I've never prepared for withdrawals because I never planned on stopping but whenever I had to stop because I was forced to, or found myself unable to get dope for some reason this is what I've found the most helpful:
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kratom- (this is definitely the most helpful detox tool I've ever used)
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Loperamide-attaches to opiate receptors in your gut, with enough it seems that some can cross your blood brain barrier and work kind of like buprenorphine or methadone, though this isn't recommended as this can be quite dangerous.
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Clonodine -(this drug is actually quite amazing, a lot of people don't like it cause it isn't an opiate, but it's the only thing that will allow me to sleep without benzo's or substitute/detox opioids)
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Gabapentin/Neurontin- this drug is nice in then it kind of puts me in a fog where I don't feel the withdrawals, I don't feel very good on it either but it helps me ignore symptoms. Lyrica works the same if not better.
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Zofran-As you said
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Benzo's-Specifically, alprazolam or clonazepam, something strong to knock me the fuck out. Wish that Triazolam was easier to obtain cause then I'd just be blacked out and passed out throughout the whole withdrawal period.
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Amphetamines-I've noticed that these work for some people and for others it makes them sicker. I've found that I could cut down my opiate use massively by replacing it with a methamphetamine addiction which is in my opinion worse (for me- I tend to get out of control), but meth and adderall for some reason make me feel way better (where as crack will make me want to blow my brains out as I blow shit out my ass)
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Promethazine/phenigren- If you can't get zofran, though I imagine that being an antihistamine it might make RLS worse
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Zanaflex/Tinazedine- Muscle relaxant similar to Clonodine but shorter acting
also might want to check
this thread out