Hi,
I just wondered if this compound, the most potent anabolic steroid (AFAIK) is available. I know that RU-2309 was developed and used by the Turkish Olympic weightlifting team (who all got banned) and that is just a slight modification to THG. It would be synthetically complex to make but they wanted as close to THG as possible it seems. BALCO was not exactly a group of able chemists - THG is a 1-step synthesis although it is now a controlled drug. Of course, the hemi-acetal derivative IS legal so I'm wondering if that is turning up.
THG = (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
THG (methyl) Hemiacetal = (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopentaphenanthren-2-ol
The ethyl hemiacetal avoids the tiny traces of methanol formed by hydrolysis to active (but truly TING amounts) and the acetal can be with any alcohol(s) or cyclic using ethylene glycol or propylene glycol or indeed any diol that doesn't cause too much ring-strain or alters kinetic by lower solubility. Ketone<->enol tautomerism offers unsaturated esters, another gamut of options.
In short, there is a panopticon of possible legal analogues is well understood but it doesn't look like technical knowhow or indeed interest is involved with the production of novel steroids. They are of course not without their own risks and I only highlight this on the basis that people misusing steroids meant for animals (!!!) and at least this offers a known compound. The reason I specifically mentioned the methyl hemiacetal is that it is possible to go from gestinone --> THG methyl hemiacetal without raw THG turning up in the solution thus nobody is in breach of UK law (AFAIK) apart from unlicensed pharmaceutical so strictly, this is a reference ligand because forming the methyl hemiacetal of an unknown can use a THG-hemiacetal as a reference compound i.e. it is of value in detecting the illegal use for PED.
I wish to make it clear that while 1-step may seem 'do-able', it does use a pyrophoric reagent and a flammable solvent. Get it wrong and it could cost you your home, your family and/or your life. I am not an expert on steroids but I do believe that informed consent is only possible if the compound is correctly identified. AFAIK THG was given sublingually dissolved in a solvent. I don't know how stable the (hemi)acetals & unsaturated esters are. The former is NOT technically an ester so MoDA doesn't cover it and since the unsaturated esters dehydrate the molecule (loses a H2O) the law would see it as an ester of a non-controlled item.
Don't break the law. Don't do stupid things. Don't harm anyone.
I just wondered if this compound, the most potent anabolic steroid (AFAIK) is available. I know that RU-2309 was developed and used by the Turkish Olympic weightlifting team (who all got banned) and that is just a slight modification to THG. It would be synthetically complex to make but they wanted as close to THG as possible it seems. BALCO was not exactly a group of able chemists - THG is a 1-step synthesis although it is now a controlled drug. Of course, the hemi-acetal derivative IS legal so I'm wondering if that is turning up.
THG = (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
THG (methyl) Hemiacetal = (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopentaphenanthren-2-ol
The ethyl hemiacetal avoids the tiny traces of methanol formed by hydrolysis to active (but truly TING amounts) and the acetal can be with any alcohol(s) or cyclic using ethylene glycol or propylene glycol or indeed any diol that doesn't cause too much ring-strain or alters kinetic by lower solubility. Ketone<->enol tautomerism offers unsaturated esters, another gamut of options.
In short, there is a panopticon of possible legal analogues is well understood but it doesn't look like technical knowhow or indeed interest is involved with the production of novel steroids. They are of course not without their own risks and I only highlight this on the basis that people misusing steroids meant for animals (!!!) and at least this offers a known compound. The reason I specifically mentioned the methyl hemiacetal is that it is possible to go from gestinone --> THG methyl hemiacetal without raw THG turning up in the solution thus nobody is in breach of UK law (AFAIK) apart from unlicensed pharmaceutical so strictly, this is a reference ligand because forming the methyl hemiacetal of an unknown can use a THG-hemiacetal as a reference compound i.e. it is of value in detecting the illegal use for PED.
I wish to make it clear that while 1-step may seem 'do-able', it does use a pyrophoric reagent and a flammable solvent. Get it wrong and it could cost you your home, your family and/or your life. I am not an expert on steroids but I do believe that informed consent is only possible if the compound is correctly identified. AFAIK THG was given sublingually dissolved in a solvent. I don't know how stable the (hemi)acetals & unsaturated esters are. The former is NOT technically an ester so MoDA doesn't cover it and since the unsaturated esters dehydrate the molecule (loses a H2O) the law would see it as an ester of a non-controlled item.
Don't break the law. Don't do stupid things. Don't harm anyone.
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