Dissolving tab in water has always worked for me. I use one of those larger dark amber glass dropper bottle for this purpose. I would leave it for a day or two, then shake it up and use a dropper to dose. In the past I've gone through more than 3 months of non-stop daily microdosing of about 1.3-1.5 tab a week (calculating average of 70-100mcg per street blotter LSD and about 20mics a day).
At first I felt super awesome - smart, imaginative and very understanding. I loved the energy push, the feeling of "righteousness", loads of creative ideas. After a while I started having profuse night sweats every night and my sleep otherwise became distorted. Also I'd noticed I became super sensitive to all dopaminergic compounds - even 100 mg of Phenylpiracetam would make me super wired and twitchy, not to mention any direct stims. So, daily vitamins stack needs adjusting. Psychedelic tolerance goes up high after few weeks - to trip normally I'd take up to 5-6 tabs, sometimes even would mix with Harmaline for stronger effects (please be super careful if you do so!).
After a while more I started noticing that I'd become more introspective and would have troubles keeping company of my regular buddies for long as I'd find them too shallow and that would be happening to all the people eventually so I decided to stop. Everything came back to normal baseline after about a month or two.
Now I like to supplement myself with a microdose once in a while but not on a regular basis - just when I could really use some inspiration!
Also, as an extra bonus, after so many experimentations with lysergamides I get immediate psychedelic response even if I touch dry papers and I can get objects in my vision field to melt pretty much at any time at all by will - it's all mind tricks! %)
Not sure if the same dosage technique could be used for ALD-52 but it seems to be indistinguishable from street LSD by many, so I'd give it a try with microdosing, but be careful if taking prescription meds or have any existing health condition.