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The Benzodiazepine Thread v. IV

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But, if you really feel the need, and think you can't get by, and it's for short term use, then maybe a benzo with less strength and abuse potential could help. Stuff like oxazepam, temaz and I'm very hesitant to say (due to past abuse) but good old fashion diazepam.
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Yeah, this pretty much sums it up nicely I think.

It's hypocritical for me to be preaching about using responsible benzo use, when I've got myself a habit again (this one the worst yet by far); but on the other hand, I'm in a good position to comment having been both a stupidly irresponsible user of benzos for recreational purposes, as well as having used them exactly as prescribed for short periods when it was needed.

Everyone's different, but I think diazepam is THE benzo for short term maintenance of general anxiety while other options (therapy, anti-depressants, herbal remedies, etc) are explored.

Diazepam works. Some need more than others, but it works. For acute panic attacks there's things like alprazolam, which again are invaluable in cases of severe (as in genuine) panic attack. This may not be a popular opinion, but I don't think that alprazolam should be scripted with repeats, or more than a few pills for emergency situations. It boggles the mind that a potent, short-acting benzo with extreme side effects and rebound anxiety after extended use would be prescribed on a regular basis.

Again, however, everyone's different and I don't want to offend people with that comment. I know for some people alpraz is the only thing that works for them, and it is a necessary thing.

I just find the idea of powerful, short-acting benzos on repeat script a recipe for making a bad situation worse.

Lastly, there is an RC benzo called Pyrazolam, and I'll be damned if it isn't the only benzo I've ever tried that does NOTHING WHATSOEVER other than kill anxiety. It really works. It is often sold in tablets which contain 500mcg which is kind of stupid because it's not that strong, but 1.5 or 3mg or pyraz has killed my anxiety so cleanly that I simply forgot it was there.

It's not recreational at all, IME. If you don't have anxiety, you won't feel a damn thing from it. It's not attractive because it only negates, it doesn't bring in relaxation and disinhibition. This is my experience. Maybe others have had different experiences.

But it begs the question: Why isn't that the first line of treatment for acute anxiety in the medical world? It doesn't impair motor coordination unless taken in VERY high doses, it has minimal effect on short term memory....

Anyone else had good/bad experiences with it?
 
^ Yes, I loved pyrazolam, it shown me how much anxiety I actually deal with daily. The relief from it pulled me out of depression some days too. Which to me seems like my depression is caused by my anxiety? (thought it was the other way around till recently).

I have a head pressure nearly daily, pyrazolam got rid of it completely. I've had similair results with other benzos, but this one specifically worked amazing.

I think this is because I'm more prone to head pressures when I'm tired, and pyraz didn't zonk me out like others I've used at a dose to kill that pressure.

So all benzos usually help my pressure, but if I've dosed too high and its got a lot of hypnotic properties it can become counter-productive towards what I'm trying to achieve (no head pressure).

Did that blabble make any sense?
 
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Halif said:
Lastly, there is an RC benzo called Pyrazolam, and I'll be damned if it isn't the only benzo I've ever tried that does NOTHING WHATSOEVER other than kill anxiety. It really works. It is often sold in tablets which contain 500mcg which is kind of stupid because it's not that strong, but 1.5 or 3mg or pyraz has killed my anxiety so cleanly that I simply forgot it was there.

It's not recreational at all, IME. If you don't have anxiety, you won't feel a damn thing from it. It's not attractive because it only negates, it doesn't bring in relaxation and disinhibition. This is my experience. Maybe others have had different experiences.

But it begs the question: Why isn't that the first line of treatment for acute anxiety in the medical world? It doesn't impair motor coordination unless taken in VERY high doses, it has minimal effect on short term memory....

Anyone else had good/bad experiences with it?
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What's the duration of Pyrazolam,,,in your experience..and yep the 0.5 tabs are stupid. Hopefully someone starts powder
 
Hey Worth buddy,

Sorry but it's really hard to say whgat the duration is like, because it's so 'monochrome' in effect that it flies under the radar - ad then over it again later.

What I mean to say is that Pyraz seems to do one thing only - remove anxiety. It really doesn't seem to do anything else. It does what it is supposed to do so well that it's actually hard to subjectively report on things like how long it took to kick in, how long it lasted, and what it felt like as it was wearing off. It's all relative to your level of innate anxiety. It's subtle but it works. Tings like that can be hard to

That's why I find Pyraz really interesting, it seems like such a functional and no-nonsense mmedication. I think it's great, personally.

When I start to have a real, growing sense of panic arise I take 4 of the yellow 0.5mg tablets, and thus far it has really stopped the anxiety from getting out of control. In other words, it stops a a panic attack if taken early on.
 
Of this guy started off on 6 mgs on Xanax a day he'd sleep 24 hourss. I have a guy 1mg and he slept 13 hours and I was the same was.
 
Its called Restoril and been in America for years. I never realized that was true until you said that.
 
AyahuascaSeeker13 said:
Prob been answered before, but a quick one.

Can one take 5mg of Valium safely at 12:30am after .5mg of xanax at 1pm?

Thanking the crew for ya help on this one!!
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Guessing its down the hatch already, but yes its very safe. Xanax has a half life of ~6 hours, so thats effectively gone now. These doses would be safe to mix even - not that you should.

Just remember valium has a half life of 100+ hours, so be careful in the days after taking it. I forget a lot of the time, 1 drink feels like 3 the day after then you remember why pretty quickly.
 
Halif said:
Hey Worth buddy,

Sorry but it's really hard to say whgat the duration is like, because it's so 'monochrome' in effect that it flies under the radar - ad then over it again later.

What I mean to say is that Pyraz seems to do one thing only - remove anxiety. It really doesn't seem to do anything else. It does what it is supposed to do so well that it's actually hard to subjectively report on things like how long it took to kick in, how long it lasted, and what it felt like as it was wearing off. It's all relative to your level of innate anxiety. It's subtle but it works. Tings like that can be hard to

That's why I find Pyraz really interesting, it seems like such a functional and no-nonsense mmedication. I think it's great, personally.

When I start to have a real, growing sense of panic arise I take 4 of the yellow 0.5mg tablets, and thus far it has really stopped the anxiety from getting out of control. In other words, it stops a a panic attack if taken early on.
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Yeah sounds like a waste unless they pop up with 1mg,2mg or powder
 
Captain Brewster;11866206 But said:
and[/B] it's for short term use, then maybe a benzo with less strength and abuse potential could help. Stuff like oxazepam, temaz and I'm very hesitant to say (due to past abuse) but good old fashion diazepam.

RLS is a bitch, I hate it.... Sometimes when it's really bad, and I'm getting frustrated from it, I leave the bedroom, to the lounge then 25 squats (now dont go thinking I'm much of a fitness freak person, actually far from it, do enough physical shit at work these days). That usually keeps them at bay for a little while. If it's real bad and it comes back, repeat.
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thanks for the concern man but yeah I only want clonaz for those times the RLS is too far for me to control mentally and in my head Xanax will always be the devil to me now. Reasing I say clonaz apart from other benzos is sadly Ive abused quite a few and when I did my Xanax binge I was taking 60mg a day (no that's not a typo) on average of Xanax and have developed a ridiculous tolerance to benzos, should be technically dead but its amazing how the body can repair itself if you take care of it!
 
Yep, the body is amazing in its ability to repair and recover. The mind/psyche, however, is the real danger with benzo abuse. The side effects from long-term benzo abuse, or even short term heavy abuse, can really knock you around. It's amazing how long the psychological effects can hang around long after any physical withdrawal aspects have left.

It can make you think you've gone mad or damaged your brain forever. Very scary.
 
rm2x said:
Been using etizolam blotters dosed at 2mg for a while now. Really handy to carry around and effective....
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In fact recently I have been researching extensively the pharmacological and biochemical pathways by which Etizolam works (the basic ADME and pharmacodynamics), with a focus on it's down-regulation of membranous integral protieins/receptions and the mechanism (and possible ways to prevent/slow down) the endocytosis and ultimately phagocytosis of the said receptor (read: tachyphylaxis).

Thienotriazolodiazepines - as a benzodiazepine class - are interesting in themselves but the Etizolam's pharmacological profile, specifically regarding the GABAA subtypes by which it is able to produce it's MOA seemingly produce results (again re: receptor down-regulation) not seen in many (any?) similarly structured benzodiazepines (imo). In fact tachyphylaxis is substantially reduced (and additionally withdrawal symptoms) when dosing Etizolam for a substantial period.

Imo it's too difficult to elaborate much further on this forum as to why, however if you're interested (warning though, it does get a bit technical mid-way through): Low tolerance and dependence liabilities of etizolam- Molecular, functional, and pharmacological correlates.



Edit: That's not to down-play the effects of chronic benzo use and the devastation (personally seen first- and second-hand!) it can cause.
 
Cheers^^ I only use them occasionally, more akin to a social drink. If we go to a more pub I have a few blotters or tabs and a mineral water as I dont really drink.
 
I think xanax has a 12 hour half life before it's fully metabolized and eliminated from the body but the doses you mention are standard prescribed doses. No need to worry unless the pharmaceuticals in question are not prescribed together ie xanax for anxiety and diaz for sleep disorder. But yeah 12 hours is plenty... Not like phenazepam...
 
advise on dosage for liquid valium

I'm interested to know if should take the same about of liquid valium for recreational purposes, as I take in pill form. Generally I'll do 20 Mg at a time and maybe 20 more depending on many stimulants I'm mixing them with. Would it be any different for taking liquid in form?
 
It would be the same as its being consumed orally. Assuming you know the exact potency of your liquid valium that is.
 
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