http://www.nytimes.com/2011/07/17/us/17salts.html?_r=2&hp
http://www.erowid.org/chemicals/mdpv/mdpv.shtml
MDPV is a stimulant drug legally available in some of the States.
"The primary psychological effects have a duration of roughly 3 to 4 hours, with after effects such as tachycardia, hypertension, and mild stimulation lasting from 6 to 8 hours.[1][10] High doses have been observed to cause intense, prolonged panic attacks in stimulant-intolerant users,[1][10] and there are anecdotal reports of psychosis from sleep withdrawal and addiction at higher doses or more frequent dosing intervals.[1][10] MDPV has been distinguished by some for its powers as an aphrodisiac.[1] It has also been repeatedly noted for inducing strong cravings to re-administer.[10][12] Users have reported a compulsive desire to continuously re-dose, even following onset of the unpleasant side effects induced by prolonged use and higher doses.
Extended binges on MDPV have also been reported to produce severe comedown syndrome similar to that of methamphetamine[citation needed], characterized by depression, lethargy, headache, anxiety, postural hypotension (lightheadedness and weakness of the muscles), and in some cases severely bloodshot eyes, which usually subside within 4 to 8 hours. MDPV may also cause temporary bruxism. Side effects are highly dose-dependent. No fatalities have so far been reported without the combination of other substances except for suicide.[1]
Reported modalities of intake include oral consumption, insufflation, smoking, rectal and intravenous use. It is supposedly active at 3–5 mg, with typical doses ranging between 5–20 mg.[1] MDPV loses potency when it is put into solution."