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Vascular constriction

C

Cybion

Bluelighter
Joined
Feb 24, 2010
Messages
233
Hey PD,

I have obtained a little bit of Bromo-dragonfly (DOB-DFLY) I don't have enough here to overdose even if I tried but there's one thing that keeps troubling me about this substance: Vascular Constriction.

My question is thus: what would be something that could counteract any vascular constriction? I'm sure it's nothing that I really have to worry about with the amount that I have (1mg of the less potent isomer) but I like to be careful when exploring such new territory.

Thanks

Cybion
 
^^Ummm pretty sure hot lemon water is not going to help lower your blood pressure throughout your body by relaxing the walls of your blood vessels very much. Maybe a tiny bit in the neck?

I'm not sure of any other than nitro for angina myself though sorry. I think booze will have this effect as well now that I think about it. Just google vasodilators and see what you get :D
 
For aches and pains related to vasoconstriction you want a skeletal muscle vasodialator. Booze only opens up the vessels in the skin and boner meds are smooth muscle vasodialators. Unfortunately, it looks like most drugs that might actually be powerful enough to mitigate the vasoconstricion of vasoconstricting psychedelics are smooth muscle vasodialators (for hypertension). These later drugs may save your life with something like BDFLY but I don't think they'll get rid of those muscle aches that can sometimes ruin a trip.

Nitric oxide supplements (esp. the mixes of numerous compounds), creatine, natural means of increasing insulin (which is a skeletal muscle vasodialator), and just getting up and exercising prior to dosing are the best candidates I've found for avoiding annoying psychedelic vasoconstriction, but I'm not sure they'll really stand up to things like BDFLY, LSD, or mephedrone. Not to mention who knows how they might interact? You can find some of these online on body building supplement sites if you're inclined to try them. They're sold to help body builders increase their "pump."

Here's an article on increasing insulin:
http://webcache.googleusercontent.c...muscle+vasodialators&cd=9&hl=en&ct=clnk&gl=us

EDIT: Like amapola above, I also thought of booze, but apparently it only dilates the the capillaries in the skin.
 
Last edited:
thanks, I appreciate the responses. cayenne pepper sounds delicious lol.
 
Cybion said:
thanks, I appreciate the responses. cayenne pepper sounds delicious lol.
Click to expand...

"One of the most dramatic health benefits of cayenne pepper is its reported ability to stop a heart attack in its tracks! This effect comes from the ability of cayenne to act as a vasodilator and open arteries allowing critical blood flow to the heart to resume."

not sure on dosage, but swallow a capsule maybe like 500mg
 
^From what I can find cayenne pepper is only a smooth muscle vasodialator, so while it is advisable to take in to prevent, for instance, having to amputate your fingers due to BDFLY vasoconstriction, I'm not sure how much it'll help with the more common vasoconstriction related discomforts.
 
I would avoid drink alcohol as it can raise your blood pressure, which contributes to hypertension, which is a no no with vasoconstrictors.
 
Anybody have thoughts on mild blood thinners being good or bad?

Given the predisposition towards hypertension during BrDrFLY trips, maybe it might be a good idea to avoid blood thinners, so that in the rare, unfortunate chance that a embolism or stroke occurs, it is not bleeding out, and the normal coagulative process can take place.

On the other hand, perhaps a bit of aspirin or something can make the RBCs pump easier through the constricted veins...

Thoughts?
 
blood thinners do cause not vasodilation, nor will help with anything but preventing a clot from forming. Blood thinners over all work on different aspect of clot formation, but the prevention of platelet aggregation (NSAIDS), and the halting of various process involved in the production of clot (Warfarin), will not help at all with preventing the side effects of vasoconstriction.

Thinning the blood is not something you want to mess around with especially with out proper medical supervision.

(I used to be on blood thinners)
 
Cannabis lowers blood pressure and works as a vasodilator by relaxing the walls of the arteries. If you're familiar with it and don't get panick attacks on it, it won't act as a vasocontrictor.
 
Oddly enough, I don't smoke Cannabis, which a lot of people bust on me for but I just find it silly in comparison to most Psychedelics.

I agree, I don't think thinning the blood would be the best route to follow, it's kind of like doing thing B in hopes it will help thing A. It seems like a much better thing to just do the exact opposite of thing A. Which of course in this case is the constriction
 
Exactly. In this case B can be potentially deadly, or at least extremely trouble sum during a psychedelic experience. Take it from me, whenever I would get a cut it would take a minimum of 10-15 minutes for it to stop bleeding. This is including simple cuts like a ripped cuticle, or even a paper cut. Not something you want to deal with while tripping. It suck enough as it sober, let alone high on weed. Also, we don't know about the potential interactions that bromo-dfly might have. Blood thinners are not something to be messed with, and combining it with RCs is pretty reckless.
 
I've looked around 'natural vasodilators' and there seems to be a lot of crap or at least not acute enough acting ideas. I mean celery? That being said the only thing that really stands out is increasing your potassium (lower sodium) and increase magnesium (lower calcium). No time to look into anymore now but I shall unless someone beats me to it. Could be extremely beneficial for LSA as well.
 
Ginkgo Biloba extract? I believe it acts as a systemic vasodilator, not just in the brain? Also a very potent antioxidant, so probably good to be on along with any drug binge, haha. It can also be a mild blood thinner, so I would suggest no more than the standard 60mg/2X-per-day dose beginning for some days at least before the Br-DrFly.
 
Just Googled "ginkgo vasodilation" and got these listings among others:

Effects of Ginkgo biloba extract on blood pressure and vascular ...
by Y Kubota - 2006 - Cited by 9 - Related articles
We previously demonstrated that Ginkgo biloba extract (Ginkgo) produced vasodilation via the nitric oxide pathway in aortic segments isolated from Wistar ...
www.ncbi.nlm.nih.gov/pubmed/16451753 - Similar

Ginkgo biloba extract improves coronary blood flow in patients ...
by Y Wu - 2007 - Cited by 9 - Related articles
Ginkgo biloba extract (GBE) has well-documented cardioprotective effects on ...
www.ncbi.nlm.nih.gov/pubmed/17564952 - Similar

Vasodilator
Several vasodilators are considered specific for coronary arteriodilatation, particularly Crataegus spp. (Hawthorn) and Coleus forskohlii (Coleus). Ginkgo ...
home.caregroup.org/clinical/altmed/.../Vasodilator.htm - Cached - Similar

Diagnose-Me: Treatment: Ginkgo Biloba
One effect of Ginkgo extract is that of promoting vasodilation and blood flow, thus providing a therapeutic effect on cognitive disorders and high blood ...
www.diagnose-me.com/treat/T7890.html - Cached - Similar

High Blood Pressure: Lower Your Blood Pressure And Reduce Your ...
Nov 30, 2010... a natural vasodilator (a substance that widens your blood vessels) (Brit. ... The herb Ginkgo biloba is known to increase blood flow by ...
www.thehealthierlife.co.uk › ... › High Blood Pressure - Cached - Similar

GINKGO THINK - Healtheries. Feel good from the inside out.
Ginkgo biloba causes vasodilation and therefore increased circulation. It enhances ATP synthesis and increases cellular glucose uptake increasing energy ...
www.healtheries.co.nz/page.php?id=25&prod=49 - Cached - Similar

Vasodilator: Herbs than open and expand the blood vessels Herb ...
Vasodilator: Herbs Than Open And Expand The Blood Vessels ... Leaves and Nuts : China : Today gingko is one of the most commonly prescribed herbs and is a ...
www.anniesremedy.com/chart.php?prop_ID=92 - Cached - Similar
 
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