Deinonychus
Bluelighter
- Joined
- Oct 20, 2012
- Messages
- 401
Hey everybody! So I've been wondering for a while why Shulgin chose the N,N-diallyltryptamines (DALT, 5-MeO-DALT, their analogues) as the focus of his recent research. It's certainly not fully psychedelic, but that's neither good nor bad, just different compared to the focus of his research in the old days (P and TIHKaL compounds). I know he was going to publish another book about the DALTs, but I don't know what the status of that project is since the good doctor is now very unfortunately suffering physical and mental health issues.
Has anybody ever seen or heard any explanation of the choice of the diallyltryptamines? And if not would anybody like to hazard a guess as to why he picked those and not other more fully psychedelic compounds such as the flies or N-benzyl PEA derivatives?
One thing I can think of is that perhaps he wanted to focus on compounds that he had conceptualizer, instead of just elucidating the activity of Nichols' compounds in more detail. That's not to say that there's any bad blood between them, on the contrary I believe they are well-acquainted, but back to the point perhaps he wanted to explore things that were 'his'? That's just a wild guess, I really don't know.
Is there some sort of SAR that he was aiming for with the diallyltryptamines that is contrary to expectations in the manner of the theoretical island of stability in the superheavy elements? Like a particular substitution of DALT that restores full psychedelia despite the long chains on the nitrogen, analogous to the half-lives of superheavy elements possibly increasing for a few elements due to filled orbitals even though the heaviness should make the half-lives continue to decrease.
Anyway this is just something I've been a bit curious about for a while, so I decided to see if anybody has any answers regarding the motivation for choosing diallyltryptamines for his most recent work. And to be clear, while 5-MeO-DALT sure isn't my thing, since I prefer full psychedelia, I'm not knocking it by claiming it to be less than fully psychedelic. That's just a subjective observation/opinion, not a value judgement.
Cheers
D
Has anybody ever seen or heard any explanation of the choice of the diallyltryptamines? And if not would anybody like to hazard a guess as to why he picked those and not other more fully psychedelic compounds such as the flies or N-benzyl PEA derivatives?
One thing I can think of is that perhaps he wanted to focus on compounds that he had conceptualizer, instead of just elucidating the activity of Nichols' compounds in more detail. That's not to say that there's any bad blood between them, on the contrary I believe they are well-acquainted, but back to the point perhaps he wanted to explore things that were 'his'? That's just a wild guess, I really don't know.
Is there some sort of SAR that he was aiming for with the diallyltryptamines that is contrary to expectations in the manner of the theoretical island of stability in the superheavy elements? Like a particular substitution of DALT that restores full psychedelia despite the long chains on the nitrogen, analogous to the half-lives of superheavy elements possibly increasing for a few elements due to filled orbitals even though the heaviness should make the half-lives continue to decrease.
Anyway this is just something I've been a bit curious about for a while, so I decided to see if anybody has any answers regarding the motivation for choosing diallyltryptamines for his most recent work. And to be clear, while 5-MeO-DALT sure isn't my thing, since I prefer full psychedelia, I'm not knocking it by claiming it to be less than fully psychedelic. That's just a subjective observation/opinion, not a value judgement.
Cheers
D
