Well, considering that the many of the drugs used to tread opiod/opiate addiction are also opiods as mentioned in another post' replacement therapy, I don't see much hope.
There would be a lot of money in making such drugs, and there is no way that the large pharmaceutical companies could resist making a shit load of money if that were possible. I cannot imagine that there haven't been hugh attempts. The treatment drugs would be big money makers and help improve the image of Big Pharma. Considering all the money spent on testing drugs on animals, and yet nothing solid. The 1 in 9 success rate of one drug combo, that was probably tested on people who wanted off to begin with is a bit discouraging. The drugs used to treat alcoholism only work on those who are trying to and want to be sober and even with a drug to treat cocaine/ crack addiction, you would probably have to have a substance that treats the psychological aspects of that addiction. So many people use drugs for opiod addiction, to not get sick. Yes I am aware that meth has physical withdraws, but it seems that crack in particular is a psychological addiction. So many opiate addicts( please no opoid versus opiate bs) are just trying to not get sick. Cocaine users and crack users really just want more. There would have to be something developed that really deals with the psychological effects. I just wonder if that would even be possible without major side effects to the brain. I admit I never studied neuroscience but, how do shut down those desires without a replacement therapy or something that wouldn't cause even more brain damage? Other than the limited uses in certain delicate, and limited surgeries, big pharmaceutical companies are not making any money from cocaine, yes I know benzo abuse is common among cocaine/ crack addicts, but the money to be made off a drug that curtains cravings would be hugh. They are trying, there is a real purpose on getting rats, chimps and probably other animals addicted to cocaine. It is more than, huh huh, let's gets these rats high. If the Bupropion and naltrexone was really effective it would be used a lot. I believe that unless there is some hugh breakthrough, Jasperkent is right.