'Tis the Season for Hangovers: Why Do They Hurt So Bad?

AfterGlow

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Monday, December 22, 2008

Pounding headache, dry mouth, red eyes, fuzzy memory — the pain of a hangover is familiar to many. But why does alcohol make us feel so good and then so bad? Even though human beings have suffered from hangovers for thousands of years, we're still largely in the dark as to exactly why they happen, and how to cure them. Researchers say many hangover cures simply don't work. The only sure-fire cure, they say, is not to get drunk in the first place. If only it were that simple. Here is what scientists believe takes place in the body after a big night out on the town.

Headache: Scientists believe that those throbbing, relentless hangover headaches are due to a number of factors. The first is dehydration. Alcohol prevents the release of a hormone responsible for retaining water in the body. As a result, the kidneys no longer conserve water and more fluid is excreted as urine. Moreover, alcohol widens the blood vessels in the head, adding to the pain.

Concentration: Avoid any task that requires more than half your brain. Studies suggest that hangover misery interferes with both short-term memory and concentration. One study of military pilots revealed that flying ability was still impaired eight to 14 hours after drinking, especially in older pilots. Some studies suggest that dehydration might be to blame, while others believe that acetaldehyde, a product of alcohol breakdown, may have an impact, along with sleep deprivation. Despite alcohol sending us to sleep, it worsens the quality of our shuteye, leaving people incredibly tired in the morning.

Mood: The world is usually not a happy place when you awake after a big night. Hangovers increase depression, anxiety and irritability. Scientists are still unsure exactly how alcohol exerts its mind-bending affects, but believe that it is a combination of sleep deprivation, a lack of serotonin — a mood-enhancing chemical in our brain — and an alcohol-induced drop in blood sugar. And the dizziness and light-headedness? Also due to dehydration, say researchers.

Eyes: A telltale sign of a heavy night, eyes become puffy, sore and bloodshot. Alcohol causes blood vessels in the eyes to dilate and dehydration leaves them feeling dry.

Mouth: The mouth and throat feel dry, furry and generally disgusting. This is caused by dehydration and is worsened by smoking.

Nervous system: As anyone knows who has passed out after a night of drinking knows, alcohol is a sedative. But to make sure that we don't slip into unconsciousness, our nervous system steps up a gear and becomes more alert. When the alcohol leaves our body, however, the nervous system remains in a hyperactive state, leading to sweating, shaking and sensitivity to light, sound and touch. Further, sleep deprivation can aggravate these symptoms.

Heart: Heart rate increases, possibly as a result of alcohol interfering with the body's nervous system. Long-term alcohol abuse can lead to cardiomyopathy — damage to the heart muscle.

Liver: Alcohol cannot be stored in the body and so is broken down in the liver. In this two-step process, alcohol is turned into acetaldehyde, which then becomes acetate. However, this process is slow — one unit of alcohol is metabolized every hour. It is widely believed that acetaldehyde may contribute to the misery of the hangover, as accumulation in the blood causes rapid pulse, sweating, skin flushing, nausea and vomiting. Some people lack a molecule that breaks down this compound and become ill soon after drinking. Further, alcohol metabolism leads to an accumulation of fatty compounds in the liver and lactic acid in the body fluids. These inhibit glucose production, leading to low blood sugar.

Body temperature: Ever felt a bit hot under the collar when you're suffering with a hangover? Alcohol may interfere with the production of hormones that control the 24-hour body clock, leading to body temperature being abnormally high.

Stomach: Alcohol irritates the stomach lining and delays it emptying, leading to nausea and vomiting.

Muscles Everything is an effort when you have a hangover. Muscle weakness and general fatigue are a result of low blood sugar and dehydration. The latter, together with an accumulation of lactic acid from alcohol metabolism, can cause foot and leg cramps.

Click here to read more on this story from the Times of London and to learn how to alleviate some of the pain of a hangover.

link
 
Good read, explains allot about how i feel right now, although alcohol is one of the more "Easier" hangovers i have experienced with drugs, it definitely leaves me feeling pretty haggard afterwards. I Ususaly pop a couple of Tylenol extra strength and it takes that headache right away. Good thing i don't have to work today though!
 
^ Yer best to take Ibuprofen after a night of drinking instead of Paracetamol due to hepatotoxicity.

But yea, good article :)
Far too many people drink and don't know what is actually is going [on] in their bodies.
Which just seems weird to me. If I'm gunna put a chemical in my body, I wanna know exactly what it's going to be doing.
 
Funny, I always though that the pounding headache was the reflection of the numerous brain cells being killed off %)
 
^ Yer best to take Ibuprofen after a night of drinking instead of Paracetamol due to hepatotoxicity.

Although I generally agree with this (Oh my poor, poor liver), don't forget that Ibuprofen AND aspirin are pretty caustic to the stomach. I've known several people to get stomach issues and even ulcers from too much drinking/NSAIDs.
 
Anyone know why drinking a beer or two relieves the hangover? Only to bring it back a few hours later of course...I always thought the hangover was partially withdrawal effects, though this was when I was a fair bit younger, and as a now established drug user this doesn't seem very likely at all. Still, the ultimate hangover cure, being Alcohol itself, tells me it may have to do with a lack of Alcohol in the system causing the hangover. Can anyone explain this further, as it was a belief of mine, that I no longer really believe, though some evidence tends to suggest it is true.

Man I'm drunk.
 
man this is my third day drinking and i dunno how to stop. alcohol is so readably available and now im waiting for my third day hangover. Drinking is probably my worst addiction, but i cant shake it. At least now i know what is what that makes me feel like shit, although i cant abandon it. Good thing its legal cuz i don't know whats next.

loss of all inhibitions WHOOOOOOOOOO
 
Although I generally agree with this (Oh my poor, poor liver), don't forget that Ibuprofen AND aspirin are pretty caustic to the stomach. I've known several people to get stomach issues and even ulcers from too much drinking/NSAIDs.

A bit of food sorts that out just fine :)
As long as you eat something beforehand, and don't take any more than 400-600mg, your tummy should be alright.
 
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