leungkachong
Bluelighter
I believe this thread is more suited for here than the health forum as I am interested in mechanism more than anything, the following is simply context.
Over the last bit, a 17 year old male suffered from what was most likely a transient ischemic attack (TIA). He has had what was beleived previously to be heart problems, yet no direct causation could be found. Ectopic atrial tachycardia had been recorded during previous episodes, however getting to an ECG in the middle of an attack was always of course an issue. No direct cause could be found by the top cardiologists in Canada.
The most recent (and most severe) attack occured whilst on LSD. As for context, this occured after a couple day period of sleep deprivation, being placed in a unaccustomed hot environment, with little food for around 2 days, and most likely dehydration (very low water replacement, and alcohol consumption).
Public information on strokes/TIAs list LSD as a risk factor, along with strong CNS stimulants. However no direct information concerning LSD and TIAs could be located. Although I am aware of the complicated and multi-causative nature of what is described, any input into the risk associated and the role played by LSD in this would be very helpful!
Over the last bit, a 17 year old male suffered from what was most likely a transient ischemic attack (TIA). He has had what was beleived previously to be heart problems, yet no direct causation could be found. Ectopic atrial tachycardia had been recorded during previous episodes, however getting to an ECG in the middle of an attack was always of course an issue. No direct cause could be found by the top cardiologists in Canada.
The most recent (and most severe) attack occured whilst on LSD. As for context, this occured after a couple day period of sleep deprivation, being placed in a unaccustomed hot environment, with little food for around 2 days, and most likely dehydration (very low water replacement, and alcohol consumption).
Public information on strokes/TIAs list LSD as a risk factor, along with strong CNS stimulants. However no direct information concerning LSD and TIAs could be located. Although I am aware of the complicated and multi-causative nature of what is described, any input into the risk associated and the role played by LSD in this would be very helpful!
. Hmm.... Even if all TIAs aren't thrombotic, that seems a reasonable assumption in this case. Searching for information relating to this case previously, I'd searched mainly for information regarding the "serotonin-mediated heart" (as the heart was considered primary cause, rather than secondary effect previously). I know that the effect is receptor dependant, and 5-HT2 is vasoconstrictive, and has (short-term?) positive feedback loops, releasing more and amplifying the action of other vasoconstrictors in the area (angiotensin, norep). This review was pretty helpful: