I and others have experienced worse withdrawal from Buprenorphine than from Heroin or Methadone. Erowid used to have several such reports in the train wrecks section of the Bupe experience vault, they are no longer there as far as I know. Once dependant on Bupe after starting a maintanence regimine, so it goes, tapering down is very easy, easier on Bupe than any other Opioid. But going from any dose of Bupe, taken daily or every other day, is impossible. The withdrawal symptoms encompass the full range of Heroin acute withdrawals symptoms, felt in a similar intensity. The big difference though is the psychological aspect. Any opioid withdrawal produces severe despair, depression, anxiety, insomnia, etc. From Bupe withdrawals, these symptoms were much more severe than from Heroin or Methadone. A mix between mania, paranoia, panic and suicidal despair on top of the physical withdrawal symptoms. Needless to say I and every other case of someone similar to mine went back on either Bupe, H or Methadone.
Could these more severe psychological withdrawal symptoms be linked to Buprenorphine's anti-depressant activity that is so often touted? Stopping SSRI/SNRI/MAOI/etc anti-depressants results in a horrible withdrawal syndrome, which horribly intense psychological symptoms. I believe this is the cause, once the anti-depressant function of Bupe is better understood so to will its role in the withdrawal syndrome.
Has anyone else experienced similar morbid withdrawals from Bupe?
Is that a plausible explanation?