nuke
Bluelighter
- Joined
- Nov 7, 2004
- Messages
- 4,191
Nuke again,
This was recommended recently and I think could be a positive addition to ADD.
In this thread we will contribute short summaries of recent articles related to drugs, licit or illicit, such as biochemistry, psychopharmacology or botany. I'd encourage you to simply head to the websites of your favourite journals and browse their indexes or just to search on pubmed about topics that interest you.
I think the following format will lend well to keeping the contents of this thread organized:
1.) Title of work
2.) Authors
3.) Journal and issue number
4.) DOI reference with URL link to the article
5.) Abstract in quotes
6.) Your hopefully minimum one paragraph review commenting on your reading of the full-text article and anything exciting or fascinating you found within it.
7.) Optional: Attached pictures of some of the figures from the article
If you are having trouble accessing full-texts of papers, I would recommend you head to the local university with a flash drive and pick up whatever you want.
I would like to keep all articles within the range of the past 24 months, to keep everything recent.
--------------------------------------
Rules for sharing journal articles by Epsilon Alpha:
Several mods and users have brought up the idea of having a procedure of sharing of journal articles, and me and two of the other ADD mods have discussed this topic. As such, this is an experimental procedure to see how full text requests work out. Please leave comments/suggestions in this thread, we will do our best to make this as effective as we can; this is an experiment after all
Rules
Request Format
Please link the pubmed or respective hosting service as well as post the abstact in a quote.
Example:
This was recommended recently and I think could be a positive addition to ADD.
In this thread we will contribute short summaries of recent articles related to drugs, licit or illicit, such as biochemistry, psychopharmacology or botany. I'd encourage you to simply head to the websites of your favourite journals and browse their indexes or just to search on pubmed about topics that interest you.
I think the following format will lend well to keeping the contents of this thread organized:
1.) Title of work
2.) Authors
3.) Journal and issue number
4.) DOI reference with URL link to the article
5.) Abstract in quotes
6.) Your hopefully minimum one paragraph review commenting on your reading of the full-text article and anything exciting or fascinating you found within it.
7.) Optional: Attached pictures of some of the figures from the article
If you are having trouble accessing full-texts of papers, I would recommend you head to the local university with a flash drive and pick up whatever you want.
I would like to keep all articles within the range of the past 24 months, to keep everything recent.
--------------------------------------
Rules for sharing journal articles by Epsilon Alpha:
Several mods and users have brought up the idea of having a procedure of sharing of journal articles, and me and two of the other ADD mods have discussed this topic. As such, this is an experimental procedure to see how full text requests work out. Please leave comments/suggestions in this thread, we will do our best to make this as effective as we can; this is an experiment after all
Rules
1) Do not post direct links to the paper, you can post that you are willing to send PM's of a specific paper(s) though.
2) Do not discuss the paper in the thread, make a separate thread or a relevant existing one to do so. This is to maintain an easily navigable request forum.
3) If you also would like the full text to a previously requested paper please PM the user who claims to have the fulltext or the user who requested it rather than post in the thread, however if you do not receive an answer within a reasonable time frame (~1 week) you can post a reply.
Request Format
Please link the pubmed or respective hosting service as well as post the abstact in a quote.
Example:
Chronic treatment with curcumin enhances methamphetamine locomotor sensitization and cue-induced reinstatement of methamphetamine self-administration.
Zhao C, Lou Z, Zimmer B, Yu Z, Li P, Ma B, Sun Y, Huang K, Zhou W, Liu Y.
Source
Ningbo University School of Medicine, 818 Fenghua Road, Ningbo, Zhejiang 315211, PR China.
Abstract
OBJECTIVES:
Curcumin, a major active component of Curcuma longa, possesses antidepressant effects that are mediated by the 5-HT system. However, little is known about the effect of curcumin on the behavioral consequences of methamphetamine (METH).
METHODS:
The subjects were male, adult Sprague-Dawley rats. In Experiment 1, the effects of 20 and 40 mg/kg curcumin (i.p.) on response rates and breakpoints of 0.06 mg/kg/infusion METH were evaluated. In Experiment 2, rats were self-administering METH for 10 days followed by a 14-day abstinence period. During the abstinence period, the animals were treated with DMSO, 20 or 40 mg/kg curcumin. All rats were then tested for extinction responding and cue-induced reinstatement. In Experiment 3, rats were treated with DMSO, 20, or 40 mg/kg curcumin 15 min before a METH-induced locomotor activity test for 14 consecutive days. In Experiment 4, rats were pretreated with DMSO or curcumin (20 mg/kg or 40 mg/kg) for 13 days and were subsequently tested for METH-induced locomotor activity on the 14th day. In Experiment 5, three groups were tested for locomotor activity after an injection of DMSO, 20, or 40 mg/kg curcumin. The test was repeated for 14 days.
RESULTS:
Curcumin produced little effect on response rates and breakpoints maintained by METH. Chronic treatment of only 40 mg/kg curcumin during the abstinence phase enhanced cue-induced reinstatement of METH self-administration. Chronic administration of curcumin increased METH-induced sensitization of locomotor activity at the lower (20 mg/kg) but not higher (40 mg/kg) dose. However pretreatment of curcumin alone showed no significant effect on acute locomotor responses to METH and locomotor responses per se.
CONCLUSIONS:
Curcumin enhanced, rather than inhibited the behavioral effects of METH.
Copyright © 2012 Elsevier Inc. All rights reserved.
PMID: 22750063 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/22750063
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