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- Nov 3, 2008
- Thousands of Miles Away From You
Micron Filtering Mega Thread and FAQThe micron filter is utilized to ensure sterility and safety of intravenous drug use. For many pharmaceutical tablets which are desirable for injection depending on the individual (Ritalin, OxyContin, Roxicodone, Dilaudid, Morphine Sulfate, Suboxone, Subutex, Dormicum, etc), the use of a micron filter is necessary to remove unwanted inactive ingredients. Some inactive ingredients like talc (for example, which is present in Ritalin and OxyContin, among many other pills) are best kept out of IV solutions, due to the fact that it ends up in your lung eventually.
What is micron filtering?
What is micron filtering?
Over time, if you continue to inject pills, it is better to micron filter, so as to avoid the build up of tablets' inactive ingredients into your body.
Why micron filter?There are several case studies of such individuals, and you can view the Case Studies thread for reasons why you should micron filter. One specific example involves a successful lung transplant due to talcosis of the lung. The patient acquired talcosis of the lung because they injected enough talc within Ritalin tablets.
What will I need?1) Whatman Sterile 0.2 µm PVDF Micron Filter
2) Luer Lock Needle Tip
(Any gauge will do, pictured below are 18G needle tips)
3) Luer Lock Syringe
(Size varies on how much solution you are preparing at once, pictured below are 25CC luer lock syringes)
4) Bacteriostatic Water; 0.9% benzyl alcohol
(Solutions that are going to be used within a day or so don't necessarily need a preservative, but for the most part, any solution that you're planning on using for a week or two should have a preservative such as benzyl alcohol).
WARNING : Do NOT inject bacteriostatic water by itself. Intravenous injection of Bacteriostatic Water for Injection without a solute may result in hemolysis. You can read up on hemolysis here.
5) Rubbing alcohol pads.
(You will need to sterilize the surface of pre-sealed vials)
6) Vial for storing your newly created solution. For this tutorial, we're going to use a pre-sealed vial, such as the one that the bacteriostatic water is being stored in (pictured below; so you can see the rubber stopper). You can also use a media bottle for this purpose (also pictured below), though using a vial is a lot more convenient. If you do not want to use a bacteriostatic water bottle, or cannot (you don't need to use all 30mL to open one up), then you will also need an extra pre-sealed glass vial (clear or amber).
7) Pills/Drugs. Obviously, last but not least, you will need your own pills/drugs to micron filter. Bacteriostatic water is not safe to inject by itself. Feel free to choose any pills/drugs you like to micron filter, however pictured below are what I am choosing to micron filter for this example for you all (three 8mg Suboxone tablets).
How Do I Micron Filter? - The Procedure1) Remove luer lock syringe from packaging. Pull the plunger back. Insert pills. Replace the plunger.
2) Sterilize the stopper of the bacteriostatic water. Attach needle tip to the syringe, insert needle into bacteriostatic water vial. Draw back desired volume of bacteriostatic water. Remove the needle from the vial.
3) Replace the needle tip with a micron filter. Shake the syringe until the pills have dissolved. *
4) Slip on a new luer lock needle tip to the end of the micron filter. Sterilize the stopper of the vial you wish to store your solution in. **
5) Push the needle through the stopper of the vial and push down the plunger, slowly but surely. Be careful not to exert too much pressure.
6) When complete, carefully remove the needle from the vial. Store the needle and syringe safely for exchange, and discard the used micron filter.
* Depending on what pills you are using, you might want to pre-crush/split/filter them before this step. I must note, unless you are micron filtering Subutex or Suboxone, it is strongly recommended you pre-crush your pills. This method with backloading un-crushed pills will take some time for other, much smaller, harder to dissolve in water whole pills. It may take up to 15-20 minutes, or even longer. Some pills are designed this way, so to save you the frustration, just crush them up if you're not absolutely sure shaking them in water will help them dissolve in a few minutes. You can also wait to replace the needle with the micron filter until after the pills have dissolved, but I would be careful shaking about a large gauge needle in the air. Or, you can re-cap the needle with the plastic guard so as to protect the sterility of everything. These are all great ideas.
** If you are using a media bottle, you don't need to waste another needle tip - just secure the micron filter over the mouth of the media bottle.
Now that you've read all of this, it's likely you'll want to repeat what I've done here. So it naturally begs the question,
Where can I acquire all of these supplies?<LINKS REMOVED UNTIL FURTHER NOTICE>
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