It's a dangerous combination. 25i killed a lot of people by itself. Combining it with something like aMT is just asking for trouble.
As Headphone said 25i itself is decently dangerous. And aMT also does not come with the safest profile.
AFAIK combining aMT with 25i is safer than taking 25i alone, as it is the extreme selectivity for 5HT2A receptor that causes the clotting that has apparently been the cause of the deaths from 25i.
Using aMT you get stimulation at several other 5HT receptors including 5HT2C which counters the dangers of selective high affinity 5HT2A receptor agonists like 25i.
aMT is dangerous in overdose territory (like all triple releasers are) and when in combination with other Serotonine releasers.
25i is not a serotonin releaser and combining with aMT never caused anything resembling or even approaching serotonin syndrome such as markedly increased temperature.
In high dosages the MAOI action of aMT adds to the risks ofcourse but that is only in high dosages and is dependent on the person and their current tolerance.
Ofcourse I am not recommending anyone tries this combo and if they want to do it they should first experiment with each compound separately and try low dosages of the combo first.
Without a tolerance, 100mg of Ketamine, 25mg of aMT and 0.4mg of insufflated 25i are a very visual experience that will probably be between ++ and +++, and I would advise to not exceed double that dose especially if you do not have a sober tripsitter and are far from an ER.
Ofcourse take this with as many grains of salt as you need and it is only my personal experience combined with a few friend's.