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Mdma And Anti-depressants - Mega Merged

BilZ0r

Bluelight Crew
Joined
Dec 15, 2003
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I know there's allready a FAQ on this subject, but it doesn't answer the questions I see day after day.

I'm on an antidrepressant, can I roll? Chances are, no. If you're on an SSRI (e.g. Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac), Fluvoxamine (Luvox), Paroxetine (Paxil) and Sertraline (Zoloft)) if you take MDMA, you will not feel much of anything. If your on a Dual Uptake inhibitor (Duloxetine (Cymbalta)) You won't be able to roll. If you're on a SNRI (Venlafaxine (Effexor)) you might be able roll, it seems to vary from person to person. If you are on an SDRI like Bupropion (Wellbutrin) your roll should not be effected much at all. It is not especially dangerous to take MDMA and these antidepressants and MDMA at the same time (i.e. you wont get serotonin syndrome), but don't be disapointed if nothing happens.

If you are on an MAOI (phenelzine (Nardil); tranylcypromine (Parnate)) do not take MDMA, this is a life-threatening combination.

Mirtazapine (Remeron) will effect your roll, it will alter the way it feels, but it may or may not lessen the strength of the roll.

Unlike the antidepressant effects, the MDMA-blocking effects of SSRIs only take one or two pills to start.

Okay, I can't roll because I'm on an antidepressant, can I just stop taking the drugs for next weekend, so I can roll? Again, chances are, no. Most antidepressants hang around in your body for several days, and take days and days to clear from your system. Also, long term use of antidepressants decrease the amount of serotonin transporter (SERT) in your brain. The SERT is how MDMA releases serotonin; less SERT, less serotonin will be release.

Okay, so I need to quit my antidepressant to roll, how long after I quit can I roll If you're taking antidepressants, you're on them for a reason. You need to think, is rolling worth my symptomes coming back? Also, quiting antidepressants can cause serious withdrawal symptomes. If you're going to discontinue your antidepressant, you need to talk to your doctor about doing so. But after you've quit, and your withdrawal symptomes are over, how long before you can roll? I am not awear of any scientific liturature looking at the return of SERT after the cessation of chronic antidepressant use, however anecdotal information supplies that you should wait somewhere between a week and a month for the rolls to return to full strength.
 
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I have quit antidepressants (prozac) for 3 years and I am still unable to roll. What do you think has happened to my brain? SSRIs really screwed me up bigtime and I'm looking for a cure. Is there any way I can induce my brain back to normalcy?
 
randomSoma said:
I have quit antidepressants (prozac) for 3 years and I am still unable to roll. What do you think has happened to my brain? SSRIs really screwed me up bigtime and I'm looking for a cure. Is there any way I can induce my brain back to normalcy?

Maybe they aren't good rolls? The prozac should be out of your system entirely by now. Search the forum for other reasons why people aren't able to roll.
 
I've been on mirtazapine now for about 6 months. I can still roll if the pills are good. But I've been rolling now for many years, and I've long since lost that amazing magic you feel the first few times. I still love rolling and it still feels great. I it's think the poor quality of the pills that have been around for the last few years that has been most dissappointing to me. Most pills I have seen recently are a meth/MDA combo. It's rare to find pure MDMA pills that have more than 50-60MG. The JK's a few months back were MDMA, but you needed to do 6 to get a really good roll.
 
Lies, I've been on prozac for about a year and I had the best MDMA from Vancouver last night. Me and my friends spent the night completely twacked, we all ended up naked. I think that maybe antidepressants can eliminate the functioning of some cells and fluids and watnot for SOME people. I still roll as good as always. Of course, it's possible that some X doesn't work with happy and some do. Either way, it's not a risk that's dangerous, it's just a chance that you won't get that high. I recommend that people on prozac be careful to get good quality pills to get their money's woth.
 
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i myself was on prozac for 1 year , and still find my rolls to be somewhat quite different from what they used to be + the negative side effects are more pronounced. The feeling of magic on MDA is gone & MDMA just makes me feel alert aside from loved up. any sugguestions? Prozac dose was 20mg/day
 
^ Yeah, that sounds like what a lot of people get. It shouldn't stop all off the effects, just most of the good ones. It won't be rolling really.
 
^ I'd be more worried about you taking psychiatric advise from you're mom.
 
I have a question


I recently started taking effexor. You stated above that I "might" be able to roll. I've definately noticed that the high sucks in comparison to before taking the medication, and I don't really get the good feelings off pills.

By "might", would this mean that there's a chance I could get high if I'm lucky in the future or are the current results of pills as good as its gonna get?
 
^ Might as in, some people report being able to roll, and some people don't. It would seem you are in the latter group
 
Well this weekend was interesting

I found a guy with pure MDMA powder. I was sceptical about buying because I though that the only thing that got me high was whatever was in pills besides the MDMA.

But I did end up feeling pretty damn good off them. Not "fucked", like the people I was with seemed to get, but I did get a good buzz off them. It was also great to be able to just go to bed after with no sketch or tossing and turning trying to sleep.
 
Just wondering if anyone knows anybody that has taken ecstacy, and has been on paxil for some time and has been able to roll? I have read up on antidepressants and x so I know that technically speaking they shouldnt be able to.
 
well i have tried to roll while being on Effexor, the pill was a proven 100% high quality product,

what i noticed, slight high, very very slight roll effects, and large dialated pupils

apart from that nothing.
 
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Buproprion should effect the feeling show what, but probably not much at all. But I'll add that in, thanks for the request.
 
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