I snorted, i.m.'ed, and i.v.'ed methoxetamine. It's just a matter of getting the right dosing.
3-MeO-PCP ~ PCP (~ 1 : 1)
PCM ~ PCP (~0.8-0.9 : 1)
PCE > PCP (~1.5-2 : 1) etc. etc.
15mg of PCE HCl snorted is enough to wipe me away into a "PCE-Hole". For my first methoxetamine dose I used potency relationships like these above + some known SARs. ~100mg of methoxetamine HCl is enough for me intranasally to put me in a "MXE-Hole". I started from 50mg when i.m.'ing (I actually prefer to inject such drugs i.m. than snorting them if I'm alone, e.g. If I was to go out, I would snort ketamine and if I was to stay home, I would inject ketamine).
Metabolism of MXE is like this: 2-carbonyl group is reduced 2-hydroxy, methyl is cleaved ("cloven" if you prefer) at 3', so there's probably 3'-HO-MXE present (3'-HO-PCP is 5-8 as strong as 3'-MeO-PCP), and of course deamination to N-normethoxetamine. 2-(ethylamino)-2-(3-hydroxyphenyl)cyclohexanone would be stronger or I'm missing something with 2-carbonyl arylcyclohexylamines... Why methoxy at 3 and not hydroxy? For weighting purposes?
Methoxetamine is more potent than ketamine on a miligram basis, I figured out (no substituent at ortho position, N-ethyl instead of N-ethyl,
m[/]-methoxy ~ no substituent = no wonder). Anyway, SAR of 2-carbonyl arylcyclohexylamines is quite different than if there was nothing. I can inject intramuscularly 100mg of ketamine to go K-Holing. With MXE I can snort 100mg of it but ~70mg injected i.m. is enough and ~50-60mg i.v.'ed is enough.
Intravenous injection is almost always equal to immediate black-out for dissociatives. With intramuscular injection you've got like 1-2 minutes to pull out the needle from your muscle and put a cover on the needle so you don't hurt yourself while X-holing (although one mostly doesn't move at all).
*2-carbonyl concerns cyclohexane ring
3'-methoxy, 3'-hydroxy etc. concern phenyl ring
I successfully diluted 10 mg in 0,15 ml water (give and take), 0,10 ml was not enough.
The water was room temperature
Why would you need such a concentrated solution? For intraspinal injection?
You may inject 5ml max in your thigh or upper outer part of your buttock. And the amount of solution given intravenously has no limits (well, for like 100ml of some solution with electrolytes you just need to have it injected very slowly).