I imagine the maze of regulatory agencies you'd have to go through would be for all practical purposes impenetrable. I do know the Auburn University Pharmacology Dept has done work on detecting various cathinones in urine and distinguishing them from other MDxx type drugs in various types of analyses, but insofar as any legitimate human bioassays, not that i'm aware of.
Also, 4-Aco-DMT is one of the few that's been specifically listed as an analogue in the U.S., during some of the litigation pursuant to Operation WebTryp, so it technically, is illegal. Also, its the acetate ester of psilocin, which would make it fit quite well with the U.S. legislation, unfortunately.
I've thought about this quite a bit myself, and I doubt it would be possible at the moment. If you wanted to study its effects you could find a community of users and distribute surveys, but that's probably about it.