My only comment is to welcome you here and to say you obviously don’t sound like Carl

(his posts at times frustratingly and cryptically short n sweet.)
I wish I could hang in this conversation but I can’t.
-GC
Phew what a relief, that means I'm inkognito

Cryptical!

I mean, not that I care, as I am obviously not that person.
But that guy sounds like an asshat with protruding ears, and..., and screw this guy too, yeah!
I wholeheartedly agree
I've not yet found out who you are though
Welcome and thanks for this contribution! That's cool that you made and tested something new.
I am really interested in aminorex analogues. I have never had a chance to try 4-MAR, but it has always sounded like a pretty ideal stimulant to me. Until recently though, no analogues had hit the commercial scene. However, lately there have been 4-4-DMAR (some reports of cardiotoxicity potential, and some negative reviews but also some strong positive reviews), as well as 4,4-FMAR, as well as the Cl and Br versions of that. The halogenated ones sound decent, I wanted to give them a try myself but minimum order quantity is 5g unless you want to spend WAY too much for 1g and... yeah, I don't need 5 grams. I contacted the place to ask if I could do 5 grams mix and match of all 3, but they were unwilling to do that.
In any case I hope more aminorex analogues are explored and made available. I am particularly interested to see what would happen when the 2,5-dimethoxy-4-X substitution pattern is explored, that for amphetamines results in wonderful full spectrum psychedelics that are among the finest substances in all the land. Of course the same might not hold true for aminorex analogues, but I'm really curious to know.
Thank you!(both)
Well, the thing with 4-MAR is, that it actually is not that great.
Since it happens to come, or is said to come in, a nice crystalline shape, and since it is also said to act like meth(it really, really does not), it often happens that some tweakers get sold, for the first time ever, some nicely shaped crystals.
And of course it is better than what they usually take.
Because of that, they come to the conclusion it must be 4-MAR.
There are quite a few reports on erowid which start something like that.
I found it disappointing, overly long acting, boring(yes) and it lacks the euphoria it is named after.
I also think, that the likelyhood of it developing pulmonary hypertonia is greater than it is for plain aminorex.
It really is not that great, there is some sort of mysterical aura around it, like it surrounds few drugs, and mostly those who are not accessible.
Other examples would be mephedrone, but only after it got banned, and phenmetrazine, which now have similar mysteriously good effects attached to them.
I mean, sure, phenmetrazine is great, but nobody mentions the high dosage required, because nobody has any real world experience with it.
Not talking about mephedrone at all, thats really bad.
If I want to be really down and depressed the next day, without getting much in return, I would do something else thats stupid but doesn't cost lots of money(sorry no good comparison for that, nobody wants that).
So in short, the aminorex analogues are much more interesting.
They don't act longer than a half day until you can sleep, and especially aminorex itself is quite euphoric and abuseable.
If you're not a fat old lady, it is also not really dangerous, but people tend to forget to which audience it got prescribed to for the most par.
There is also another thing involved, which has to do with its strange aphrodisiac action in especially postmenopausal women.... I don't know much about it though, but its fascinating.
It also has the ability to restore the libido, not just in postmenopausal women, but also men who got limp-dickedness due to old age or what, as I got told.
Can't confirm this either.
Although its not shrinking as amphetamine(s) tends to, or not that much.
However, its relation between effective and deadly dose is not that large as it is with other drugs, there is a paper
out describing 30 overdoses, all between 1-2mg/kg, even up to a small child(or several, no idea, its just mentioned that it doesn't causes lasting damage in those people, nobody died either, however, that was with pills and not the pure substance).
It should be treated with much consideration, as it actually was the cause of quite a few deaths, but properly dosed its not bad at all.
haribo1 surely could confirm this all.-
So, in case there are any research drugs around, they will definitely kill people, if they are 4-MAR analogues.
They are less likely to kill (as much) people as aminorex analogues.
Both is true.
If I would own a conscience, I wouldn't sell those.
But then again, nothing else either, because I'm in the possession of said conscience.
Guess other people come to different conclusions and thats why they hit the streets.
However, what interests me are the aminorex analogues only.
I've seen the forensic paper about 3,4-MD-4-MAR or MDMAR as they call it, and all the follow ups of that too, including the receptor affinity assay.
That was quite interesting, but as said, I suspect the 4-methyl group to be much more dangerous than most people think.
After all, aminorex caused pulmonary hypertony in fat old women.
But 4-MAR did the same in that small uncle, aunt, nephew family in, where was it, ohio?
It of course has a genetical predisposition, but you just don't randomly develope this in your early twentys even if you do coke, meth(or aminorex) like there's no tomorrow.
But 4-MAR caused this.
And also, it was discovered a bit, I think three years, earlier than Poos et al wrote his papers about these.
Why have they not marketed this analogue, but brought aminorex on the market instead?
To me its apparent, that they knew about some of these things.
Lets not forget that thalidomide(great sleeping pill) was still brought on the market after one of its inventors brought some home for his pregnant wife, and his xhild got born without ears.
That girl was in school before the medication was finally pulled off the market.
They knew there was something very badly wrong, but did not care.
Why should it be different with aminorex?
They likely knew it was less harmless than 4-MAR, but they likely also knew, that neither of them or any of the other analogues was completely harmless at all for the targetted part of the population.
Well anyways, it is a nice and underestimated drug, and everyone thinks 4-MAR which I can only sarcastically call "euphoria", is as good as some reports make it out to be.
Its interesting for sure, and definitely has the one or other use, but it is not that.
It will be a disappointment if thats whats expected.
For this reason, I actually do not hope any of these things appear on the market anymore.
Its like a trap full of honey, people will try them, be disappointed, take some more and more, and five days later their parents bury them.
And in turn, bad press for these drugs.
But I would definitely also like to try some of the other two carbon analogues instead.
Not the 2,5-diMeO though, but I think, after these "MDMAR" papers got published, that the analogue without the 4-methyl could be of interest.
I just happened to have the naphthyl precursor, and in turn found the idea so interesting, and the smell of the precursor also very nice, I had to follow it all the way to the end.
Although if people just would know how accessible these things are.... they would be astonished.