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The Big and Dandy 3-MeO-2-oxo-PCPr (MXPr) Thread

Lashtamine

Greenlighter
Joined
Oct 12, 2019
Messages
8
I don't get what you mean about anyone would be disappointed either by my approach, this is being referred to as a potential MXE replacement, 160mg of MXE IM'd would be fantastic for me this was not which is what's disappointing here.
It may be referred to as a potential MXE replacement, but it is a unique compound despite its close structural similarity to MXE and it should be treated as such. You shouldn't dive into it expecting it to line up in any way to the effects of MXE as it very likely will have its own unique dose response curve and may be more or less potent than MXE and it may very well carry some unique effects that MXE lacks. What I'm trying to say is that you would be better off starting at a very low dose and working your way up, gauging your response as you titrate the dose up slowly to get a feel for how this compound effects you, ignoring any preconceived notions as to how it should affect you and treating it as an entirely new compound with its own unique effect profile. It may be very close to MXE structurally, but replacing an ethyl group with a propyl can change a lot about how a compound binds to receptors in the brain and it should thus be treated as a unique drug, rather than trying to infer doses and effects based off its relation to other compounds as trying to guess the effects of a drug based on structure activity relationship is notoriously unreliable.

Sorry if I come across as preachy but this is just how I go about sampling new compounds as it seems to be the safest way to understand the effects of a novel compound.
 
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pandahaze

Bluelighter
Joined
Dec 10, 2012
Messages
133
This trip report is exactly how I was feeling on MXE. I think we just need to try it and see how we feel, because this is definitely one of the chems that it's perfect for you or not.
 

Funkadelica

Bluelighter
Joined
May 16, 2013
Messages
669
So, now had two experiences with MXPr. I loved MXE, was up there as one of my favourites. The revelations, insights, and visions were unparalleled by any other drug for me and that amazing afterglow you had for days and days was magical. Sadly, the ban happened and that was that for me with it and other dissociatives, including S-Ketamine which ran MXE close. It's been over 3 years then since I touched any kind of disso's. So my receptors were nice and fresh yesterday.

I decided to go for the nasal route as my standard form of taking these, so just as as I did with my very first MXE line I insufflated 30mg's. Hit me like a freight train and holed at the peak, just like my very first MXE line at 30mg's. It was like visiting an old friend, yet a lot was different. No real insights, euphoria, or positivity. Just kind of empty, shallow and way more sedating. Couldn't open my eyes. It definitely lasts longer too but there was no afterglow or lift of depression (not that I have any) but just emptiness. I was so disappointed.

Felt really off this morning, kind of down in the dumps and soulless. It was around midday that it dawned on me that only few hours prior to sampling yesterday I had had an energy drink with 200mg of caffeine and then a really intense workout. I absolutely forgot that caffeine and MXE did not mix well for me. I always found MXE to be weird that way in that anything can influence its effects. Certain types of foods, sugar and spices even. It seems the same can be said for this one too.

I was always going to keep up experimenting so today measured 35mg. Much, much better. Very reminiscent of MXE this time, but I didn't manage to hole even with a 15mg top up after 15 minutes. Redosing never really did it for me on MXE either. I always preferred to get to where I wanted to be and then leave it till another time. However, this time it really was like visiting an old friend. It was very pleasurable; warm, glowing, smiley, stretching was amazing (used to love doing yoga on MXE), music was amazing and had that old MXE psychedelia and depth to it (I always find spacey downtempo/electronic/lounge/trip-hop to be ideal for these, like Tycho, Bonobo, Cinematic Orchestra etc), and I managed to get a bit of minor introspection which was greatly appreciated. And now I feel pretty good afterwards.

For those that really loved MXE I firmly believe you'll enjoy MXPr, especially if you enjoy it for what it is. They are very similar. I used to use MXE as a tool but I see (early days though) this one being used more for recreation, and that's fine. Next time I'll up the dosage and see where that takes me. I'm also now going to try and stop comparing to MXE as it has something to offer on its own and there's great potential with this one.
 

Kodeisko

Bluelighter
Joined
Aug 12, 2019
Messages
26
So, now had two experiences with MXPr. I loved MXE, was up there as one of my favourites. The revelations, insights, and visions were unparalleled by any other drug for me and that amazing afterglow you had for days and days was magical. Sadly, the ban happened and that was that for me with it and other dissociatives, including S-Ketamine which ran MXE close. It's been over 3 years then since I touched any kind of disso's. So my receptors were nice and fresh yesterday.

I decided to go for the nasal route as my standard form of taking these, so just as as I did with my very first MXE line I insufflated 30mg's. Hit me like a freight train and holed at the peak, just like my very first MXE line at 30mg's. It was like visiting an old friend, yet a lot was different. No real insights, euphoria, or positivity. Just kind of empty, shallow and way more sedating. Couldn't open my eyes. It definitely lasts longer too but there was no afterglow or lift of depression (not that I have any) but just emptiness. I was so disappointed.

Felt really off this morning, kind of down in the dumps and soulless. It was around midday that it dawned on me that only few hours prior to sampling yesterday I had had an energy drink with 200mg of caffeine and then a really intense workout. I absolutely forgot that caffeine and MXE did not mix well for me. I always found MXE to be weird that way in that anything can influence its effects. Certain types of foods, sugar and spices even. It seems the same can be said for this one too.

I was always going to keep up experimenting so today measured 35mg. Much, much better. Very reminiscent of MXE this time, but I didn't manage to hole even with a 15mg top up after 15 minutes. Redosing never really did it for me on MXE either. I always preferred to get to where I wanted to be and then leave it till another time. However, this time it really was like visiting an old friend. It was very pleasurable; warm, glowing, smiley, stretching was amazing (used to love doing yoga on MXE), music was amazing and had that old MXE psychedelia and depth to it (I always find spacey downtempo/electronic/lounge/trip-hop to be ideal for these, like Tycho, Bonobo, Cinematic Orchestra etc), and I managed to get a bit of minor introspection which was greatly appreciated. And now I feel pretty good afterwards.

For those that really loved MXE I firmly believe you'll enjoy MXPr, especially if you enjoy it for what it is. They are very similar. I used to use MXE as a tool but I see (early days though) this one being used more for recreation, and that's fine. Next time I'll up the dosage and see where that takes me. I'm also now going to try and stop comparing to MXE as it has something to offer on its own and there's great potential with this one.
Thanks for the report, as insufflation is also my route for dissos i enjoy this a lot.
What about the taste ? MXE had the best taste on earth imo.
Also, can i quote your report on r/Researchchemicals from Reddit for all people with eyes turned on MXPr if you haven't planned it yet ?
 

Funkadelica

Bluelighter
Joined
May 16, 2013
Messages
669
Yes, it absolutely does have that exact same distinct sense of smell and taste that you have when it hits you. I had totally forgotten about that strange taste and it was the first thing that I noticed and was like 'oh yeah this is much like MXE' when I was coming up for the first time yesterday. The powder is a little bit clumpy and burns a little, but as long as you wet your nostril before it'll be fine. Well it was for me today anyway compared to yesterday.

And yeah go for it, I don't have an account on there but happy to share the experience!
 

Kodeisko

Bluelighter
Joined
Aug 12, 2019
Messages
26
Nice ! 👃
Oh and what do you think about the addictive potential ? I would avoid redosing abuse like with MXE, maybe compulsive redosing is more common with insufflation than sub/oral/plug idk
 

Cream Gravy?

Moderator: DC, F&TV, PD
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Jan 28, 2014
Messages
8,826
MXE had the best taste on earth imo.
Yeah lol, I love the drip of MXE. Snooting it is probably in my top ten activities in life. The taste is almost... sweet, for lack of a better term. Always felt like MXE helped me to commune with the spirit world.

Want to try this new disso badly now >.<
 

Funkadelica

Bluelighter
Joined
May 16, 2013
Messages
669
Nice ! 👃
Oh and what do you think about the addictive potential ? I would avoid redosing abuse like with MXE, maybe compulsive redosing is more common with insufflation than sub/oral/plug idk
Hard to say at this stage but I would say MXE was definitely more morish. I had the inclination to do a bit more but easily persuaded myself to wait until the weekend to have a proper bash. That being said, I have had thoughts this morning about giving it a shot again tonight but I really will not be able to so. I guess the more frequent you do it then you'll have the urges.

I should also point out that, despite being able to fall asleep easily on it, I have experienced both nights a disturbed, broken sleep where I woke up at 3am and couldn't sleep for hours after. This was even 6 hours dosing before going to bed so there is some sort of effect going on still that disturbs sleep. I suppose in a way this is a good thing so I keep it strictly for weekend purposes.
 

Xorkoth

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I find that dissos in general disturb my sleep, never found one that doesn't, no matter how sedating.
 

Cream Gravy?

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Indeed. Upon ingestion, I never tried to sleep after MXE until at least 6 hours had passed.
 

Kodeisko

Bluelighter
Joined
Aug 12, 2019
Messages
26
True, strange fact, want to know which process is involved from dissos to make sleep impossible during the main & residual dissociation
 

TrippyZebra

Greenlighter
Joined
Jan 31, 2016
Messages
35
I'm definitely watching this thread never tried mxe but IM k has been my favorite substance for quite some time. Interested in hearing more reports.
 
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Cream Gravy?

Moderator: DC, F&TV, PD
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8,826
I wear a Fitbit which tracks my sleep. On nights I use dissociatives my REM and deep sleep drop to about half what i get on regular nights. I wake up feeling unrested.
Interesting! I've not got a smart watch but this feature is the main one I'm interested in getting one for (tracking health/sleep).
 

Gregorio888

Bluelighter
Joined
Nov 9, 2018
Messages
55
I have a dumb noob chemistry question that I've searched for and cannot find the answer for. Apologies if it's in this thread, I have read most of it.

What does the "r" in MXPr or 3-meo-2'oxo-pcpr stand for? Does it just stand for propyl (or rather "Pr" stand for propyl,) and they had to add the r because of the MXP "P" = phenidine thing, and the PCP "P" = piperidine? Like would DPT be called DPrT if named like that? Not that anyone would call it that. Or is it some type of isomer thing? I thought those all went at the front of names like d-amp vs l-amp. Or is it something totally different?

I'm guessing the first, but I can't find the answer and it's annoying me more than it should. Thanks for any answers!
 

Chris Timothy

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Joined
Nov 8, 2011
Messages
869
Location
not on a throne
I can't justify using this substance, really, considering price and tolerance. Only exception is for answering specific scientific questions pertaining to its nature, like whether a low amount can stabilize / add quality to a high dose of EPE.

I've called it an upgrade before, but with these costs I might as well create a clean laboratory space where I can do the ketamine needle stabbing thing. MXPr's price is reasonable considering what it can add to a troubled life that has never come across MXE, but for veterans it just can't be recommended from an economical viewpoint.
 
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