Opioids Buccal mylan fentanyl patch duration?

I hope that i am posting this in the proper place, seriously couldnt find a proper answer anywhere, anyways. A friend of mine has a question about this shit, I know all about the potency of fentanyl, as does he. oral morphine it takes about 100-150mg and for intranasal oxycodone roughly 40-60mg oral probably a bit less, or something along those lines. Hydro CWE atleast 80mg and typically just for a medium hit. But thats not the point.. Just reassuring everyone that an overdose would only happen if intentional

50mcg mylan's, cut into typically only 1/10th to maybe a sixth at most put onto tounge/gums/cheek, whatever. The question is roughly how long is that little piece of plastic really good for? Am aware that it is 72hrs right there plastered on, the plastic outside, which by the way is easier to open that some tv dinners... But since its a different route of administration/not what was intended by manufactures I would only assume that the duration would not be the full 72hrs... Am also aware that if put onto the skin and heat is applied it increases how quickly its released. One would think that its warmer in the mouth than on the skin, room temp? Under clothing would increase obviously.. Chewing on the plastic would increase how quickly it is as well one would assume??

Can anyone shed some light on these crazy things and how long it is worth buccal? smoking that shit is out of the question, if it can even be done since its not the gel filled fiascos.

1-6hours depending on if you are chewing it or just letting it sit. i have never just let one sit there without chewing on it

4-8hrs. It was my primary DOC and ROA was buccal, I used in this way for about 6 months with about 3 months before transdermally (chronically for pain and even at 25 uG/hr and an already high tolerance I was permanently nodding for at least 2 months). His tolerance is too low to take these safely, even 1/10th might make him a bit sick but there are additional dangers. Don't let him chew it if it makes it more intense until you see how he responds (chewing didn't work for me - I had Janssen-Cilag Durogesic patches and they didn't seem to work better while chewed). To give you an idea of my tolerance at the time of my first attempt at buccal administration, it was such that orally 400mg morphine didn't even effect me (I felt nothing) but the first time I popped a 25uG/hr patch in my mouth I started passing out at my computer after 20m. I almost did so with the patch in my mouth. Make sure you or someone monitors him the first few times until he finds a comfort zone, he might want to redose too soon. I also found that redosing after coming down tended to make you very sick the next day, an opiate hangover, although you might not OD or pass out and be able to keep yourself at the same level by using more than one dose (make sure he removes the previous one to prevent an OD).

There is also the theory that potentially the fent in the matrix is not evenly distributed which is a major hazard because a 50uG patch containing all the fent in 1/10th area is almost certain death for someone with a tolerance as low as his. I never really experienced an unevenly distributed patch, but I used full or half patches most of the time and my tolerance was such that I would have survived the full patch (at whatever dose I was at at the time - max was 75uG patches with around 10mg of fent in each one - they contain much more than what you'd expect at 100% efficiency, in fact I think it was around 14mg). I did split some into about 1/6ths, at times to maintain, and found that they were roughly 1/6th the strength I expected. My doctor said that the uneven distribution was a valid enough concern for her to refuse to prescribe me a slightly higher strength (75-100) and let me cut them in 1/2 and have them last for twice as long. I had a valid problem with the transdermal duration and was effectively asking for a dosage drop (from 75uG - 50uG/hr) so I doubt her refusal was concern over abuse.

So basically if he cannot even wear the patch without overdosing, I have serious concerns over whether he will be OK or not. Even 1/10th of a 50uG absorbed in 1hr (if chewing does indeed release all in 1hr) and assuming 25% efficiency and even distribution you still end up with 50 x 72 x 0.25 = 900uG fent / hr / patch. 900ug/10 (split it into 10ths) = 90uG / hr. That's WAAAAY too much for someone who can get off on "only" 150mg oral morphine, it's possible he won't die but if he doesn't he will probably get sick. For casual opiate users, messing with this stuff is like taking a 13yr old who gets drunk on 1 beer and giving him a keg of Everclear 190 proof that tastes like orange juice. Has he ever tried to wear the patch? I suggest you halve it and get him to wear it first. Supervise him the entire time it is on and only leave once he takes it off. If he is still conscious 8hrs later, then consider allowing buccal admin of 1/10th.

I wouldn't waste the time using a piece of a mylan buccally or sublinguily for that matter. Just take a piece and chew on it for 15-20 minutes, see how that gets you. Note: chewing the patches after a while will wreak some serious havok on your liver! but im sure you've heard all that before.

I would go ahead and go for it though, as you/your friend probably won't be chewing on them for longer than a week or so, you'll be in the clear.

How exactly does it wreak havoc on your liver? I didn't know that. Was going through 2x75uG patches on really bad days (and feeling like crap the next day - maybe it's effect on the liver was why?). But I never chewed them, only buccal at worst.

That is another question that I forgot to ask about, is there anyway of atleast removing some of the adhesive before putting them in the mouth? Such as putting it on the skin, only to rip it off a second later. The reason that I havent tried that is because I know taking the patch off, then reapplying doesnt work too well because the patch becomes clogged with dead pores.
I also forgot to mention that we have done about twenty to twenty-five patches since they first came around our area, roughly 16 months ago. The beginning was just transdermal, leaving it on for only 12 hours at a time.
I find it interesting how hexxx is concerned about a possible opiate overdose. He has had one close call, left the patch on for too long and smoked too much weed and the combo was just really overwhelming. Nothing like the OD's of intranasal H. Neither of us have ever iV'd (i have had iv morphine, due to surgery, 35mg over about an hr. and then a 4mg dilaudid IM shot a few days after the surgery because the pain was uncontrolled)
150mg of morphine would get him high, not supremely high as in his words "when i hit it" as in, getting as high as you really were searching for in the beginning.
I can only imagine that the adhesives within this stuff has gotta be unhealthy, other than "liver damage" could anyone be a bit more specific of what? Any possible way to avoid this? Not likely but I figured it was worth asking

WTF, are you 12 years old or something? As long as you have some experience which is why I was initially so concerned. Who said I was smoking weed with it?!? Dude, I was prescribed opiates for injuries that were so bad the doctors were certain that I'd die just from the shock from the trauma alone so I used these things for 9 months at high doses everyday! Before that I was RX'd many, many other strong opiates which I used EVERY SINGLE DAY for at least 8 months - ironic you mention insufflated heroin - it had no effect on me the first time I tried it except itching, and that was about 150mg of notoriously potent white powder heroin - and before I even started wearing patches. But you obviously have some street cred since you fell asleep after snorting a soupy solution of low grade tar so you already know all this . Not dick sizing, I'm trying to give you some perspective as to strength.

I know how strong they are and the difference between transdermal and buccal. I had much more than 1 close call and the first time I tried buccal admin with a 25uG after using fent everyday for 3 months (chronic use = over 30 patches in that time) was not one. It wasn't overwhelming since I managed to realize how strong these things actually are and how quick it goes through your cheeks. Something which you apparently have no idea about since your the one asking questions.

But nevermind me, what do I know? I have obviously no experience... Go ahead and be the unlucky one who absorbs an unevenly distributed full patch in the 1/10th piece you cut in under an hour. Your messing with probably the most dangerous opioid that has ever been RX'd ( to humans at least ). Please, I'm not trying to be a dick or question your intelligence or anything, Fent is a killer even when used correctly under medical supervision. When you start speeding up absorption rates and breaking the time release mechanism it becomes exponentially more dangerous. Just have supervision until you / your friend get a feeling for the potency.

Yeah im 12 and I somehow have acquired something that is given to chronic pain patients/cancer patients/car accidents things like that...... I didnt feel like I needed to go into full detail about how long Ive used opiates/now had to because as I clearly stated in the beginning i fully understand how strong fent is. If you disagree thats fine it doesnt matter. There has never been and undistributed patch that I/nor anyone has ever heard of so that I was unaware of. My PM doc and I have discussed going on the 12.5mcg but decided not to. I am too a cp sufferer, 120 10mg norco's with 30 5mg roxi per month for bt pain so its not as if I just take these things casually. Used to do the whole grapefruit/cimetidine shit, dont treat me like I have no idea wtf Im talking about. All I wanted to know was how long roughly it lasted since it was not the manufactures idea for that administration unless it was lollipop version...
And I never said you smoked weed...my friend did it thats what made the combination overwhelming and potentiated the fent to the point of feeling sick.

Sorta got an answer, and a lot of un-necessary belittling. thanks.

OK now I see what you mean. Sorry never meant to belittle you, misunderstood you were talking about your friend and thought you were being sarcastic or something about me taking the patch out before passing out. Don't think I need to reiterate my concerns. Sure you get the point. The uneven distribution is not something common but it does happen.

Good luck and sorry again.

Question about Buccal mylan fentanyl patch

I'm not feeling well so I'll keep this short. First let me say this is a great site! and much needed in keeping people safe. I suffer from a number of issues, cluster migraines, chronic lower back pain, and now what seems to be arthritis in my knees and feet. I also have a few other problems sleep apnea, and colitis.

My question about the patch is using it or cheeking it is the term I have seen used. I have a monster tolerance, until the end of Aug of 2010 I as taking 10 MSIR 30MG, 12 30 mg oxycodone, 40 mg of methadone and oxyfast (generic) I got 2-3 bottles of that a month.

I lost my doctor and had hell finding one who would touch me seeing the doses I was on. I'm now taking 6 oxys 30 a day and 60 mg of methadone, but many days the pain is so bad I take 15 or more of the oxys at one time, 20 of them is not unheard of. I wish I could come off of everything and get my doses down but the pain is to bad.

I got my doc to let me try the patch and he gave me the 100 mcg, in place of the methadone, the patch did nothing for me at all, I tried 3 patches that I could have changed every 2 days but left them on for 3, until the last one and I took it off after a day and a half.

I still took my oxycodone while wearing the patch, and I would take 10 or so maybe 15, but I took my time doing this, a couple at a time to see how it helped the pain, the oxy works great on my migraines, and knees but falls short on my back, it helps some but some days I still can't walk very far at all, half a block maybe.

I tried cheeking the one patch I had used for a day and a half, first a 1/4 and then another..nothing, then I did the have nothing. I still have 2 left and was wondering if I should try one new, and how much, I always play it on the safe side, so maybe just 1/4? or with a tolerance like mine a half? or maybe just not F with it at all and hope this new doc I see this week will write for OC's or that kinda new one Opnea something like that, and I know they messed with the OC's and they are now OP's..I just want to stop the pain, and if I feel good also that's a plus!! Thanks so much for any info on this.
P.S forgot to say I'm back on the methadone, about 100 mgs today.