Visionary_Kpsycho
Bluelighter
I know that THC affects certain receptors in the brain. But what does it really do? Does it release endorphins from the brain?
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CD Moderators: someguyontheinternet
Why do we feel high from smoking weed?
- Thread starter Visionary_Kpsycho
- Start date
It's a baby!
Bluelighter
- Joined
- Dec 23, 2007
- Messages
- 652
No endorphins, though it probably does release dopamine in your mesolimbic system or something like that, which is why it feels rewarding and can be habit-forming for some, and will also add to the high obviously.
I'm pretty sure wikipedia has a decent article on marijuana's neuropharmacology actually, you should check it out.
But yeah AFAIK it doesn't have anything to do with endorphins, though I can see why you'd think that, people have always told me that the closest feeling drug to opiates is pot.
Edit: according to wiki:
"In addition, it has been shown that cannabinoids, through an unknown mechanism, activate endogenous opioid pathways involving the μ1 opioid receptor, precipitating a dopamine release in the nucleus accumbens. The effects of the drug can be suppressed by the CB1 cannabinoid receptor antagonist rimonabant (SR141716A) as well as opioid receptor antagonists (opioid blockers) naloxone and naloxonazine.[12]"
So I guess it does do something to opioid receptors, but I don't think this is the same thing as endorphins.
Meh I really don' tknow what the hck I'm talking about here, someone more knowledgable will come along.
I'm pretty sure wikipedia has a decent article on marijuana's neuropharmacology actually, you should check it out.
But yeah AFAIK it doesn't have anything to do with endorphins, though I can see why you'd think that, people have always told me that the closest feeling drug to opiates is pot.
Edit: according to wiki:
"In addition, it has been shown that cannabinoids, through an unknown mechanism, activate endogenous opioid pathways involving the μ1 opioid receptor, precipitating a dopamine release in the nucleus accumbens. The effects of the drug can be suppressed by the CB1 cannabinoid receptor antagonist rimonabant (SR141716A) as well as opioid receptor antagonists (opioid blockers) naloxone and naloxonazine.[12]"
So I guess it does do something to opioid receptors, but I don't think this is the same thing as endorphins.
Meh I really don' tknow what the hck I'm talking about here, someone more knowledgable will come along.
Firstly, Opiates feel alot different to pot in the fact that with pot everything is more funny and it's just a different feeling, opiates make you want to lie down in a warm blanket in front of a TV.
What wikipedia says is accurate though but in laymans terms it basically means that the cannaboids in cannabis activate certain pathways in the brain which release dopamine (dopamine is the stuff that makes you feel good).
There are of course lots of other factors and things which make you feel like you do on weed but you would need to understand alot more about the brain to understand how it all works.
What wikipedia says is accurate though but in laymans terms it basically means that the cannaboids in cannabis activate certain pathways in the brain which release dopamine (dopamine is the stuff that makes you feel good).
There are of course lots of other factors and things which make you feel like you do on weed but you would need to understand alot more about the brain to understand how it all works.