opiates are great for depression, esp. oxycodone. not even at doses required for people in pain but low dose(7.5-10mg) oxycodone is very effective at providing a lifted mood(not quite euphoria), stress and anxiety relief, and causing a general increase in motivational thinking/mood.
but addiction from either abuse or physical dependence(with regular use) heavily limits it for other uses. however just like with theraputic long term use with benzos for anxiety(not high dose abuse) or even SSRIs(they have a "discontinuation syndrome" which is a bullshit fancy cover title for withdrawl) if the patient sticks to the lowest effective dose and follows the doctor's orders then a taper is all thats required and its easier than benzos which are more dangerous with dependence and are used long term all the time.
however amphetamines are given for resistant depression and often work wonders, and even though they're addictive they won't cause physical dependence. but still opioids need to be looked into for the treatment of depression.
Wow... I highly encourage you to learn some facts & educate yourself about what you're talking about BEFORE you go talking about it...
First -- "opiates are great for depression, esp. oxycodone. " ... Why is Oxycodone any better for Depression than all the other painkillers out there? Maybe it's better for YOUR depression than other pain killers, but to say that it's the most helpful painkiller for everybody out there suffering from depression is sheer ignorance. Haven't you ever heard that everybody reacts differently to every substance?
Second -- "oxycodone. not even at doses required for people in pain but low dose(7.5-10mg)" ... What the hell are you talking about? Those are the HIGHER dosages of Oxycodone given to people in pain (not including Oxycontin, which is pretty much only ever prescribed to people with terminal cancer or people in IMMENSE, IMMENSE agony, usually those with chronic back pain... Plus it's extended release). People in moderate to severe pain generally get prescribed 5mg pills, & the instructions on the pill bottle generally says either "Take 1 tablet every 4-6 hours as needed for pain" or "Take 1-2 tablets every 4-6 hours as needed for pain". 7.5mg - 10mg isn't a low dose at ALL for somebody recovering from a severe surgery.
Third -- "however just like with theraputic long term use with benzos for anxiety(not high dose abuse)" ... Most people who end up taking higher dosages of Benzos than they're prescribed do so as a way of "self-medicating" their anxiety. Usually when people "abuse" Benzos in high dosages they're doing so because they were originally prescribed it for anxiety, ended up developing a tolerance, then ended up developing so much of a tolerance that their doctors won't increase their dosage any further, & then the Benzo script they're stuck with ends up not being able to control their anxiety anymore, & they clearly can't function normally or live comfortably at all when their anxiety is insufficiently treated (hence why they were put on Benzos in the first place), so they increase the amount that they take on their own for the purpose of achieving effect therapeutic results. You can't try & seperate people who take Benzos into two "groups" like that.
Fourth -- "or even SSRIs(they have a "discontinuation syndrome" which is a bullshit fancy cover title for
withdrawl) " ... This flat out pissed me off, honestly. I mean, how the HELL can you say "just like with Benzos & SSRIs..." ... That's some ignorant shit. Benzos are notoriously addictive, & Benzo withdrawal is perhaps THE worst withdrawal out there, etc etc ... It doesn't have much of a damn thing in common with SSRIs. SSRIs are not addictive... They're actually incredibly safe for nearly everybody who takes them. What's more, most doctors will try somebody suffering from anxiety on an SSRI (often more than one SSRI, not at the same time though of course) BEFORE putting them on a Benzodiazepine, because SSRIs are a TRILLION times safer & less addictive & all that than Benzos are. It's true that one SSRI (Paxil) has been known to cause withdrawal that tappering cannot avoid in about 30% of the people who take it, & somewhat severe withdrawal in less than 10% of the people who take it (not withdrawal anywhere NEAR as bad as Benzo withdrawal)... & Paxil's pretty much never prescribed anymore for that reason. I've gone off of Zoloft cold-turkey at least five times (cold turkey from the maximum prescribed dosage, at that) & noticed absolutely NO withdrawal symptoms.
Fifth -- "benzos which are more dangerous with dependence and are used long term all the time." ... Actually, they're really not used long term all the time at ALL, & usually when somebody is prescribed Benzos for an extended period of time they're prescribed it as a PRN, & are given like 30 pills that are supposed to last them months. Most doctors try everything on someone with Anxiety before giving them even Klonopin. Basically, doctors putting people on Benzos long term is a last-resort type thing, & usually they initially don't intend for the person to be on it long term. Also, people on Benzos long term are usually the types of people who suffer from such bad anxiety that it's crippling.
Sixth -- "however amphetamines are given for resistant depression" ... Not in the US they're not.
Seventh -- "and even though they're addictive they won't cause physical dependence." ... "Addiction" generally entails physical dependence. More importantly, though, what the hell do you mean Amphetamines don't cause physical dependence? Of COURSE they do. People sometimes go out of their fucking MINDS from Amphetamine withdrawal.
Eight -- " but still opioids need to be looked into for the treatment of depression." ... They have been looked into very thoroughly in regards to their potential as effective treatment for Mood Disorders, & they're
continuing to be looked into for that purpose today.