Lately there have been quite a few threads and posts on here about blacking out on psychedelics.
I can't help but wonder what the hell is causing this... I've been in some unholy states but if anything I find these drugs enhance my memory.
I am no stranger to the amnetic effects of cannabis, valium, booze, dissociatives or codeine. Sometimes when I wake up in the morning I have a hard time remembering what I did the night before.
One interesting thing I notice with psychedelics is that no matter how fucked up I get on them, they leave my memory intact. Sometimes I get confused or forgetful DURING the trip (even to the point where I forget who and where I am) but once I've sobered up I can always remember everything clearly. There have been times where I was sat there tripping balls thinking to myself "I'm not going to remember any of this tomorrow", only to wake up with crystal clear recollection of what happened.
Through what mechanism can the classic psychedelics cause anterograde amnesia? There doesn't seem to be a feasible scientific explanation for this... 5-HT receptor agonists are not associated with impaired memory (unlike GABA-agonists and NMDA-antagonists).
The only explanation I can think of for someone blacking out on the likes of LSD, psilocybin, DPT etc. is if they were also indulging in one of the other substances I mentioned.
I can't help but wonder what the hell is causing this... I've been in some unholy states but if anything I find these drugs enhance my memory.
I am no stranger to the amnetic effects of cannabis, valium, booze, dissociatives or codeine. Sometimes when I wake up in the morning I have a hard time remembering what I did the night before.
One interesting thing I notice with psychedelics is that no matter how fucked up I get on them, they leave my memory intact. Sometimes I get confused or forgetful DURING the trip (even to the point where I forget who and where I am) but once I've sobered up I can always remember everything clearly. There have been times where I was sat there tripping balls thinking to myself "I'm not going to remember any of this tomorrow", only to wake up with crystal clear recollection of what happened.
Through what mechanism can the classic psychedelics cause anterograde amnesia? There doesn't seem to be a feasible scientific explanation for this... 5-HT receptor agonists are not associated with impaired memory (unlike GABA-agonists and NMDA-antagonists).
The only explanation I can think of for someone blacking out on the likes of LSD, psilocybin, DPT etc. is if they were also indulging in one of the other substances I mentioned.
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