Interesting study pyth. I suppose I should've said "released at death in quantities large enough to make you trip balls". It would be useful to know if this is what happens to most things in the brain when you go into cardiac arrest or if it's unique to DMT and whether the concentration of DMT varies over the day in response to sleep, stress, exercise etc.I mean, Strassman was blowing it out of his ass in true classic wishful-thinking psychedelic mythologizing fashion, but I guess he got sort of lucky
Here's the study, but it's only one, and the usual caveats apply:
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain...www.nature.com
Must admit I find it hard seeing how a pineal gland about the size of a grain of rice can instantly produce 10-50mg of DMT - multiple times it's own weight. And I've never read an NDE that sounded like a DMT trip either.
Be interesting to find out where this idea "DMT makes you feel like you''re dying dude" came from. I've taken an absolute shitload of DMT but I usually take it orally - never felt I was "dying" once. Not ever remotely close. Felt absolutely on top of the world, at my absolute peak and buzzing with the thrill of life. Maybe if I was taking it in a room with a bunch of teenage mates smoking it and everyone saying "Dude you'll feel like you are dying". Then perhaps smoking it with that in your ears creates the experience of "Dude,where's my car? I'm dying".