collection of bad boys of SCIENCE

[allone]

ep1 se1
The curcumin King!

Bharat Aggarwal - Wikipedia

en.wikipedia.org

as we go, ill keep finding new and new SCIENCE bad guys exploiting and destroying people's lives. just because they managed to finish college and get a certain degree in SCIENCE

 

[Jabberwocky]

What’s interesting about that wikipedia article is the way it demonstrates the self-correcting nature of Science.

The articles were retracted. Whether the guy was a fraud or just a poor researcher kind of doesn’t matter. Science, as a field of practice, identified him and resolved the error.

What is a little surprising is that the peer review process didn’t catch him out sooner. But that is a known flaw of peer review in that it rarely has the raw data to re-run the analysis. However I believe some journals are now requiring this.

If you really want to knock over one of the pillars holding up science look into the studies that are not replicable. Also read Bruno Latour.

 

[Jabberwocky]

for balance (off the top of my head), scientists who have massively improved our lives:

Newton and Leibniz (without classical mechanics and calculus science would not have progressed)

Carnot - ok he was studying cannons for war, but the carnot cycle is incredibly important to this day, we wouldn't have fridges without it

Pasteur, Jenner, Salk, Offit - improving our understanding of disease and developed vaccines. there are too many researchers of specific diseases to mention, even within one, like HIV, there are probably hundreds

Turing- father of modern computing- his precursors Lovelace and Babbage, and colleagues such as Kleene and von Neumann. Followed by Berners-Lee for givin us the internet, enabling you to post this

Watson, Crick, Franklin- revolutionised medical science

Aristotle, Anaximander, Pythagoras, Euclid - and other leaders of their time, followed by Khwārizmī and his contemporaries during a golden age that western-centric views describe as the dark ages

LLoyd, Deutsch, Aspuru-Guzik- working to bring about the next scientific revolution that will change medical science overnight

Salzberg, Clavijo, Heng Li - and others working to help biologists make sense of the huge amount of data they create, with applications ranging from supporting crop science in uncertain times to tracking diseases

Cox and Al-khalili - improving public interest in and understanding of science while being leaders of their fields

Landauer and Noether- to me personally their work is some of the most beautiful and inspiring, maybe less of interest to others but their results are widely applied. Noether was a pioneer and remains an inspiration to women in male dominated subjects to this day.

these are just the ones that come quickly to mind with very obvious positive effects. for every bad apple there are hundreds of honest and hardworking people working to improve everyone's lives.

 

[SKL]

Followed by Berners-Lee for givin us the internet, enabling you to post this

I demand Berners-Lee stand to account for tranny-giantess-inflation-vore-My Little Pony porn. (No, but seriously, I dunno if I'd characterize the internet as something to be thankful for in terms of effects on society at large.)

 

[Jabberwocky]

(No, but seriously, I dunno if I'd characterize the internet as something to be thankful for in terms of effects on society at large.)

i take your point, but things like GISAID, NCBI, and ENSEMBL wouldn't be possible otherwise (am sure other subject areas have similar too), nor resources like BLAST and enrichr, nor arXiv and bioRxiv. these are vital resources if we want to continue to progress, treat diseases, etc.

two other examples- the red cross have trained people in places where they are expecting large earthquakes. they have a solution that works on basic mobile phones to direct volunteers to warehouses of medical goods, food, etc when they happen, as the standard routes will likely no longer apply. MomConnect in South Africa helps pregnant women.

 

[Jabberwocky]

for balance (off the top of my head), scientists who have massively improved our lives:

Newton and Leibniz (without classical mechanics and calculus science would not have progressed)

Carnot - ok he was studying cannons for war, but the carnot cycle is incredibly important to this day, we wouldn't have fridges without it

Pasteur, Jenner, Salk, Offit - improving our understanding of disease and developed vaccines. there are too many researchers of specific diseases to mention, even within one, like HIV, there are probably hundreds

Turing- father of modern computing- his precursors Lovelace and Babbage, and colleagues such as Kleene and von Neumann. Followed by Berners-Lee for givin us the internet, enabling you to post this

Watson, Crick, Franklin- revolutionised medical science

Aristotle, Anaximander, Pythagoras, Euclid - and other leaders of their time, followed by Khwārizmī and his contemporaries during a golden age that western-centric views describe as the dark ages

LLoyd, Deutsch, Aspuru-Guzik- working to bring about the next scientific revolution that will change medical science overnight

Salzberg, Clavijo, Heng Li - and others working to help biologists make sense of the huge amount of data they create, with applications ranging from supporting crop science in uncertain times to tracking diseases

Cox and Al-khalili - improving public interest in and understanding of science while being leaders of their fields

Landauer and Noether- to me personally their work is some of the most beautiful and inspiring, maybe less of interest to others but their results are widely applied. Noether was a pioneer and remains an inspiration to women in male dominated subjects to this day.

these are just the ones that come quickly to mind with very obvious positive effects. for every bad apple there are hundreds of honest and hardworking people working to improve everyone's lives.

Wow. You win BL for today. Possibly the whole month.

 

[Jabberwocky]

haha thanks @Atelier3 - a somewhat dubious honour but i'll take it!

 

[atara]

exploiting and destroying people's lives.

as far as i can tell nobody's life was destroyed in this case except the culprit
he mostly took advantage of people who are afraid of mainstream science (for stupid reasons) by offering "natural" solutions to complex problems (see e.g. his book) and as far as i can tell this thread aims to make life easier for people like Dr. Aggarwal

 

[ions]

Dr. Jones formerly a chemistry professor at Binghamton University is the scientist who said do not pass go in terms of honoring my doctorate. There is a special place in hell for this fucking guy.

 

[Skorpio]

RB Woodword - old school organic chemist who realized total synthesis as an art form. He would anthropomorphisize molecules and his papers have a poetic quality to them that is rarely seen in contemporary science. Reading about him makes me wish I became an organic chemist.

Sasha Shulgin - all of you should know why he is here, man is a legend. Beyond knowing and loving the tryptamine and phenethylamine backbones, I have found him one of the few old-school psychadelic characters who was able to approach the topic without infusing mysticism into the phenomenon if tripping.

Alice Ting- She led the development of proximity biotinylation, where an enzyme that generates peroxyl radicals is fused to a protein of choice, and then biotin is added to the cells. This puts a biotin label on everything nearby which allows fit isolation of biotinylated proteins for mass spec analysis. This technology allows for snapshot like comparisons of local protein envinronments in living systems and the performance of really elegant experiments.

 

[4meSM]

Paracelsus - The grandfather of pharmacology, famous for the phrase " the dose makes the poison". He established that chemicals (even minerals and metals) could be used to treat disease, he revolutionized the medical field. He also invented laudanum, an opium tincture.

Isidor Isaac Rabi - Discovered nuclear magnetic resonance (which got him a nobel prize in physics), worked on the manhattan project and made substantial contributions to radar technology. Thanks to him we now have magnetic resonance imaging AKA MRI, one of the most powerful diagnostic tools, can also be used to record cool videos of the brain in real-time, it's also completely benign/non toxic and non invasive.
NMR spectroscopy was also developed thanks to his work. NMR is probably the most powerful analytical technique when it comes to structure elucidation, it can be used for a ton of stuff such as identifying the 3D structure of unknown molecules. AND it doesn't destroy the sample during the process.


Emmanuelle Charpentier and Jennifer Doudna - Both were awarded the nobel prize in 2020 for the development of CRISPR-Cas9. You have probably heard of this one, it's a genome editing tool which will probably change the future of humanity in a major way (actually it already has).

And last but definitely not least:

Nagai Nagayoshi - He discovered ephedrine as the active ingredient in the ephedra plant, he also extracted it and characterized its chemical structure for the first time.
But that's not all... He realized ephedrine was pretty cool but deep down he knew there was more to it. So what did he do? You guessed it, he invented meth.

 

[allone]

What’s interesting about that wikipedia article is the way it demonstrates the self-correcting nature of Science.

The articles were retracted. Whether the guy was a fraud or just a poor researcher kind of doesn’t matter. Science, as a field of practice, identified him and resolved the error.

What is a little surprising is that the peer review process didn’t catch him out sooner. But that is a known flaw of peer review in that it rarely has the raw data to re-run the analysis. However I believe some journals are now requiring this.

If you really want to knock over one of the pillars holding up science look into the studies that are not replicable. Also read Bruno Latour.

what about all the other guys who were never caught and still have science articles people read and believe? what about the future? doesnt look bright to me when it comes to science because its more and more BUSINESS AND POLITICS. only the little scamming science rats get caught!!! its dirty SCIENCE business just like any business big sharks eat the little fish.
but anyway, you might say wellllll eventually it will catch up! whats the point of following something when it keeps changing and when you are gone, you just believed in fairy tales? wow sounds like religion to me a bit here....

 

[allone]

oh and btw for the guys who always use "you wouldnt be here if the internet wasnt created by a smart scientist" i have belief if one didnt do it, another will. internet was going to be invented at one point in time, regardless. in another universe or dimension, maybe some child created it? and why do i so strongly believe in such a thing? because the EARTH is a living internet connection. i first read about mycelium being the nature's internet and then proceeded to find out even more things connect all together on this earth. AS IF GOD created the internet if you will! and if GOD created the internet, and then some SCIENCE EGO MANIAC comes along and takes all the credit, then SCIENTISTS act like GODs, but do not believe in them. that is so ironical! the SCIENCE GODS disapproving of GODS. haha

 

[Gaffy]

Niiice

 

[Xorkoth]

I love how this thread, other than allone's ranting and finding a couple of specific cherry picked examples (like, yeah of course some scientists have been bad people, some people are bad people, what's your point?), is full of examples of scientists who have improved all of our lives with their work.

 

[allone]

I love how this thread, other than allone's ranting and finding a couple of specific cherry picked examples (like, yeah of course some scientists have been bad people, some people are bad people, what's your point?), is full of examples of scientists who have improved all of our lives with their work.

yeah but being in control or having a very powerful occupation (involved in politics, corporations or being a scientist) can make one bad person extremely bad for all of mankind!! thats the point im making. and yeah, lots of contributing scientists sure. when you say good examples of good scientists do you also mean the one mentioned who created amphetamines, and also shulgin, who created DRUGS???
ill never figure out the cult status of shulgin. the guy was MAKING DRUGS jeez christ! its not like he cured cancer, you know?

 

[thegreenhand]

yeah but being in control or having a very powerful occupation (involved in politics, corporations or being a scientist) can make one bad person extremely bad for all of mankind!! thats the point im making. and yeah, lots of contributing scientists sure. when you say good examples of good scientists do you also mean the one mentioned who created amphetamines, and also shulgin, who created DRUGS???
ill never figure out the cult status of shulgin. the guy was MAKING DRUGS jeez christ! its not like he cured cancer, you know?

his drugs have certainly cured my depression before

amphetamines are used to help millions of people manage their adhd, most people have little to no side effects

 

[Skorpio]

who created DRUGS???

This is bluelight, a drug (harm reduction) forum. I'd bet that quite a few of us are fond of drugs. If this were a forum centered around a different topic such as gardening, I would wager that a different crop of scientists would be represented.

Personally for me Shulgin was my first introduction to medicinal chemistry and the practice of performing rigorous structure activity relationships. Reading his books when young definately kindled my interest about chemistry and pharmacology, helping inform the education and research I chose to pursue.

Although I am not sure if you would see that influence as a positive thing, given your dim view of science.

 

[Jabberwocky]

The other reason @allone should admire Shulgin (I think) is that he worked outside the scientific-industrial-pharmacological complex. For the larger part of his career he was not part of this system that @allone despises.

 

[allone]

his drugs have certainly cured my depression before

amphetamines are used to help millions of people manage their adhd, most people have little to no side effects

which ones cured your depression? he didnt create ayhuasca, lsd, peyote or shrooms. top of the chain psychedelics!

regarding adhd, its controversial because US is still the only country in the world i know of that allows and even argues for it, as it is some type of a brain disorder, even a disease and needs treatment. FACT IS! its caused by many things and figuring it out which things specifically cause it for each individual and you can help yourself a lot in this department beyond relying on shitty amphetamines. I cannot think of a single person being on amphetamines more than 5 years and functioning normal at such point. Personally I have had adhd issues but i fugured its certain toxins and things i have been consuming so i changed my lifestyle and it worked. its especially harmful to kids! it completely fucks you up SO why give amphetamines to kids though?? there are a lot of studies, good diet and especially fish oil helps just as much. there is a library of 100 herbs that can also help!!
I would recommend a lot of things, especially good lifestyle exercise and diet, but when it comes down to medicine, just take tianeptine. I dont recommend it to kids though. I do not recommend A SINGLE DRUG TO KIDS, EVER! Even if kids have the flu, the cold, any allergy symptoms or issues, i would still not give them DRUGS!
Maybe because I grew up in the ancient world, being from the ancient Thracians on the Balkans, I am used to witnessing ALL kids growing up especially strong without any artificial science based treatment or help in any way. It was me among the few who decided to leave the old world and go into large metropolitan societies that have caused me to become so sick and pale in comparison. Sometimes when i visit the old lands, they view me as a zombie. I just tell em I am EDUCATED and I use SCIENCE now and i supposedly have a better life. But then even the smallest person if so wishes to do that, can throw me around few times and say "HAH! Sure thing "konsomolec" which means "consumer" or someone relying too much on society and science to exist, in loose definition.
BUT not to drag this any further, I do believe US and other "western" advanced countries are huge BS creating and making up tons of diseases and allergies and crap only because of their crappy corrupt societies and SCIENCE business. The further I go and lose myself into huge metropolitan cities, the more I understand this, I am becoming a zombie. It is especially funny and true so many of us are so fascinated to the whole zombie phenomenon. So sad we do not realize the whole concept IS MOCKING US! Its like looking at a mirror and being so fascinated thinking, "as long as its not me, its entertaining" while its actually you looking at yourself haha so sad!
But anyway, Im a zombie now. I cannot laugh at all the other zombies or use them as entertainment. Those days are long gone. I rather think of how to finally liberate myself before its too late as time is ticking....