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The Big & Dandy 4-PropO-DiPT Thread

planckunit

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dilated pupil said:
I received one gram of this substance today.
What would be a save dose to start testing with?
First I would try to confirm if your substance is "4-propionyl-N,N-diisopropyltryptamine" as <pyridinyl_30> suggested or "4-propionyloxy-N,N-diisopropyltryptamine". If it is the latter, start very low, but it will probably turn out to be be like AcO-DiPT in almost every way I guess. If it is the first: the effects could be totally unpredictable and I would proceed very carefully.
 

Jabberwocky

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Riemann Zeta said:
You could certainly do an ultra-low dose just to confirm the safety (well, more to confirm the authenticity of the material). After that, I doubt it would be more potent than 4-OH-DiPT, which I found amazing (but super short acting) at 25-30mg, so that's probably where I'd begin after testing for idiosyncratic reactions.
i would suggest scaling it up more in the manner of a more unknown chem (rather than one related to a known chem). Every chemical is unique...we still don't know the biosynthetic pathways completely for most of these chems...this chemical could be a curveball in our understanding.
 

dilated pupil

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The substance is 4-propionyl-N,N-diisopropyltryptamine so I followed planckunits advice and started carefully by ingesting 2 mg this evening.
Within 15 minutes I started to feel a little bit lightheaded (most likely placebo).
The lightheadedness went away after a few minutes and nothing else was felt.
Luckily I didnt't felt any idiosyncratic reactions either.
So tomorrow or in the weekend I will try 5 mg or more.
 

nuke

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I'm pretty sure this substance is the propionate/propanoate ester (the synth is much more straightforward and obvious). Same thing as 4-propionyl, propionyl just isn't used very much. For instance, the propanoate ester of l-carnitine is propionyl-l-carnitine.
 
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dilated pupil

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Ingested 5 mg today.
Felt a kind of restlessness within 30 minutes after ingestion and very mild stimulation.
But it was not even a +1 on the Shulgin scale.

I haven't tried 4-aco-dipt or 4-ho-dipt so I can't compare any of the effects but it seems to me that the active dose is in the same range.
But I continue to test as safe as possible.
Next weekend: 10mg
 
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dilated pupil

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I got home from work real early and I'm not able to test 4-pro next weekend (going to iron maiden on saterday that means a hangover on sunday :| ) so I tought why not take it now.
I measured 12mg at 15.00 and went to the grocery store, when I walked in at 15.15 I noticed the first effects and was constantly distracted.
On the way back home I started to get a bit nausea and noticed that the my sight was slightly altered (intence colors) and sound sounded a bit distant.
When I walked into my appartment I noticed my tongue and fingers felt a bit rubberish.
At 15.30 I lain down on the couch (I wasn't nausea anymore) and started staring at the clouds wich seems to morph into each other a bit.
My tought patterns where affected and started thinking about that I have no reason to complain about my current life but I'm doing it a lot anyway, so I decided to quit doing that starting right now.
At a certain moment I stared at the ceiling for a while and then I started to see some patterning but it never got really psychedelic but it will be at 20 mg for sure!=D
At 16.50 I was back at baseline.

The 'trip' felt like the comedown of a great mushroom trip but with a nice warm body high (especially in the legs) and a clearer mind.
It also felt really 'clean' after the nausea was gone.

Strange enough I didn't find it stimulating at this dose at 5 mg I thought it was but it was probably placebo.
I didnt't expected these effects with this dose, looks like 1+1=3 with this drug compared with the 5 mg 'experience'.

Can't wait for the 15 or 20mg experience but I'm a bit busy the next week.:\
patience patience......
 
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Iodjini_dk

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Have heard from others that the dosage should be 15-30 mg. The effects last 10-16 hours in general and the experience should be somewhat similar to 4-AcO-DiPT. I haven't tried it myself however. Maybe sometime in the future. It's quite expensive where I live for some reason.
 
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nuke

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If the effects last that long it could make for a very neat long-lasting DMT analogue. We'll see when more reports roll in, I guess.
 

dread

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4-propanoyl-dipt should metabolize to 4-ho-dipt, just like 4-aco-dipt does. So I'm guessing that the effects would not be very different.
 

nuke

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It's more lipophilic so more may get past the BBB, and in the event that it must undergo metabolism to become active, at a dose of 15-30mg it may produce longer effects because of a drawn out metabolism. Certainly the 4-AcO's last longer in me.

But, we'll see.
 

Jabberwocky

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^ thats true but I always just thought that was because of their latency in onset/smoother onset? (they take like 30-45 minutes to really get going and 4-HO's take like 10-15)
 

nuke

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It's the (faux) oral rule of pharmacokinetics: speedy in, speedy out, slowly in, slowly out (you'll notice pretty much everything in PiHKAL/TiHKAL with a long duration has a slow oral comeup). That is, a compound with longer duration usually takes longer to reach peak plasma levels than a compound with shorter duration. The 4-HOs usually take 45 minutes to peak for me though, and the AcOs take an hour.
 
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