychedelic, if it wasn't for the historical use by way of cacti.

 

[amanitadine]

Do you find it approaches the power of a high dose acid or mushroom trip tho amanitadine? I was always slightly underwhelmed by how psychedelic it was - beautiful drug but it didn't really get anywhere near as psychedelic as mushrooms or acid. I was never quite sure how high the dose I was taking was but it was an extraction from about 250g of dried cactus chips from a guy in Peru. Always still found it very manageable although I do have a very high tolerance, more so for psilocybin than LSD.

My 680 HCl trip was astoundingly intense, but you are correct in that it didn't mimic or approach the intensity of high dose LSD or mushrooms. Being a substrate for MAO I think when the dose is that high enough of the MAO is being utilized that perhaps a slight cascade effect is at play. Mescaline is in a league of it's own, far more psychedelic than say 2C-B , but as Sol points out it has an amazing "spiritual" component to it that I have yet to find in any other substance. It does get pretty intense in the high doses, but I always felt I could push it further, "body load" included. It gets strangely stimulating at these high doses, where as at below 4-500 mg I am content to just lay in bed.

FWIW I found the cactus extractions quite different from synthetic mescaline. Not as crystalline, "warmer", and about 80% as "psychedelic", for whatever reason. My guess would be the extract is like 80% mescaline and the rest a mixture of different alkaloids, lending it the less refined flavor.

Cheers

 

[Ismene]

I think there's only 6 or 7 other alkaloids in san pedro - not sure how many of them are active or have any effect so mescaline is the pretty much the only one you'd feel. Peyote has about 60 other alkaloids so there might be more of a difference with that.

Interesting about the MAOI tho - I wonder what it breaks the mescaline down to. MAOI work incredibly well with mushrooms but they don't seem to do much to LSD, in fact the only time I ever tried LSD with moclobemide it seemed to kill the trip.

 

[PARACAPS]

What is the best way to consume Mescaline HCI

I've had it before in a capsule but I was wondering if it would be better to dissolve in it juice/water ?

I'm still undecided on the dosage as I had a very magical experience the last time (many years ago) but I wasn't advised on the dosage.
I'm leaning towards 400mg but I don't want it to be too heavy/intense.
Judging by the comments posted/research it seems like 400mg is a safe bet.

 

[Solipsis]

It's mescaline HCL but the L is not a capital letter. So HCl.

And it should not matter too much whether you take it in a capsule or dissolved, although in a solution in juice or water it can have a slightly stronger impact but it can also be slightly more offensive to the stomach most of all because you are more aware of the drug being ingested because you taste it and you can get psychosomatic effects.

Personally I have taken mescaline (as the HCl as well) both in capsules as well as dissolved in water and honestly it did not differ *that* much, but more importantly I staggered the dose by dividing it into 3 portions and leaving about 15-20 minutes between them.
I chose that timeframe because if you leave too long then if you throw up after an hour you might lose some of your dose. If you leave less time, then it doesn't really have a point.

Have a safe journey

 

[Spacemonkey5000]

True, but if 400mg can be handled pretty well by a 60 year old man on his first trip..I think if you've been doing heavy acid trips for 20 years, a dose that an old man on his first trip can handle with ease isn't going to turn you into a glass of orange juice. I think you could cope with an extra 200mg than Aldous.

I've gone upwards of a gram of mescaline and still found it very gentle and lightly psychedelic. Certainly nowhere even remotely comparable to a high dose of acid or mushrooms.

This intrigues me but further increases my thesis that mescalito is a living entity and chooses when he wants to visit you, confused??? thats ok im gonna explain it.


I cant say that i know what this is about but i can tell you that i grow san pedro and have gotten a very deep relationsship with them.

Ive eaten cacti about 7 times or so, 2-3light ones a couple of solid +++ ones and 2 real profound all out ++++ trips...




I wont go to much in detail inless someone asks but in short you can say that i started out with one light trip (30g dry skin +3g rue) which was nice but had a very serious tone with it reminded me of mama aya...


The second one was a +++ with some ++++ elements in there, i killed a 3feet very skinny san pedro (very wrong of me) me and a friend split like 3/4 of it and tripped bawlz all night def one of my deepest trips ever, it was hard though, like a strong dose of aya but with a male vibe, powerful oev´s like 200mcg acid but very different.



After that i had 2 more profound plain cacti journeys, one bad one when i did 150mcgo lsd cause the cacti was weaker than i thought, one really special with the last part from the second trip plus some shrooms and caapi tea.




My point is mescaline is Beez kneez, idk why your mesc aint working but my san pedro does the trick, check out a good source for fresh cuttings, make sure its a potent clone and start with 1foot.

Ive had very strong trips from 1foot of good pedro.


Also mesc + shrooms is very very nice, no added bodyload imo, also i only get mesc body load in the comeup.



And sorry for writing like i mong, im really high %)