sorry, your right the steriochemistry is wrong on the tcb like compounds, however on the first two they are meant to be the way they are.
let me explain.
the first one:
with dragonfly compounds the more active isomer is the 'r' isomer. this locks the "2,5" into the 2,5 instead of giving it the possibility a reverse looking orientation with there appearing to be oxygens at 3 and 6 opposed to 2 and 5. it seems a common theme with entactogens that there is an oxygen at the 3 position. also doses of most entactiogens and mescaline are over 100mgs. take 100 mgs of a dox and your toast.
if you look at the effects of some fly compounds we see entactogen proporties.
with the s isomer here it puts the oxygen at the 3 position, while keeping the ring. i take out the new "6" position methoxy and leave the "5" methyl to emulate any strange effect that it has as seen with 5-methyl mda (which is an extremely interesting compound when compared to mmda). hopefully we can explore any trends here. how is it that the small methyl group there gives potency and strong psychedelic action while keeping entactogen effects?
as for the chlorine, well lets stick with the "4 position is where the action is"... chlorine seems a more benign halogen as far as sketchy shivers go (this is speculation). of course the full range of halogens and other substituants should be tried here.
so i am going off of the possibility that the 3-methoxy, 4-halo, 5-methyl configuration could be both a great entactogen and strong psychedelic with a higher potency than 3,4-methylenedioxy amphetamines. i keep the furan ring to give a little bulk (its always nice doing the stoichiometry with yeild in mind when your molecule is of higher weight) and to restrict the carbon on the would be 3 methoxy group to see if it needs to be free or not for better result.
also i would like to say i have a feeling all s isomers of the dragonflies, while being less potent, will also have more euphoria and be far less toxic
for 2:
this is the other isomer, the one that should be stronger. here we see there is an oxygen at the 2 (as in the 2c's) and the 3 (in entactogens). im sure this will kick potency in the balls.
perhapse some of the trouble conceptualizing is in the way molinspire configures the molecule?
3:
guarenteed to be a winner.
look at the diference between 2cg and ganesha, the little atom does alot for it. im sure the nbome should do even more.
and from the trip reports on g3 from pihkal... the nuttiness and other worldliness of g3 makes me want to see what effect that ring will have in an nbome.
i read a trip report of tcb-2 describing "jewling"
both tcb and nbome are of high potency, which i assume to be synergistic here. balanced with the g3... should be interesting for sure.
i could be completely wrong. (as with any of these). but like the topic says, which would you like to try? well, this one.
4:
this was suposed to be the tcb version of 5-me-mda, but the drawing tool wouldnt let me add that extra oxygen for whatever reason. the current molecule looked interesting enough. even if it didnt act through the same mechanisms as the 5-me-mda, the tcb aspect should turn those substituants into something interesting.
i believe we would have something completely unpredictable here. and this is the one i would be most interested in trying.
..hmm but after looking back at the others... i cannot say that is true. it is interesting for its own reasons, as the others are.
like i said... if your a cook, PLEASE cook these


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