Site Feedback Update ‘Lysergamides’ prefix to the new term

[red22]

There are three main ergot alkaloid classes, clavines, ergoamides (lysergamides), and ergopeptides, with 3 belonging to the ergoamide class.

Biosynthesis and synthetic biology of psychoactive natural products. CS Jamieson, J Misa, Y Tang, JM Billingsley. Chem. Soc. Rev., 2021,50, 6950-7008. DOI: 10.1039/D1CS00065A (2.5 Lysergic acid and LSD)

Note that the '3' that is mentioned refers to the three natural ergoamides.


I think lysergamide has a sloppy feel. Sounds like something you’d hear on Nickelodean. Makes me think of someone slurping a beverage.

 

[deficiT]

There are three main ergot alkaloid classes, clavines, ergoamides (lysergamides), and ergopeptides, with 3 belonging to the ergoamide class.

Biosynthesis and synthetic biology of psychoactive natural products. CS Jamieson, J Misa, Y Tang, JM Billingsley. Chem. Soc. Rev., 2021,50, 6950-7008. DOI: 10.1039/D1CS00065A (2.5 Lysergic acid and LSD)

Note that the three that is mentioned refers to the three natural ergoamides.


I think lysergamide has a sloppy feel. Sounds like something you’d hear on Nickelodean. Makes me think of someone slurping a beverage.

Not sure what the question is here, you're asking us to change the Lysergamides prefix in Psychedelic Drugs to a different term?

 

[red22]

Yes.

 

[deficiT]

Yes.

I can tag the PD mods here to see what they think, but personally I don't see a reason to change it. Lysergamide is the term that most people will recognize, as far as I know about it

 

[deficiT]

@arrall @Cheshire_Kat @JackARoe @Didgital @Pfafffed

 

[Cheshire_Kat]

There are folks here that have many levels of awareness of the subject. Some are just acquainted with street names and some are very proficient in chemistry and neurology. There is room on Bluelight to accommodate all these levels depending on which sub forum the posts may present themselves. The proposed term might be more appropriate in Neuroscience and Pharmacology Discussion than in say Drug Experiences, Trip Reports and Psychedelic Drugs, depending on the particular user's level of knowledge.

I think that alternative TAGs like the one @red22 proposed should be available, but I stop short of replacing it outright so that everyone can express themselves comfortably.

 

[Didgital]

I have never in my life heard the term "ergoamide". However I can see without looking why it could be used. However, it is too general because it would include both Lysergic acid amides (lysergamides) and ergopeptides which are ergoline(s) linked to a tripeptide via an amide group. AFAIK, no one on bluelight or anywhere for that matter are trying to get high from consuming ergopeptides (aside from Krystal Chole, Leonard Pickard, and Gordon Todd Skinner; who all supposedly drank ergot wine)

So I don't really see a reason to distinguish between the two classes.

Note that the three that is mentioned refers to the three natural ergoamides

None of the clavines even posess an amide functional group, so how are they even ergoamides?

Ergoline - Wikipedia

en.wikipedia.org

Agroclavine - Wikipedia

en.wikipedia.org

Elymoclavine - Wikipedia

en.wikipedia.org

Festuclavine - Wikipedia

en.wikipedia.org

And their role in psychoactivity is unknown or they're known to be toxic.

I think lysergamide has a sloppy feel

Because you personally think that a word has a sloppy feel, even though it's been used by millions of people for decades and it's scientifically descriptive, that we should change the term to one that almost no one uses or has heard of?

All of the commonly discussed ergot compounds on bluelight (LSD, AL-LAD, MIPLA, LSA etc) are derivatives of Lysergic Acid. And they're amides, so lysergamide is a totally understandable term.

I don't know of a single post on BL about anyone consuming ergolines/clavines. I don't know of anyone besides myself that even posesses pure clavines. Nor do I know of anyone seriously discussing consumption of ergotamine (ergopeptides).

So my answer would be "Gtfo. No. Do not change or remove the Lysergamide tag. Why reinvent the wheel"

Lastly, while the paper you linked is very informative, even they don't mention the terms ergoamide or clavine, so I'm not sure why it's relevant to the point you're trying to make? After googling ergoamide, I can only find 2 papers that use that term.

 

[MedicinalUser247]

Well... Digitals all about the technical stuff. Hmmm... I wonder about his personal usage.