The worst opiate/opiod to withdraw from? [New poll options added 1-22-08]

[Jabberwocky]

if i could change my vote to fent, i would. that shit is intense and by far the worst wd's albeit short. feels bad man

 

[DexterMeth]

^seriously? fent more so (in the short run, how I was talking about in my previous post) over hydromorphone? Perhaps I don't have enough experience with PROLONGED exposure to daily fent to arrive to your personal conclusion...then again, like I said before, this is a very subjective post/original question being asked.

FYI - fentanyl was the one opiate (aside from a little morphine; it was IV fentanyl citrate from an ampule btw ), that gave me my worst OD by far, ever...I don't think the completely irresponsible GBL use that got way out of hand helped at all either though 8)

 

[Georgie25]

From the opiates i have w/d'd from : heroin and oxy: i'd say oxy was worst.

 

[Jabberwocky]

^seriously? fent more so (in the short run, how I was talking about in my previous post) over hydromorphone? Perhaps I don't have enough experience with PROLONGED exposure to daily fent to arrive to your personal conclusion...then again, like I said before, this is a very subjective post/original question being asked.

FYI - fentanyl was the one opiate (aside from a little morphine; it was IV fentanyl citrate from an ampule btw ), that gave me my worst OD by far, ever...I don't think the completely irresponsible GBL use that got way out of hand helped at all either though 8)

i've never used dilaudid unfortunately...maybe fortunately haha.

ive been dependent on opiates for some time now, just recently changing from bupe to fent for pain and i'd take bupe wd's anyday over fent. morphine was pretty harsh as well as oxy, but nothing has compared to fent so far. though my wd's have been getting a lot more harsh lately because of my prolonged use.

fents reasonably short lasting (though, i dont fully know yet because my dr gave me a shot of morph to help me out today) so that's one good thing compared to the drawn out process of bupe.

 

[-Guido-]

Thanks for the quick reply Rorschach.QUOTE]

Your welcome.

 

[Musmaro]

Methadone, hands down. Worse than the withdrawals from even my worst heroin binges. I felt like I was gonna die during my methadone withdrawals, got back on heroin.

 

[pukingcells]

I have to agree..... Methadone.
I was using both Methadone (120 mgs) and Heroin (at least a daily bundle) and went into detox. There was basically nothing they could do for me as far as relief, but I am getting off topic, I was suffering from the methadone withdrawal up to 6 weeks later. Just when I thought I had rounded the corner, BAM I would be flat on my back again, sick. I couldn't move, I puked almost daily. I couldn't eat, sleep or function. It is so long an drawn out that I could understand why most would return to using

 

[TJ5]

Fucking tramadol! Worse than kickin smack or other painkillers

 

[mdmantpa]

^ wow...

 

[Candy_Raver]

I'd have to say Opana(oxymorphone) after a two week binge of IVing the 10mg instant release pills, I ran it though a cotton then 0.2 micron filter, I was literally in hell for 3 days. Worse than binging on OCs everyday for 3 weeks, and followed after that was a 1 and a half week binge of morphine. I rarely touched heroin, as tar is so dirty, so I have nothing to compare to that.

-PLUR

 

[dopeman]

I have to say Methadone is the absolute worst. I was on 160mg a day and went to jail for 6 months. It took 5 days before they would even give me medicine to make me stop throwing up and the only reason they did that was because I was dehydrated. I was not well for over a month and not right for several months.

 

[stonedandrolling89]

The most severe w/d's I've been through were thanks to OxyContin. I quit cold turkey on May 16th, 2008, and my daily dosages before quitting ranged anywhere from 80mg(to keep from being sick, mostly) to 240mg. I was also using a lot of morphine at the time, as well.

I was physically sick to the point of not being able to move from laying down to sitting up without vomiting, was sweating profusely, and felt the worst I've ever felt in my life for a little over a week. The depression and lack of motivation lasted for about a month and a half, almost two months.

 

[HighonLife]

i voted oxy b/c i have never WD'd from heroin or methadone or even used either,

Oxy WD's i had sucked but were not as bad as others, im sure, as i didnt have a major habit, i did use daily for a month using 40-80 a day depending on ROA

also stopped a 3 week HyMo binge that sucked but i felt the oxy WD was worse but in all honesty the preceeding Oxy use was more intense then the HyMo use

 

[JustaChippa]

I have only ever withdrawn from hydro, and thus have nothing to compare it to. It was definitely bad enough!

My habit was fairly long-term, however, (5+ years), and on the heavy side, (it varied, but probably 80-120 mgs. of hydro in a 24 hr. period on average.)

 

[adifferentcity]

Methadone. i never knew pain like that even existed.

i found heroin was worse than oxy. but nothing compares to the excruciating ceaseless agony of 'done WD.

 

[Dr Links]

I've been on opiates for over ten years now and I made the worst mistake of getting on methadone 3 years ago. I had surgery after surgery so the dope usage continued to escalate. By my tenth surgery, I thought 240mg of parenteral dilaudid/day plus 180 actiq 1600mcg suckers per month was a bad habit but I was wrong, boy was I wrong. I went to Hazelden and managed to kick the habit that they didn't believe was real, until the Qwest assay came back. It was the hardest thing I'd done to that point in my life but after 18 days w/o sleep, but I finally did. I started to feel better and stayed drug free for 6 months, white knuckling it and resisting 12 step meetings and the whole recovery bit. My knee pain was becoming more and more of a problem and the addict in me justified my wonderful decision to start methadone. Ob ovo (at the beginning), I found it to be an amazing painkiller b/c of its' fantastic longevity. However, it's the ridiculous half-life that makes it such a montser to kick. I'm now stuck on 300mg of methadone per day and really want to stop b/c I am producing ZERO testosterone and the law of diminishing returns is just pummeling me. I tried kicking cold turkey nine months ago with tons of alprazolam, vistaril, soma, clonidine, and cannabis. I ended up seizing on day 15 and ended up in the ER, not b/c of my detox protocol, but from trying to stop such high doses of methadone w/o a reduction plan. I was told by the attending doc that I absolutely MUST taper by 10mg/month. Did you know that Hazelden won't even accept a patient on methadone unless they've cut down to 30mg/day. Not to mention the fact that the oral bioavailability of methadone ranges about as much as any drug possibly can. It's half life ranges from 10-190 hours! That's the reason they pulled the 40mg Methadose tabs off the market. Someone whose opiate naive may take a 40mg diskette and b/c of his/her DNA, they metabolize 90% of it and that 36mg dose results in an tragic fatality. I've been toying with the idea of going back on fentora, actiq and duragesic (I'll need insane quantities in order to switch but I know I can kick such a short acting opiate that is ONLY a mu agonizing opiate). Fentanyl w/d is intense and horrible, don't get me wrong, but it doesn't compare with methadone. Post acute withdrawal will suck from where I'd be sitting, but it's better than acute w/d that lasts just as long and doesn't even start until about 3-4 days in. Methadone w/d takes literally months, not 5-10 days of hell, I'm talking about up to half a year (depending on how long you've used and how much you take and how old you are((the younger you are, the more resilient and elastic your limbic system is)).) I'm a pharmacology major so I can kind of explain what's going on with methadone w/d compared to semi/synthetic dope w/d like dilaudid, oxycontin, opana, etc. Methadone is not just a potent mu agonist, it's also an extremely potent kapppa agonist and it doesn't end there. It's a potent NMDA antagonist (N-methyl-D-aspartic acid) and is crucial in regulating cortisol and glutamate transference. Glutamate is the antithesis of GABA so in lamens' terms it's the excitory neurotransmitter responsible for jacking people up during the fight/flight response and making them esp. restless and unsettled during w/d. It then floods your system with cortisol which is a stress chemical that green-lights antagonization of corticotropoin releasing hormone, CRH, which is crucial for warding off anxiety and boosting seratonin. So when one quits methadone, they aren't just kicking an opiate, they're kicking a serious antidepressant and anxiolytic. Tramadol, brand name Ultram, is like baby methadone b/c it's not just a partial mu opiate agonist, it's also a potent SSRI + SNRI and its' w/d profile is similar to methadone but much, much less treacherous. I didn't mean to throw my life story into this simple survey, I apologize, but I certainly think methadone should be re-named methadont.

 

[JediMind]

Ive kicked most of those substances at one point or another.....except the Methadone.

I could never see the logic in trading a habit I can kick in a week for one it takes 3 weeks at least to withdraw from. (see above post)

In my 20+ yr opioid career, 150ug Fentanyl every 2 days was my hardest kick. That was the base drug , I also was taking upwards of .5g of Oxy a day for "pain control" after a near-fatal rollover wreck.
I checked into detox and I couldnt even stop dry-heaving long enough to give my information. They wouldnt give me a bupe dose until it had been 48 hrs since I peeled the last patch off, so the first night...I thrashed so violently in that bed, my knees and elbows were bloody from flopping around.

Im not trying to shit on anyone else's opinion, but I'll kick street dope 100x before I run a fent habit again.

 

[arthunter888]

Why aren't people mentioning Opana/oxymorphone, and it's not even on the list? I haven't been through this WD but it seems like it would be quite a nasty one given its potency and euphoria level.

 

[azbat1]

I've been taking Morphine and Oxycodone for about 8 years now for pain. I'd like to quit because it messes with my sex life. Does anyone have any suggestions? Am I looking at months of agony?
Az

 

[drunken_etard]

I have been through Methadone, Oxycodone, Morphine WD all at different times. I thought that the Oxycodone was the most intense but shortest. The methadone was overall the worst because it was so damn long. Morphine was the least worst.

All 3 times I was sucessfull at quitting too.