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  • BDD Moderators: Keif’ Richards | negrogesic

The BDD Social/Information Booth V19 - The After Party

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Fucking aye! We got The Rock Monster in the crib!

The OCD guys coming outta the woodworks!

Hi guys so currently my only access to the internet is today and thursday while I sort out problems. While I'm at this job... I think I might even work friday also. Ringing up about a house to move into after work and things might be sorted quick.
 
I've been thinking about suggesting BuTrans to my docs...any information I should know before suggesting the patch and what does it mean as a benzo/opioid chipper? I've just heard things like nothing can get through that blockade. Would fentanyl be the only thing that might help breakthrough if I needed breakthrough meds?
 
Any recomme.a

Was wonderin what the potential for feelin good was on these drugs and what exceeds safety?

1. Diazepam 5 mg (with Xanax I was up to 14 mg)
2. Flexiril 5 mg (most I took was 20 mg)
3. Vistaril 25 mg (have taken 100-150 mg)
4. Ambien 10 mg (have taken 40 mg at once)

I have a call into my psych to at least switch me back to Xanax bc let's face it, Valium is a weak joke!

Thanks for all your help! I ran outta oxy and hydro and lookin for some not tell really get me high but just to feel hapoy again and relaxed.
 
So I would still be able to take other opioids and them work? I just know that once that bupe latches on to a receptor, there's not much that can get through it. And looking on wiki (which I know isn't the best source but.....) transdermal was about 50% BA...only thing higher mentioned was snortin the shit, which was about the same. Would the bupe patch seem ideal? And sorry if this isn't "social material." Should I go resurrect an old bupe thread or what? (Honest Question)
 
This really is not allowed. But I will say that if you were up to 14 mg Xanax daily, 5 mg Valium ain't gonna do shit. 1 mg Xanax = 20 mg Valium, that is sort of what I have generally believed and gone by, but the conversion charts vary quite a bit. I wouldn't think you would need 280 mg Valium to feel good, that seems rather high even if that would be equal to 14 mg Xanax. While benzos are cross-tolerant, I would go with a lower dose of Valium if I were you, def. not 280 mg. AND, Valium and Xanax hit you differently, have different effects, and differnt durations of action, as well as half-lives. The Flexiril won't do much. Vistaril is an anti-histamine, if you had opiates they might be worth your while, but I've never been into mixing anti-histamines and opiates. Ambien is a z-drug, very benzo like, effects everyone differently, so you know how it effects you. You really know yourself best, so just ask yourself what you feel is best. I can't answer that, not just because of the rules, but because I don't know.
 
Anyone ever potentiated clonazepam with omeprazole (Prilosec)? How long after you take the omeprazole do you take the clonazepam?
 
Sorry I didn't mean a low BA, just not a very efficient ROA IMO. I mean like it's an incredibly low dose. That is why I presume you'd be able to break through.

I would prefer if you started your own question Doug
 
I've used cimetidine (Tagamet) and i remember reading about omeprazole. Can't remember much of what was said about it. I think it was less of an inhibitor than cimetidine but maybe i'm mixing that up.
here's some better info:

Effect of omeprazole and cimetidine on plasma diazepam levels.
Andersson T, Andrén K, Cederberg C, Edvardsson G, Heggelund A, Lundborg P.

The effects of steady state dosing with omeprazole and cimetidine on plasma diazepam levels have been studied in 12 healthy males. Single doses of diazepam (0.1 mg.kg-1 i.v.) were administered after one week of treatment with omeprazole 20 mg once daily, cimetidine 400 mg b.d. or placebo, and the treatment was continued for a further 5 days. Blood was collected for 120 h after the dose of diazepam for the measurement of diazepam and its major metabolite desmethyl diazepam. The mean clearance of diazepam was decreased by 27% and 38% and its half-life was increased by 36% and 39% after omeprazole and cimetidine, respectively. Neither drug had any apparent effect on the volume of distribution of diazepam. Desmethyldiazepam appeared more slowly after both omeprazole and cimetidine. It is concluded that the decrease in diazepam clearance was associated with inhibition of hepatic metabolism both by omeprazole and cimetidine. However, since diazepam has a wide therapeutic range, it is unlikely that concomitant treatment with therapeutically recommended doses of either omeprazole or cimetidine will result in a clinically significant interaction with diazepam.

Read more: http://www.drugs-forum.com/forum/showthread.php?t=90243#ixzz1le3U90i1
Click to expand...
 
so it looks like cimetidine is mildly better - but then again different people say cimetidine does or doesn't affect Clonazepam. I've read people argue for and against here on bluelight. Personally I think it works; I would do ~400-600mg cimetidine about 30mins before taking my benzos before bedtime; one of which was temazepam which is a member of the 3-hydroxy family of benzos which are NOT affected by cyp3a4 inhibitors, if my knowledge serves correctly.

Naon - Omeprazole is certainly a PPI but I believe its action on benzo activity is simply due to its enzyme inhibition. Could be wrong there but I think Omeprazole just happens to be a PPI that also inhibits cyp3a4
 
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Wow.

I'm currently looking at all the forms doctors need to fill out to prescribe certain medications....

Interesting.
 
well while your at it trips .... i think i need to re-up my Rx's for- ketamine, oxy, klonopin, diazepam, dexedrine, mmj, temazepam, and just about anything else that looks interesting from schedule 2 or higher...

so go ahead and send those along then, quick snap
 
first off we don't do "What should I take" threads in BDD:

Here's the BDD guidlines- BDD-Guidelines

your benzo tolerance is going to rule out the diazepam and ambien unless you get huge amounts of them...

the toher two both have histamine activity which could get unpleasant unless you're into the dysphoria from high dose anti-histamines... i know very little about them so perhaps their H1 activity doesn't dominate.
 
^This.

In the interest of harm reduction however...combining two antihistamines isn't a good idea. Pick one or the other and find out which one works best for you.

I'm going to move this into the BDD social thread, where discussion of combinations is part of what we do...
 
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