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@iom - it seems that mean receptor occupancy time is critical. My own pet hypothesis is that it's the binding-unbinding cycle that is a... -
I'm generally a big proponent of the hypothesis that pharmacokinetics can have a significant impact on the qualitative effects of a...
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M!$TER-ED reacted to JackARoe's post in the thread Tryptamines My stuck, suicidal ass realized he should probably take LSD with
Like.
Mac, for all his serious troubles is a Rock. Honestly I did not even read the title of the thread, just glad that Mac is here still... -
WWellTram replied to the thread Harm Reduction Bupropion - started abusing it. Need something safer..Yes. Fast acting SNRi, sigma receptor agonist and NMDA antagonist + it's metabolite is powerful NMDA antagonist. By combination of DXM +...
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JitteryKitteryDoo replied to the thread Misc r/huffingcommunity2 is the absolute gutter of the drug community.I wonder what the crossover of users is with r/dph, some of those people are so far gone -
Acid base extraction, if it's just salt it's cut with. K HCl --- xOH ---> K freebase Extract with toluene/CCl3/hexane, seperatory...
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placebonaut replied to the thread Alcohol Any substance besides cannabis that can ease the obsession to drink at night?.I'm in the same boat as you, would love some other ideas as well! I tried swapping 1 evil for another:- Kratom, GHB/GBL, cannabis... -
neversickanymore replied to the thread Social The NEW "What Song Fits Your Current Mood" Thread.Feed The Dog tonight.. 😁 -
placebonaut reacted to streaM Freak's post in the thread started drinking again after a year and 3 months, now im probably getting sent to rehab with Like.
I'm not very good at emotional support, so i won't pretend to be. You're so young... this isn't your fault; it is how society is set up...
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placebonaut reacted to emkee_reinvented's post in the thread started drinking again after a year and 3 months, now im probably getting sent to rehab with Like.
Kicked out of school 3 times for showing up drunk, wow. Though could have been worse. You are not a teacher. Yet. Lot of teachers with...