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How combat sports are researching microdosing psychedelics to treat brain injuries

by Peter Kahn

When it comes to combat sports, one thing is certain. Fighters are taking a risk every time they compete. Whether it’s a boxing ring or the UFC Octagon, fighters know they’re going to get hit in the head. Whether it’s a punch, a kick, a knee, or elbow, the brain is going to suffer trauma. It’s inescapable. While research has made strides over time in helping understand how and why trauma is caused and the long term effects of this trauma, new research is being done as to how to potentially treat these injuries in combat sports competitors.

There have been recent reports regarding the UFC looking into research surrounding micro-dosing psychedelics. The UFC has had a dialogue with Johns Hopkins University about its psychedelics research to see if the drugs can be an asset for fighters that are combating brain issues. The UFC has been a prominent financial supporter of a professional athlete brain study being conducted at the Cleveland Clinic Lou Ruvo Center for Brain Health, contributing another $1 million recently.

UFC president Dana White recently told Yahoo Sports,“They’re micro-dosing psychedelics and they’re saying that it’s helping some of these guys with brain injuries,” White said. “We’ve talked to Johns Hopkins and we’re working on getting us involved with that too. ... The list goes on and on of all the things that we’ve done to try to improve the sport.”

Another company that has taken a strong interest in this category is Revive Therapeutics. The Toronto based company is a life sciences company focused on the research and development of therapeutics for infectious diseases and rare disorders, and it is prioritizing drug development efforts to take advantage of several regulatory incentives awarded by the FDA such as Orphan Drug, Fast Track, Breakthrough Therapy and Rare Pediatric Disease designations. Currently, the Company is exploring the use of Bucillamine for the potential treatment of infectious diseases, with an initial focus on severe influenza and COVID-19. With its recent acquisition of Psilocin Pharma Corp., Revive is advancing the development of Psilocybin-based therapeutics in various diseases and disorders. Revive’s cannabinoid pharmaceutical portfolio focuses on rare inflammatory diseases and the company was granted FDA orphan drug status designation for the use of Cannabidiol to treat auto immune hepatitis and reperfusion injury from organ transplantation.

What does all of this mean? It means more and more companies like Revive are understanding there’s a need to help these fighters that are dealing with brain issues long after they’re done fighting.

“We are excited the UFC is showing interest in Psilocybin for the treatment of brain injury. Our recently signed letter of intent with PharmaTher to acquire their psilocybin program which includes significant research in neurological brain injury will be addressing these key disorders. In the future psychedelics will play a significant role to treat a number of conditions and Revive’s tannin chitosan composite psylocibin formulations will continue down this clinical path in supporting these initiatives,” said Michael Frank, CEO of Revive.

Revive will also be working on a biosynthetic version of psilocybin to be based on a natural biosynthetic enzymatic platform, which was developed by Dr Gavin Williams, a professor at researcher at North Carolina State University. The platform is said to have the potential of providing a simple and efficient method for rapidly producing natural products, such as psilocybin.

The tech reportedly works via the use of an engineered enzyme pathway in E. coli. The science is based on the development of an artificial enzymatic platform that has been named the “Alcohol Dependent Hemiterpene,” with the pathway reportedly used as a key building block for psilocybin and its derivatives.

Revive has identified that it intends to develop and commercialize its own pharma-grade psilocybin with this biosynthesis technology in the future, which will be used to support its current psilocybin-based product pipeline.

Frank said, “We are excited to partner with NC State and work with Dr. Williams and his team to develop a proprietary form of psilocybin that can be produced at scale for research and commercial purposes while allowing us to create our own unique product offerings with psilocybin in different delivery methods so as to treat the various mental health conditions and other diseases that psilocybin has shown to be a potential viable treatment option for.”

While it’s too early to understand what this will mean to current fighters and how a safe and controlled micro-dosing regimen can be implemented, a path is being created to find a new way to help these athletes with life after competing.​
 
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Why do road warriors & athletes who sustain sports injuries all benefit from CBD?

by Dr. Leah Zachar | CBD Testers

Daily, athletes push their bodies to the limits, and very often they face muscle stiffness. Many of these muscle pains turn into injuries and often cause chronic pains which interfere with further sports participation – and may cost them their job.

For the past few years, professional athletes, such as Nick Diaz have started using CBD. Why? Because CBD is a better alternative to all the painkillers and drugs they are already prescribed to reduce their pain.

The human body contains an endocannabinoid system which includes CBD. Unlike THC (marijuana), CBD does not get you high. However, CBD offers you all the medical benefits of THC – and a few more that THC does not offer – such as treatment for osteoporosis and improved fracture healing rates.

Our body produces CBD naturally. However, in times of stress – physical or mental, our body may not be able to produce enough. CBD given by tincture, or softgels replaces the CBD deficiency and helps the body to recover from the sports injury quickly.

What can CBD do for the athlete? CBD is effective for treating pain, muscle spasms, muscle sprains, soft tissue injury, and it can also help to heal broken bones.

Additionally, using CBD for pain relief does not have any of the side effects that experienced by opioids, analgesics, and muscle relaxants. An added comfort is that CBD is NOT picked up on any drug tests, as opposed to THC – which is picked up on all drug tests.

Question: I have a medial meniscal tear. The orthopedic surgeon said it is not severe enough to operate. Well – it is certainly severe enough to interfere with my tennis. Can you help?

In medial meniscal tears, you have swelling, pain, and sometimes heat at the injury site. CBD takes care of all three. CBD works at the TRPV-1 receptors and blocks them. This is the mechanism by which the CBD helps to heal the meniscal tear and allows you to go on with the game.

Question: I live for playing Rugby. I played it before I got married, while on our honeymoon, and every chance since for the last 14 years. Now, at age 37, my knees are killing me. My orthopedist is telling me that I have early osteoarthritis. He recommends I stop playing. That’s not going to happen. Rugby is my first wife. Karen, the woman at home, is my second wife.

You certainly do not have to give up your first wife – Rugby. As for Karen, I’m not a marriage counselor; I’m a M.D. – CBD specialist. There are endocannabinoids present in the synovium of the joints of people with osteoarthritis. This is the location of the pain, warmth, and inflammation seen in osteoarthritis.

In the joint is the amino acid – FAAH. CBD blocks this and the result is reduction of swelling & pain. In addition, CBD blocks the TRPV1 receptor and result again, is reduction of swelling & pain. So, there are two mechanisms by which CBD can improve your symptoms and allow you to continue to play. Continue to see your orthopedist – an invite him to join our Ask A Doctor Facebook forum.

 
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An ex-Blackhawks player's quest to treat brain injuries with psychedelics

Led by Daniel Carcillo, Wesana raised $4 million to use 'magic mushrooms' to treat traumatic brain injuries.

by Jim Dallke

Daniel Carcillo retired from the NHL in 2015, not long after he sustained his seventh concussion. As a member of two Stanley Cup-winning Chicago Blackhawks teams in 2013 and 2015, Carcillo was an enforcer, regularly doling out hits and checking the opposition into the boards.

After nine seasons in the NHL, his hockey career had not only taken a toll on his body, but also on his brain. A career's worth of hits to the head resulted in headaches, insomnia, slurred speech and memory loss. He had a hard time looking at his phone. He wanted little to do with his newborn son.

Carcillo said he spent hundreds of thousands of dollars to treat his traumatic brain injuries (TBI), working with top CTE pathologists and concussion clinics on a range of different protocols and treatments. Nothing worked.

"I thought I was hopeless because I tried everything," he said in an interview. "I read every paper. And I couldn’t help myself. That's when suicidal ideation crept in for the first time in my life. It got really scary."

Luckily, Carcillo said, a former teammate introduced him to a farm that grew psychedelic mushrooms. He took a dose of psilocybin, the naturally occurring substance found in "magic" mushrooms that provides a psychedelic effect, and woke up the next day feeling better than he had in years.

"I felt a little bit of joy come back in my life," he said. "I wanted to grab my phone and call my wife right away and reconnect with my kids. I felt like the brain fog and fatigue was starting to lift. It just got better progressively as the days went on."

Carcillo began treating his brain injuries with a regular low dose of psilocybin for six months, and said his brain tests were coming back cleaner than they had in years.

From there, he knew he wanted to bring this same level of treatment to other survivors of TBI who might also benefit from psilocybin. So in 2020 he founded Wesana, a life sciences startup that aims to use psychedelics to treat TBI. In January, the company raised $4 million in funding from The Conscious Fund and Ambria Capital to begin preclinical trials this year, with hopes of starting human clinical trials in 2022. Wesana is awaiting approvals from the FDA and Health Canada.

"The company's first drug pipeline will look to focus on TBI-related depression," Carcillo said.

The startup aims to develop formulations and protocols to help those with brain injuries, but Carcillo is quick to note that psilocybin alone isn't enough to fully treat TBI. He expects the drug to be used in combination with other proven therapies.

Ultimately, Carcillo said he hopes Wesana can treat athletes, veterans, domestic violence victims and others who are struggling with TBI.

"I was there. I don’t want anyone else to live in that space," he said. "I feel really confident that the way this has worked in me, it will work in others."

Carcillo is building Wesana alongside co-founder Chad Bronstein, who's also the co-founder of Fyllo, a marketing and compliance startup in the cannabis industry. Other Wesana leaders include COO Dawn McCollough, the former head of medical research operations at Biogen; Director of Athlete Relations Ian McCall, a former MMA fighter; board member Mitch Kahn, the founder of Grassroots Cannabis; and chief strategy officer Mark Wingertzahn, who led clinical development teams at both GSK and Pfizer.

A handful of companies and universities are researching the therapeutic potential of psychedelic drugs such as psilocybin. In 2019 John's Hopkins opened the Center for Psychedelic and Consciousness Research, where it's studying the effectiveness of psilocybin as a therapy for opioid addiction, Alzheimer's disease, PTSD and other disorders.

Ultimately, Carcillo hopes he can bring the health benefits of psilocybin to more patients and usher in a new era of TBI treatments.

"It's imperative that we get this medicine to the right people," he said.

 
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Improving mental performance with LSD*

by Reilly Capps | The Rooster | 5 Dec 2016

Most everyone likes a little jump every now and again to help them through the day: coffee, nicotine or ADHD meds are popular. But some real go-getters are taking that up a notch. Business people, students and professors alike are all taking small doses of LSD, psilocybin or mescaline and then going to work or school per usual. Most say they do great.

"Anna" is a CU Boulder graduate and professional in her late 30s. She takes about 10 mcg of LSD — about 1/12th of a dose — most Mondays and Thursdays. She’s made exceptional strides in her life since beginning to microdose.

“I've been microdosing for about a year, and it's been one of the most productive, happiest years of my life,” she continues. “I went back to night school, got two new jobs, got engaged. I've changed a lot of things lately. Exercise, meditation, eating better. I love work more than ever, especially on acid. I love my partner more than ever, especially on acid. And I love acid. I still drink coffee, though. I just take LSD with it.”

The man who discovered LSD, Albert Hoffman, was an amazing chemist — but not a great businessman. He told people what would happen to them on large doses (a few hippies ended up in mental hospitals). Though Hoffman himself sometimes took LSD in small doses to help with his thinking.

"If Sandoz (Hoffman's company) had paid attention to what happens on small doses, there never would have been a market for Ritalin," says James Fadiman, one of the world's foremost psychedelic researchers.

Fadiman should know. He ran an experiment in the 1960s where engineers and designers took moderate doses of mescaline (100 mcg) to work on intractable problems in their field. The results were nothing short of incredible. They said they were able to think about the problems at a basic level, be more open to novel solutions, feel heightened motivation and be less judgmental of their own bad ideas.

They walked away with new designs for mechanical devices, space probes and even business letterheads (and probably also a deeper appreciation for Pink Floyd). Prudently, given all these successes and happy people and no apparent downside, the government halted the research in 1966.

Despite all that success, Fadiman says it never occurred to him to try small doses.

"We missed it entirely," Fadiman says.

Nevertheless, over the past 5 years, Fadiman's friends have been whispering to him that small doses of LSD, psilocybin, mescaline, 2C-E and other psychedelics have helped them be better workers and citizens — without tripping their faces completely off. Fadiman has collected about 200 microdosing case reports, from all kinds of people, from college students to a guy who runs a $200 million medical devices company.

A small percentage of the reports are negative, he says; microdosing can worsen anxiety and the manic phases of bipolar. It also reacts badly with lithium, among other things. But the vast majority of reports, he admits, are positive.

Some people think LSD microdosing is the future of psychedelic drugs. Entrepreneur Paul Austin, for one, is so convinced by his 7 months of microdosing LSD once or twice a week that he started a website about it. He’s also collected about 100 case reports and claims 95 percent are positive. Google searches for microdosing, he says, have increased exponentially over the last year. "I don't think it's a panacea," Austin adds, "but I think psychedelics will be one more tool people can have." He's even organized an event in the Netherlands Dec. 17 where people can try out microdosing with psilocybin truffles, which are tolerated there.

So while the government may always claim that LSD and magic mushrooms are as dangerous as heroin and more dangerous than cocaine, and some doctors will still say that acid makes you legally insane, Fadiman says that's not true: "Used correctly,” Fadiman adds, microdosing “LSD seems to move people toward better mental health — used correctly is the magic word there."

Although, it turns out, people have different definitions of "correctly."

"A.L." is a college professor who used LSD to help him get his PhD.

He says:​
My definition of microdosing is probably different from a lot of people: one half to one hit, taken every 8 hours for up to 72 hours straight. You're still productive, you still do shit, you just feel really cool all the time. You can go to class and when they ask you about shit, you'll be able to respond, you won't sound like a nipplehead. I'm not saying people should go do this. I'm not a doctor.

A.L. is obviously an unusual case. The key to microdosing, says Fadiman and most other microdosers, is to take a "sub-perceptual" dose, meaning: you can't quite tell you're on it. You just feel happier, more interested in your usual work, more interested in your co-workers.

LSD also seems to be a replacement drug for a lot of college students. "Matt," a student, father and husband at CU Boulder in his 20s says:​
For about a month, I stopped taking my ADHD medication and started microdosing LSD. It helped me think differently. Everything was coated in a thin layer of significance. Then I went back to my ADHD meds. I compared my scores on my tests between the two months. They were about the same. But, honestly, I liked the LSD better. It didn't have as many nasty side effects.

Because it's not easy to legally research and obtain this stuff, there is little conclusive data on how many people microdose, what LSD does to people long-term or whether microdosing tends to help people reach their dreams. It’s all anecdotal at this point.

But resources are on the horizon. A forthcoming book on the subject, titled "A Really Good Day: How Microdosing Made a Mega Difference in my Mood, My Marriage and My Life," was written by Ayelet Waldman. She says that, many days, she forgets she's taken LSD, and just ends up in the evening realizing she had a really good day.

*From the article here :
 
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Psychedelics linked to better physical health, study*

by Kristi Pahr | LUCID | 6 Apr 2021

Over the last decade, there has been promising research into the benefits of psychedelics for mental health. However, markedly less attention has been paid to their impact on the health of the body. A recent study published in the Journal of Psychopharmacology suggests a positive correlation between the use of psychedelics and improved physical health.

Researchers analyzed data compiled through the National Survey on Drug Use and Health from 2015 to 2018. About 14% of the 171,766 adult respondents reported past psychedelics use. The survey also asked respondents to self-report physical health characteristics such as body mass index, perceived overall health, and cancer or heart conditions within the previous 12 months.

Not only did those who had previously used psychedelics report fewer instances of obesity, they also enjoyed better overall health compared to those who said they’d never used psychedelic substances. Similarly, a decreased incidence of cancer and heart problems was noted in those with past psychedelic experience.

“The association between lifetime classic psychedelic use and having a heart condition and/or cancer in the past 12 months approached conventional levels of significance, with lower odds of having a heart condition and/or cancer in the past 12 months for respondents who had tried a classic psychedelic at least once,” wrote the study authors.

Although the study findings show an undeniable correlation, the cause has not been determined.

“While the acute transcendent experience occasioned by classic psychedelics may presumably induce long-term changes in health behaviour that contribute to better physical health, it is plausible that there are other key mechanisms through which classic psychedelics could influence physical health,” write the study authors. “Including improvements on various indices of mental health beyond the simple absence of psychological distress.”

“The findings suggest that lifetime classic psychedelic use is associated with a range of physical health outcomes. However, caution should be exercised in inferring causality,”
Otto Simonsson of the University of Oxford, co-author of the study, told PsyPost. He explained to Lucid News that the findings were in line with their hypothesis, but more research is necessary to determine causality.

One limitation of the study was that the data was not controlled for “frequency of classic psychedelic use, dose used or context of use. The present study could therefore not evaluate frequency, dose or context-specific relationships between classic psychedelic use and physical health markers.”

Simonsson stressed that more research is necessary. It is yet undetermined whether the use of psychedelics is responsible for better overall health or, conversely, if healthier people choose to use psychedelics. Similarly, the mechanism of action that results in improved health is unclear, and further research is needed to determine the cause-and-effect relationship.

“Our results will hopefully serve as a springboard for rigorous randomized controlled trials on the long-term effects of classic psychedelics on physical health outcomes,” said Simonsson.

*From the article here :
 
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Mike Tyson: ‘I believe if I’d been introduced to the benefit of psychedelics early
in my professional career, I would have been a lot more stable.’


‘I’m a lighter me’: Can Mike Tyson and psychedelics help boxers with brain trauma?

The former heavyweight champion says psychedelics would have helped him with his mental health during his career. Some scientists and companies agree.

by Ben Wyatt | The Guardian | 14 Jun 2021

The peyote cactus is central to many of the rituals of the indigenous Huichol tribe of Mexico. The bright colors and dreamy symbols of their yarn paintings are said to be inspired by the hallucinations experienced by ingesting the mescaline-rich plant in shamanic rituals.

“They do these beautiful creations with beads, paint and sculpture. Peyote, they say. enables them to communicate with the 'gods for the design.' I respect that,” says Mauricio Sulaimán, the Mexican-born president of the World Boxing Council [WBC].

It’s a statement that may help explain the WBC’s recent and, some may argue, unlikely partnership with Wesana Health, the Chicago-based biotech company that is developing psychedelic medicine for the treatment of repetitive traumatic brain injury.

For a governing body whose own Clean Boxing Program demands random drug testing of all of its fighters even the slightest association with a substance still classed as an illegal narcotic by the US government is quite a move. For Sulaimán though, the decision was simple.

“We have so little knowledge of what’s in the brain, so you have to be open to find ways to make boxing and sports safer [and] what can be used to cure,” he says.

The word “cure” is Sulaimán’s optimistic shorthand for the development of any treatment for the brain injuries that have blighted boxing for its long and bruising history. And for a man who has spent his life in the company of those putting their head in harm’s way, the experience of such mental degradation was all too familiar.

“Tommy Hearns struggles with his speech these days. I spent many, many intimate moments with Muhammad Ali, but the memory that sticks out is Raúl ‘El Raton’ Macías,” Suleimán says, of the man considered by many as Mexico’s first boxing idol.

“We were at the dinner for our induction into the Boxing Hall of Fame. And in the middle of eating, he stood up and he said: ‘I’m going home now. I’m going to walk home.’ You know, he lived in Mexico City and we were in New York.”

It was his personal experience around those with brain trauma that made the story of Wesana Health’s CEO Daniel Carcillo all the more compelling to Suleimán.

Carcillo was known as the Car Bomb during his time as an NHL player, so tough was he on the ice. But a career that saw him win two Stanley Cups with the Chicago Blackhawks also delivered countless concussions and subconcussions. So much so that in 2015, at the age of 30, he retired with symptoms including slurred speech, headaches, memory loss, extreme light sensitivity, depression and suicidal ideation. Things only got worse after his skates were put to one side.

“I just couldn’t control or understand what was happening to me,” Carcillo says.

Three weeks into planning how to take his own life he decided to try psilocybin, the active ingredient found in magic mushrooms, for the first time. Under supervision he took a high dosage that allowed him to confront the trauma in his life.

From the brink of suicide, Carcillo says he is now symptom free, the life-changing nature of his psychedelic treatment providing inspiration for the business he co-founded last year. By taking advantage of new laws in some states of America that have legalized psychedelics for medicinal use, Wesana hope to develop a prescription drug that could help treat degenerative brain conditions suffered by athletes.

There are caveats, of course. After all, Carcillo has good reason to talk up his own story of recovery, especially given the recent flotation of Wesana on the Canadian stock exchange. And with a theoretical product which, at best, is years away from entering the marketplace, what’s to say his good health isn’t down to a placebo effect which the WBC has cynically jumped on to be portrayed in a more caring light?

“His recovery sounds viable and doesn’t surprise me,” says Matthew W Johnson, professor of psychiatry and behavioral sciences at Johns Hopkins University and an associate director of their world-leading center for psychedelic and consciousness research. “In our controlled trials, success rates look really good. It’s not uncommon for the people in our sessions to have life-changing experiences with long-lasting effect.”

As one of the most published scientists on the effects of psychedelics, Johnson explains the medicine is potentially working on two levels.

“There’s depression and addiction treatment … where a number of published studies have shown psychedelic treatment to be extremely promising in comparison with SSRIs like prozac. The other category, though, is neurological.”

Johnson explains studies like those conducted by the University of California, have found psychedelic treatments to induce neuroplastic effects in brains of rats.

“Their brains seem to be rewiring and healing,” he says of the exploratory work that has not yet been tested on humans.

While Johnson is careful not to encourage any use of psychedelics outside of research environments, or to suggest their ability to rebuild brains is anything other than theoretical, he remains excited by the potential the future offers.

“I think it’s viable and worthy of more scientific exploration. Psilocybin is going to be approved for depression treatment, within the next five years, or maybe less, in my opinion,” he says. “I think it could be a revolution in psychiatry, though it’s not going to be for everyone.”

One of those it may never appeal to is Sergio “The Latin Snake” Mora. Typical of many fighters, he was careful about what he put inside his body during his boxing career.

“I don’t even like taking Advil,” says Mora, who retired from boxing in 2020. “I grew up that way: didn’t drink soda. Now, you might tell me it’s a mushroom, it’s a natural plant that grows but I still won’t take it. I smoked pot one time when I was 13 and I said, what the hell was that?”

Pain became something to manage during his 36-fight career, according to Mora, who remembers urinating blood on more than one occasion after bouts where he’d taken shots to the body. And it’s this attitude, so hardwired in fighters, that often makes treatment of mental health challenging. In the United States, this is often exacerbated by the fact that few fighters have medical insurance to cover regular heath examinations.

It demonstrates the challenge even a powerful body like the WBC might have in changing the minds of its members.

Wesana hope that recruiting one of the greatest fighters of all time, Mike Tyson, as an advisor to their board may help with this task.

“I believe if I’d been introduced to the benefit of psychedelics for therapeutic use early in my professional career, I would have been a lot more stable in life,” Tyson told the Guardian via email. “I had a lot of public outbursts and they were all mental illness related. Prescription drugs meant I didn’t feel like myself but with psychedelics I feel I’m a happier, lighter version of me.”

It’s a sentiment that resonates with Carcillo, who struggled to explain his own symptoms to loved ones when he retired.

“One thing that not a lot of people talk about is supporting the families of former fighters. Understanding these symptoms, and understanding that your spouse does not want to be this way. Offering them support is something that we’re passionate about, too,” he says.

Tyson says psychedelics have helped ease the blows he took in the ring and during sparring session but other greats like Joe Louis and Sugar Ray Robinson died suffering the mental effects of their beatings. But Tyson may prove to be the first of many boxing veterans who take part in psychedelic studies in the future.

“We can help former fighters by inputting them into clinical trials, understanding more about how subconcussive and concussive impacts affect pathology … and the psychological ailments that many athletes suffer,” says Carcillo. “Not just post-event, but with programs that will focus on human performance aspect too; how much we can get out of these monkey suits of ours.”

For Sulaimán, Carcillo’s progressive plans complement the WBC’s three-decade-long, multimillion dollar funding of UCLA’s world-leading concussion and head trauma research.

“We have the boxers ready to participate,” he says. “We have our medical committee and research teams ready. So we’re just waiting to see what were all these leads.”

The shamans of the Huichol tribe would surely approve.

 
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Psychedelics and Surfing

by Haley Noble | Psychedelic Sandwich | 17 Jun 2021

If asked to conjure up a mental image of a surfer there are plenty of stereotypes to draw on like long hair, maybe lives in a van and smokes weed. Like most stereotypes, this view is myopic and surfing has evolved from a fringe counterculture activity to a sport worthy of a place in the Olympics. The lore surrounding catching waves and enjoying psychoactive substances is not unfounded as the roots of surf culture lie in the narrative of hopping fences and giving the finger to the establishment. As more research points towards the potential medicinal benefits, the stigma surrounding plant medicines lightens enough for all people — including surfers — to explore the benefits of psychedelics. So, are there advantages in combining psychedelics and surfing, specifically? Let’s get into it below.

History of surfing

Surfing originated in the tropical oceans of Polynesia hundreds of years before it appeared in the colonial writings of William Anderson in 1777. What started as riding waves on canoes got honed over generations until the northernmost Polynesian islands — the Hawaiian islands — crafted finless wooden slabs reminiscent of today’s surfboards. The earliest Hawaiian surfers were after more than the thrill of getting barrelled as surfing held spiritual significance. Ceremonial rules governed every aspect of surfing, from deciding what tree to make boards from and praying to the gods for waves and protection.

Another fixture of Polynesian religious practices was the consumption of kava root. Thought to be brought over from the ancestral homelands by the gods, kava was a sacred part of Hawaiian religious ceremonies. At first, only community members of high social standing were permitted to consume it but kava root tea quickly became a commonplace beverage for all members of Hawaiian society. Apart from helping connect the drinker to the divine, the tea enhanced mental clarity, relaxation and focus.

Upon their arrival to the islands in 1820, white missionaries demonized Hawaiian spiritual practices, including surfing. Bringing with them disease and chaos, colonists decimated the Hawaiian population over the following decades, overthrowing Queen Lili’uokalani in 1893 and leading to the United States annexation of Hawaii in 1898.

The loss of independence was a horrific blow to the Hawaiian people, commencing a native-led revival of surfing in the following years. This revival was unfortunately co-opted by colonizers like Alexander Hume Ford. A former South Carolinian, Ford saw this surfing revival as a way to draw tourists and potential settlers to the islands. He promoted the activity to white American and Australian audiences and made a lasting impact on the surf world.

The surge in surfing inspired Hawaiian-born George Freeth to take up the sport and bring surfing demonstrations to the beaches of Southern California. Not long after, swimmer Duke Kahanamoku wowed the people of Australia and New Zealand with his surfing whilst competing in the 1914 Olympics. Leaving behind its roots in Hawaiian and Polynesian culture, surfing was now a growing industry in California and Australia.

Surfing in the 60s

In 1961, the United States Surfing Association was founded as the first professional surfing organization. Surfing at the time was flush with psychedelics. The Brotherhood of Eternal Love — a group of surfers producing and distributing the iconic Orange Sunshine acid — dosed the entire Southern California area and helped establish the connection between surfing and psychedelics. At the time, surfing was associated with the hippie movements occurring throughout California and therefore the reputations of debauchery associated with the long-haired dropouts.

Timothy Leary spoke of the connections between acid trips and the meditative experience of surfing. A surfer himself, he believed the merging of brain, body and nature in the ocean was the perfect vehicle to tune into the interconnectedness of the universe. By tapping into the rhythms of the ocean and flowing along with energy that has traveled thousands of miles, surfers are able to connect with the natural world and achieve an altered consciousness not unlike a psychedelic trip.

Surfing in the 70s

The 1970s brought about a shift in surf culture. Where most shapers relied on the tried and true longboards of earlier decades, the 1970s brought about the desire for shorter, high-performance surfboards. The high-performance shapes allowed short boarders to cut back across the face of the wave, whipping their boards from horizontal to vertical in ways unattainable on a ten-foot longboard.

The ‘70s marked the beginnings of the War on Drugs and the public opinion of psychedelic use shifted towards fear and penalization. For surfers, this did not help their reputation amongst more conservative communities. The stigmatization of surfers as lazy non-contributors influenced the rise of localism during this time. Especially in lower-income areas, surfers pushed back against outsiders and leaned into the rebellion and freedom that came along with the popular conceptions of surfing. No longer the free-loving hippies of the ‘60s, surfers worked to legitimize their craft as a sport. In 1976 the World Surf League was formed.

The 1970s music culture of “sex, drugs and rock and roll” also affected the surfing world. Substance use grew as more young professional surfers joined the competition circuit. The stress that comes along with money, fame and notoriety can be a risk factor for substance abuse and the surfing community did not escape the tragedies of death and loss.

Modern surfing and psychedelics

Over the following decades, the surfing industry grew into the 20 billion dollar industry it is today. Surfing’s reputation as a worthy and healthful pastime took time to free itself from the misconceptions and truths of its history. Prominent voices in the surfing community push back against the idea that surfing equates to substance use. Respected members of the surf community like Dan Malloy, Rob Machado and Bethany Hamilton speak of the dangers of drug use. However, as the conversation around plant medicine shifts, so do the attitudes surrounding psychedelics.

Kelly Slater, arguably the greatest surfer of all time, spoke out against drug use of any kind during his rise to fame in the ‘80s and ‘90s. Notably telling reporters about wanting to beat someone up who offered him a tab of acid when he was a teenager. Today he sings a different tune, testifying that plant medicines, specifically, ayahuasca have changed his life and allowed him to heal past emotional wounds.

New research points to the connections between LSD and high-adrenaline action sports. The rebellious connotation of extreme outdoor sports allows for more leniency surrounding other “risky” behavior. This could explain the connection between psychedelic use in board sports, mountain biking and climbing. While on LSD, researchers have found evidence for increased reaction time, improved balance and strengthened endurance — all helpful tools for an action sport.

Do psychedelics and surfing go together?

Both psychedelics and surfing mean different things to different people. Surfing is an individual sport. Though community exists, it is up to each surfer to define their relationship with an activity much more nuanced than sitting on a board in the ocean. What type of board do they prefer? What type of waves? What type of feeling are they searching for?

Psychedelic experiences are also individual explorations of shifted perception and consciousness. People react differently and get various things out of their psychedelic experiences. For better or worse, surfing and psychedelics seem to remain intertwined as the cultural dialogue continues to change. Even traditional practices find their way into the modern surf world. During the opening ceremonies of the Volcom Fiji Pro in 2012, all competitors took part in traditional kava practices alongside their Polynesian hosts. Recognizing and respecting history promotes progress. As for psychedelics, they haven’t seen their last days in the water.

 
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Studying Ibogaine and 5-MeO-DMT for Traumatic Brain Injuries, interview

by Wesley Thoricatha | Psychedelic Times | 3 Jun 2021

Amber Capone is the co-founder and Executive Director of Veterans Exploring Treatment Solutions (VETS), where she and her husband Marcus Capone have led a charge to help special forces veterans connect with psychedelic treatments. Marcus is an ex-Navy SEAL who experienced traumatic brain injury during his time in the military, and was only able to find lasting healing with ibogaine and 5-MeO-DMT. Since then, Amber and Marcus have done their best to spread the word and raise money to help other veterans find effective treatments, and more recently, to encourage scientific study of these substances.

Amber, in our last interview you alluded to studies that your organization is involved in. Can you share some more details about that? Do these studies involve both ibogaine and 5-MeO-DMT?

Our first goal after Marcus’ therapy was for 12 other veterans to have a similar positive experience, and for those results to last for a 12 month period. That was easy. The second was to help 100 veterans and involve institutional review board (IRB) research. We did that and it was published in July of 2020.

The results were incredible. It was looking at suicidality, depression, substance use, and cognition. It was the first time, to my knowledge, that cognition was measured in a psychedelic study. Psychedelics have historically been researched for other psychological issues such as anxiety, depression, addiction, and so on, but the cognition piece was really significant to me. I insisted that it be included in the measures, because that was one of the biggest takeaways for me after Marcus’ treatment.

Traumatic brain injury (TBI) is the signature injury of both wars (Iraq and Afghanistan), yet it is not talked about that much because it can be very difficult to diagnose, let alone treat or cure. Generally veterans will get a bandaid PTSD diagnosis, and be prescribed a slew of medications. And in many cases, these medications compound the struggle and make things markedly more difficult for the veteran. Marcus at one point was on upwards of ten medications, and it seemed like as time went on, he would need a new medication to combat one of his existing medications, to combat the side effect of another medication, and so on. He was prescribed something to sleep, something to wake up, something for depression, something for mood- it was a nightmare. He was struggling cognitively to a point where he would forget to take these things, which could create a secondary nightmare because all the timing was off.

The TBI and brain component of veteran struggles is where our focus lies. We definitely believe that there are many veterans struggling with PTSD, and I’m not saying that special forces veterans don’t have PTSD, but we’re just choosing to put more of an emphasis on traumatic brain injury because this was so important for us and it remains largely unexplored. The retrospective study that was released showed a very significant improvement in cognition, and 96% of the participants said it was far better than any previous treatment they had tried.

Wow, that is a profound statistic. It must be so cool to see these things come to fruition after all your hard work.

It is, I was just talking to Marcus about this the other day, all the work and heart that goes into this. For every dollar that we take in there are scores of veterans fighting for it, and my heart breaks at the thought of having to say no to someone in need. It’s not a business, it’s a heart led effort, so it’s very difficult. I’ve given a lot of myself so that we can help more veterans, and I sometimes wonder how that can be more sustainable. We need to add organizational leverage and put the oxygen mask on the org a bit, but as exposure grows, so does demand. So we really need increased fundraising so that we can have more runway.

Absolutely. Are there any other studies that you have coming up?

Yes, so the first one we talked about was a retrospective study, and of course it’s not ideal to solely rely on that kind of research, so we are doing a prospective study of that same combo, ibogaine and 5-MeO-DMT. We expect that that study will be published sometime in late 2021.

We’re also kicking off a study partnership with Stanford University that is going to be looking at ibogaine for TBI. It will be the first ever study of its kind linking ibogaine to TBI in 30 participants, and the study will involve both FMRI scans of the brain as well as a series of other measures. This data will be collected before the treatment, immediately after treatment, and then a few weeks later. There’s a link to that study at clinicaltrials.gov.

We’re really excited to kick that off because it will have an emphasis on TBI and blast injury, in particular. Interface astroglial scarring and chronic traumatic encephalopathy (CTE) are the two phenomena frequently found in veteran’s brains, especially special forces, due to blasts and concussive and subconcussive events, which create microscopic injury and potentially degeneration in the brain. Ibogaine may potentially be useful for treating that. It is the only substance known to produce GDNF in the brain- Glial Derived Neurotrophic Factor- which promotes the growth of new glial cells. Who knows if clinical trials are in the future, but this is a very exciting first step.

 
Psychedelics and Sports: Can They Propel Athletes to Unprecedented Pinnacles of Ability?



Psychedelics and Sports: Can they propel athletes to unprecedented pinnacles of ability?

by Kiki Dyon | Psychedelic Spotlight | 20 Oct 2021

While scientific literature on athleticism and psychedelics is still in its embryonic stages, there’s a deep well of anecdotal evidence suggesting that psychedelics could bring athletes to new peaks of performance.

On the heels of sprawling cannabis legalization throughout North America, all eyes are hungrily hooked on the slow but certain legalization of psilocybin. No self-improvement trend has ever captivated every corner of the internet the way microdosing has.

The echoing accounts of those supplementing studious, sportive, and career-climbing endeavors with psychedelics have induced mania in the everymen. All groups, from existentially-exhausted mothers to weekend-warrior endurance athletes to university students, are eager to microdose their way to enhanced cognition.

Or, as Dr. Fey, a Western New York physical therapist and psychonaut, phrases it for Psychedelic Spotlight, “experimental success-seekers are using small amounts of psychedelics to propel them to unprecedented pinnacles of ability, and it’s working.”

Here we focus on a newly-researched niche: athletic performance and psychedelics.

A no-hitter on LSD

Where should we start? With the infamous, LSD-fueled no-hitter, of course.

The century-spanning chronicles of baseball are charged with oddities and accomplishments, but few are as iconic as when a 25-year-old right-handed starter for the Pittsburgh Pirates named Dock Ellis threw a no-hitter while tripping on LSD.

Dock Ellis recounted the drugged-out day in great detail to NPR before his death, and No Mas used the audio from the interview to create a fascinating short film. The story begins with Ellis partying with his friends the day before the game. The holy trinity –– alcohol, acid, and marijuana –– were involved. Ellis passed out and, upon waking up from his nap, took more acid, confusedly believing it was still the same day. He recalls thinking he was in the clear before a friend informed him that he had to pitch in just hours. So, he hopped on a plane and fulfilled his obligation with LSD lighting up his senses.

“I started having a crazy idea in the fourth inning that Richard Nixon was the home plate umpire,” Ellis recounted in an interview years later. “And once I thought I was pitching a baseball to Jimi Hendrix, who to me was holding a guitar and swinging it over the plate.”

The film and story are incredibly entertaining, but like most tales that seem too fantastical to be true –– there’s just one lingering question: did it actually happen?
Well, that depends who you ask.

Bob Smizik, who covered the Pirates from 1972-77 for the Pittsburgh Press, is a believer. While he didn’t cover the game, he was the first writer to break the legend of the LSD no-hitter.

In the story, Smizik even included a quote from a Pittsburgh-area psychologist, Dr. Maurice Cerul, to lend the story a dash of credibility:

“If he had a good trip, he could have done his task without problems. As a matter of fact, he could have performed even better. It’s within the realm of possibility. But LSD should not be used to enhance one’s athletic ability.”

However, that quote was given decades ago, when psychedelic use was still a big no-no and counterculture activity. Now, researchers are abandoning their hesitancy to proclaim that using psychedelics to enhance athletic performance exists in a good or bad binary.

Psychedelics and Endurance Sports

When the topic of performance-enhancing drugs rears its head, the usual suspects—steroids, stimulants, etc.—are always mentioned. Psychedelics, meanwhile, are often overlooked.

Okay, fair enough, it seems like an easy assumption that psychedelic drugs aren’t performance-enhancing. But as James Oroc explained in his legendary essay, extreme sports and the underground psychedelic scene have a surprising decades-long relationship.

“According to the combined reports of 40 years of use by the extreme sports underground, LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration until you experience “tunnel vision”, and make you impervious to weakness or pain,” Oroc claims. “LSD’s effects in these regards are in fact legendary, universal, and without dispute.”

More recently, a citizen scientist wrote an extensive self-study for Borealism chronicling the effect of microdosing mushrooms on athletic performance. In his report, he claims, “psilocybin provokes a more immersed engagement with any activity; in this context, it amounted to a much more motivated sense of engagement with swimming and running as it displaced the perception of discomfort, pain, and fatigue.”

While he insists that there appears to be a performance-enhancing outcome, he acknowledges that it’s hard to know how much a placebo effect is in play.

“This [performance-enhancing] effect, as expected, is more psychological than physiological, though it will be argued that there is little need to differentiate between the mind and the body when it comes to improving sportive ability in this sort of context,” the researcher writes.

Moreover, the performance enhancement may only be relevant at the highest echelons of professional sport, where everyone is first-rate, and the difference between winning and losing is a game of millimeters or milliseconds.

Sports psychologist Stan Beecham explains, “The reality is not that [top athletes] think differently. It’s that they don’t think. It’s the absence of thought. It’s the absence of cognition. It’s the absence of emotion. That really is the advantage.”

The Bottom Line

While the evidence isn’t ironclad, it is accumulating.

With the potential of psilocybin legalization on the horizon, more robust research on psychedelics and exercise performance is promised. Dr. Fey is hopeful, telling Psychedelic Spotlight, “Soon, we’ll get a clearer picture of the broad effects of these psychedelics on performance. Sports have always explored the outer limits of human potential, and as athletes start reaching even higher levels of precision, they’ll search for whatever advantage they can get.”

But for now, urban legend and anecdotal evidence are enough to convince, or at least entertain, many.

 
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Psychedelics and Extreme Sports

by James Oroc

According to the legends of this tight-knit underground, many incredible feats having been accomplished by modern extreme-athletes while under the influence of psychedelics. LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration...and make you impervious to weakness or pain.

For those unfamiliar with the effects of psychedelics, the title of this article may seem like a contradiction – for what connection could there possibly be between these psychedelic compounds and extreme sports? Based on the tangled reputation that LSD has had since the mid-1960’s it would seem impossible to believe that various experienced individuals have climbed some of the hardest big walls in Yosemite, heli-skied first descents off Alaskan peaks, competed in world-class snowboarding competitions, raced motocross bikes, surfed enormous Hawaiian waves, flown hang-gliders above 18,000 feet, or climbed remote peaks in the Rockies, the Alps, the Andes, and even above 8000 meters in the Himalayas – all while under the influence of LSD.

However, in the underground culture of extreme sports, the use of LSD or psilocybin while skiing, snowboarding, mountain biking, surfing, skateboarding, etc., is in fact common throughout North American ski and sports towns, where they enjoy an almost sacred reputation. According to the legends of this tight-knit underground, many incredible feats having been accomplished by modern extreme athletes while under the influence of psychedelics.

Popular perception about the disabling effects of psychedelics and their use in the extreme sports community is mostly a matter of dosage and historical familiarity. LSD is extraordinarily potent - effective on the human physiology in the millionths of grams (mcg), and very small differences in dosage can lead to dramatically different effects. In the first decade of LSD research it was commonly accepted that the “LSD intoxication” occurred when dosing over 200mcg. At the lower dosages, a state was known as “psycholytic” was also recognized, where in may cases cognitive functioning, emotional balance, and physical stamina were actually found to be improved.

This recognition of the varying effects of LSD was lost after the popular media demonized LSD with the help of the various myths and excesses of the “1960s Love Generation.” When LSD made the jump from the clinic to the underground, its early explorers were universally fascinated with the higher dosage entheogenic experience, while the more subtle effects at lower dosages were largely forgotten or ignored. The first “street” LSD in the 1960’s was generally between 250 and 500mcg — a potency powerful enough to guarantee the casual user a truly psychedelic experience.

LSD is somewhat unusual, however, in that a user can build a fast tolerance to the compound after regular (daily use) and while one’s initial experiences on even a single dose can be dramatic, before long veteran psychonauts may be increasing their own dosage tenfold – thus requiring much stronger “hits” than the average user. It was the high dosage of this early street LSD that in combination with the complete ignorance of its early users that would be responsible for the high number of “acid casualties” that gave LSD its fearsome reputation. However, by the 1980’s both Deadheads and the rave generation had realized to drop the dosage of street LSD to between 100-125mcg, while these days a hit may be as low as 50mcg—or as little as ten percent as powerful as a hit of 1960’s LSD. Which is a dosage well below the true psychedelic threshold for most people, and for an experienced user suitably inclined, can certainly be calculated to fall within the forgotten “psycholytic” category."

There was always a strong contingent of “experienced psychedelic users” among the extreme sports community due to the little-realized fact that the seeds of the extreme sports revolution were actually planted with the dismantling and dispersal of Psychedelic Culture in the late 1960’s and early 1970’s. As countless numbers of counterculture refuges left the major cities and moved out to small towns in the country in the “Back to the Land” movement, most were looking for new paths to fulfillment after the spectacular promises of the brief “Psychedelic Age” had failed and a new age of uppers and downers was emerging.

They were faced with an obviously dangerous downturn in what was now being universally called the “drug culture.” First heroin, and then, cocaine, dramatically increased in popularity, which marked the beginning of our urban society’s more than thirty year-old epidemic of cocaine and amphetamine abuse. A few turned to the traditions of Christianity, Islam, Eastern, or New Age religions, while many others, perhaps less institutionally inclined, went to small coastal towns in California, Oregon, or even Hawaii to surf. Or they landed in the numerous small towns in the Rockies from Montana to New Mexico that were being developed as ski areas at that time.

These “hippies” bought with them a newly found cultural respect for the land, which had come directly from the use of psychedelics, since the use of psychedelics in nature inevitably increases the spiritual appreciation of one’s role in nature, and of Nature itself. (There are many commentators today who believe that the modern environmental movement was born out of the fact that 25 million people took LSD in the late 1960s). They also had an adventurous attitude toward the land, derived from a general fascination with the Plains Indians and the Wild West era, and from the naturalist vision of the American wilderness that Walt Whitman, Thoreau, and especially Jack Kerouac espoused - the philosophy that one could somehow “find oneself” out among the wilds of America.

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At the same time as this sudden influx of these “freaks” to the beaches, deserts, and mountains of the world, technological advances in what were considered minor cult-like sports were suddenly allowing ordinary individuals unprecedented access to the wildernesses of the world. In the mountains, the ocean, and even the air, a new kind of athlete took the concept of “finding oneself in the wilds” to a whole new definition. The invention of these highly individualistic sports (surfing, skateboarding, snowboarding, BASE jumping, tow-in surfing, etc.) that sought to use existing terrain in new and inventive ways generally raised the ire of the status quo, and so most “extreme sports” begin life as “outlaw sports” of some kind or another, with their participants regarded as rebels.

The attraction of these types of sports for the newly arrived psychedelic era refugees is obvious, and most of the leading figures of surfing, rock climbing, back country skiing, hang gliding, etc., of this era were clearly cultural rebels living well outside of the norms of society. For this particular branch of the psychedelic tree, the oceans, deserts, and great mountains of the world were now being recognized as the ultimate “set and setting” – a realization common to mystics and saddhus since the beginning of recorded time.

Thanks to the sudden exponential growth of the worldwide leisure industry towards the end of the 1970s, becoming a climbing, skiing, or surfing “bum” became the easiest way of dropping out of contemporary society, a socially healthier alternative to the free love communes of the previous decade that still allowed one to smoke pot, take psychedelics, and mostly fly under the cultural radar. By the 1980s a good portion of any American ski town (and especially the leather-booted telemark skiers) were Dead-heads, and the most effective LSD network in the country–while many other less obvious skiers and climbers still kept the tradition of using pot (a remarkable natural analgesic), LSD, and mushrooms in the mountains alive, where the mountains themselves acted as natural shields from prying eyes.

After the invention of snowboarding, mountain biking, and to a lesser extent paragliding, in the 1980s, virtually all of the newly named “extreme sports” experienced a rapid growth of popularity in the mid 1990s. This resulted in a corresponding growth in the populations of these same small ski and sports towns. Between 1992 and 1997 MTV Sports was one of the most popular shows on cable television, as it glorified the emerging “extreme-sports” to its youthful audience and established the “grunge” and hip-hop music it was promoting as the “in” sound of the now exploding snowboarder population.

"If you start asking about sporting feats accomplished on psychedelics in pretty much any bar in a ski town, you will hear some fine tales..."

The emerging electronic (rave) music of the same time period also appealed to the naturally rebellious nature of extreme athletes and introduced that culture to Burning Man from its very inception, further reinforcing the knowledge of modern psychedelic culture in what are often remote mountain towns. (“Black Rock City” got its name in 1995, the same summer as the first X Games.) Many Western ski towns now have a resident “Burner” population, much in the same way they had “hippy” or “freak” population in the early 1970s, and these small towns generally remain more liberally-minded than other towns of similar size in America.

This entwined relationship between the cultures of psychedelics and extreme sports has in fact been there since the beginning, with what is perhaps the original extreme sport, the much mythologized sport of surfing. After the fallout of 1967-68, when San Francisco and the Haight-Ashbury became overrun, and its original hipster founders abandoned it, the Southern Californian surfing town of Laguna Beach became the defacto center of the psychedelic world when a group of diehard surfers – known as the Brotherhood of Love – became the world’s first LSD cartel.

Along with the smuggling of tons of hashish from Afghanistan to fund their operation, they were responsible for distributing tens of millions of hits of Orange Sunshine LSD. In explaining the connection between LSD and surfing, early Brotherhood member Eddie Padilla remarks on the practical side of a culture based on pot and psychedelics use:

“The effect of the LSD we were taking was starting to demand a higher quality lifestyle, food-wise and in every way. All these surfer people had that lifestyle already in place. To surf, you had to remain sober and be more in tune with nature. Don’t get too screwed up, because the surf may be good tomorrow.”

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In this explanation, Eddie Padilla hits on half of the real physical reason why psychedelics have always been a part of extreme sports culture, in that psychedelic use is not only more inspiring in the wilderness, but it is also eminently more practical. LSD can easily be a 10 to 14 hour experience, which is too long of a trip for most people, and especially if it is taken at night. If it is taken in the morning, however, and one has the voluminous expanses of the ocean, the deserts, or mountains of the world to roam and contemplate, then the length of an LSD trip is rarely a problem since it will also start to fade with the end of the light of the day.

If one keeps hydrated, and the LSD trip is kept within the regular biorhythms of the user to allow normal hours of sleep, then this “trip” can in truth be one of the least physically debilitating altered states experiences available, with little or no discernible “hangover” – ridiculously so when compared to the debilitating effects of cocaine or alcohol and the extreme hangover they bring. The non-addictive and nonphysically debilitating qualities of psychedelics are of course rarely touted by the popular media, but are well known among communities that are familiar with them, and the nontoxic qualities of psychedelics are half of the physical reason for their enduring appeal among extreme athletes.

The other half of this physical reason that “psychedelic drugs” are so popular with extreme athletes is due to their previously noted psycholytic effects at the correct dosages. Virtually all athletes who learn to use LSD at psycholytic dosages believe that the use of these compounds improves both their stamina and their abilities. According to the combined reports of 40 years of use by the extreme sports underground, LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration until you experience “tunnel vision,” and make you impervious to weakness or pain. LSD’s effects in these regards among the extreme sport community are in fact legendary, universal, and without dispute.

It is interesting to note the similarities between the recollection of these athletic feats while in this psycholytic state, and descriptions that professional athletes give of “Being in the Zone,” a mythical heightened “state” of neo-perfection where athletes report very psychedelic effects such as time slowing down and extraordinary feats of instantaneous non-thinking coordination. Athletes and normal individuals also claim the same effects in moments of heightened adrenaline – the classic fight or flight response. As LSD research returns to the mainstream in the United States, further investigation into the claims of athletes, such as the extreme sports underground, could result in a radically different perception for the variety of uses of psychedelics.

As an extreme sports athlete, journalist, and advocate since the late 1980s, and a former resident of the Rockies for over a decade, I have witnessed tales of numerous incredible feats on psychedelics in the mountains – none of which, unfortunately, I have permission to tell of here. However, after MAPS asked me to write this article earlier this year, I started asking around for other people’s stories. If you start asking about sporting feats accomplished on psychedelics in pretty much any bar in a ski town, you will here some fine tales. I heard of a hang glider flown tandem off of a mountain top under a full moon with both the pilot and passenger on magic mushrooms, of helicopter skiing in Alaska on LSD when the guide got avalanched off a cliff right in front of the tripping skier, and of radical solo rock or ice climbs of the highest intensity performed on equally radically headfulls of psychedelics. I even heard of someone taking a hit of DMT before they jumped out of an airplane skydiving. (Now that’s crazy!) I also have no doubt that someone rides Slickrock in Moab on mushrooms or LSD probably every single day, and that you couldn’t calculate the number of people who are tripping when it snows in the Rockies. Psychedelic use among extreme sports enthusiasts is simply that prevalent, and has been since the start.

Psychedelics and sports, incredibly, can go together like cheese and bread. An enhanced spiritual appreciation of the natural environment, along with increased stamina and an almost unnatural improvement in balance, are too powerful of a combination not to become sacred among mountain athletes. When I asked a well-known high-altitude climber in Colorado about climbing in the Himalayas on LSD, he just laughed and stated that at high-altitude LSD was like “cheating” since it did such a good job of overcoming fatigue and altitude sickness. He also had no doubt that someone had summited Mount Everest while tripping. But I can see how this could all seem very circumstantial and uncorroborated to someone who is skeptical, so I can offer the single documented example of LSD being used in a truly remarkable sporting achievement. This is not one that comes from the outlaw fringes of the extreme sports, but from baseball, from America’s sport itself.

On June 12th, 1970, the Pittsburgh Pirates starting pitcher, Doc Ellis, threw a no-hitter against the San Diego Padres in a regular major league baseball game, which he admits occurred while he was on LSD. Ellis had thought he was off the pitching roster for that day and so had taken LSD with friends in Los Angeles, only to find out, while high, that he had to pitch a game against the Padres that night.

As Ellis recounted it:

"I can only remember bits and pieces of the game. I was psyched. I had a feeling of euphoria. I was zeroed in on the catcher’s glove, but I didn’t hit the glove too much. I remember hitting a couple of batters and the bases were loaded two or three times. The ball was small sometimes, the ball was large sometimes, sometimes I saw the catcher, sometimes I didn’t. Sometimes I tried to stare the hitter down and throw while I was looking at him. I chewed my gum until it turned to powder. I started having a crazy idea in the fourth inning that Richard Nixon was the home plate umpire, and once I thought I was pitching a baseball to Jimi Hendrix, who to me was holding a guitar and swinging it over the plate."

So for those of you who find it hard to believe that someone can ski, mountain bike, or even fly a hangglider while on psychedelics, I submit to you the well documented case of Doc Ellis, and the fact that a no-hitter in baseball is considered one of the hardest achievements in professional sport; while there have been over 175,000 professional baseball games played since 1900, only 269 no-hitters were pitched between 1879 and 2010. Doc Ellis would go on to be in the World Series with the winning Pirates, and was the starting pitcher for the National League in the All Star Game, but this now-legendary LSD-fueled day was his only no-hitter.

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Athlete and journalist James Oroc has been involved in extreme-sport culture since 1987. In 1993 he made the first flight by a paraglider from the top of the world’s tallest active volcano, (Cotopaxi, Ecuador. The author of Tryptamine Palace: 5-MeO-DMT and the Sonoran Desert Toad; From Burning Man to the Akashic Field (Park Street Press, 2009), Oroc also writes and lectures regularly about entheogens and is the curator of www.DMTsite.com, launched in 2011.

https://maps.org/news-letters/v21n1/v21n1-25to29.pdf
 
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Lamar Odom reveals ‘Ibogaine’ use in explosive new interview

by Mike Walters | BLAST | 20 July 2021

Former ‘Los Angeles Lakers’ star Lamar Odom is opening up about his decision to use powerful psychedelics to treat his long-term drug addiction.

The NBA all-star sat down with ‘The Megan Pormer Show’ on FOX LA in a bombshell new interview to discuss a wide range of topics, including his use of the powerful drug, Ibogaine. As you know, Odom has struggled with substance abuse for the past few years, something that ultimately ended his basketball career.

In the interview, Pormer opened up about her own use of another drug — Ketamine — to treat depression and other ailments. During the discussion, Odom revealed he took Ibogaine that said it was a life-changing decision. Interestingly, Odom confirmed he has also tried Ketamine as a treatment and is currently working on a documentary about his experience.

Lamar described the psychedelic trip as a “healing” experience.

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Lamar Odom takes ‘grandfather of psychedelic drugs’

“I did experiment with another psychedelic drug, Ibogaine, which is like the grandfather of psychedelic drugs, and I think that’s where I had the most spiritual experience…They say the first person you see is someone really close to you in your family,” Odom said in the interview set up by powerhouse media company FAME By Sheeraz.

He continued, “The first person I saw was my cousin Sierra, who at one time, even though I’m young, my grandma and I helped raise her. Her face was big, it was like this close to me. And then I kept hearing my mother’s voice, my grandmother’s voice, and that was of course extremely spiritual that I got to reconnect with their voices…And then I got to see my son. I got to see him at the age he passed away. I got to see him at the age…8 or 9 years old. And then I got to see him at the age he would be now…Just to see him was enough. It was crazy.”

Ibogaine is a psychedelic drug, that preliminary research indicates reportedly may be able to treat drug addiction. It’s derived from the root of an iboga tree in Central Africa, and ibogaine’s effects have been studied by scientists since the CIA got a hold of it in the 1950s.

During the interview, Odom admitted it was a very “strong, strong” drug which he hoped would stop once he started feeling its effects. But, in the end, he believes it was the ultimate healing experience.

In the end, Lamar discussed the passing of his young son and how he died on the same day as the basketball star’s grandmother. It’s clear the traumatic events weighed heavily on him and pushed him down a dark path.

In the bombshell interview, Lamar also discussed his ex-wife Khloe Kardashian and how he would get together with her in a “heartbeat.” The host pressed Odom on his interaction with the ‘KUWTK’ star’s baby daddy — Tristian Thompson — on Instagram after he commented how beautiful she was in a smoking hot picture of KK. “He doesn’t know me,” LO said and claims the situation could have gotten much worse.

 
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Why weren’t psychedelic drugs prohibited in the 2021 Tokyo Olympics?

The truth is that scientists don’t know enough about them. And research into any athletic-enhancing capabilities they may have is lacking.

by Barbara E. Bauer, MS | Psychedelic Science Review | 6 Aug 2021

The 2021 Olympic games in Tokyo, Japan are coming to an end this week with the closing ceremonies scheduled for Sunday at 7:00 AM EST. Last month, controversy erupted surrounding the 1-month suspension of US sprinter Sha’Carri Richardson for testing positive for marijuana.1 Although Ms. Richardson was not using the plant to give her an edge in competition, evidence of it in the bodies of athletes is still prohibited.

Psychedelic Science Review took a closer look at the list of prohibited substances as identified by the World Anti-Doping Agency (WADA) in Montréal, Canada. The WADA publication lists a variety of substances, including cannabinoids, stimulants, and narcotics as prohibited. But interestingly, no psychedelic drugs are mentioned.

But the question arises, do psychedelics even make people better athletes?

Psychedelics and Improved Sports Performance

In 2019, Steven Machek of Baylor University wrote in the Journal of Exercise and Nutrition,​
"Given the propensity of subjective psychedelic benefit, microdosing practice warrants further investigation on its ability to augment athletic endeavors."

His paper provides an overview of the literature on psychedelics and improved athletic performance from both a physiological and psychological perspective. From his work, Machek also concluded that,​
"A preponderance of subjective claims and fervent anecdote indicates psychedelics may enhance mental acuity and subsequent exercise performance."

However, research into the sports-enhancing effects of psychedelics remains at a standstill.

Summary

It appears that insufficient data exist to determine if psychedelics are performance-enhancers and should be on the WADA list. It’s still a very new area of research even from a pharmaceutical and subjective effects standpoint. And apparently, no one in any official capacity is studying their effects on athletic performance. This is another wide-open area of psychedelic science for the curious researcher to study.

 
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Can marijuana make you a better athlete?

by Anahad O’Connor | New York Times | 11 Jul 2021

When Sha’Carri Richardson was denied a spot in the Tokyo Olympics after testing positive for marijuana, it reignited a debate about using cannabis to aid in sports. Does it actually help?

Josiah Hesse, a journalist who lives in Colorado, never voluntarily exercised a day in his life until he turned 30, when he decided to start doing it for health reasons. But right away, he hated working out.

“When I first started running, I couldn’t run a single block,” he said. “It hurt and my lungs burned.”

Then one day he took a cannabis-infused edible before going out for a run and his previously excruciating workout felt euphoric. “I felt like I weighed 50 pounds,” he said. “Running up a hill became an easy, playful experience. With the right soundtrack it was so much fun. It became the highlight of my day.”

Soon, Mr. Hesse met other runners and athletes who described having similar experiences with cannabis. That led him to write “Runner’s High,” scheduled to be published in September, which explores what he calls the “hidden culture” of cannabis use among recreational and elite athletes who routinely engage in stoned workouts. For his book, Mr. Hesse interviewed bodybuilders and endurance athletes who rely on cannabis to stimulate their appetites so they can keep on weight. He spoke to athletes who have claimed it helps them recover from tough workouts, reduces their pain and improves their sleep. But the most common refrain from athletes who use cannabis was that it helped calm their nerves and alleviate anxiety.

“What I heard so often from athletes who use cannabis is the phrase ‘dialed in,’” he said. “They become myopically focused on the task at hand. Any anxiety that they have about thousands or millions of people watching them, about their careers being at stake, or whether that injury from last year is going to hold up — it all melts away.”

When Sha’Carri Richardson, the star American sprinter, was denied a spot in the Tokyo Olympics this month after testing positive for marijuana, it reignited the debate around cannabis and performance enhancement among elite athletes. More broadly, however, is there any value for the average person to mix exercise and pot?

Cannabis is not a performance enhancer.

Although marijuana is prohibited by the World Anti-Doping Agency, there’s no scientific evidence that it can make people bigger, stronger or faster athletes. If anything, cannabis — the scientific name for the hemp plant, from which marijuana is derived — has a reputation for decreasing athletic performance.

Research suggests that, for competitive athletes, cannabis can be a double-edged sword. In some of the earliest studies looking at its effects on exercise, scientists found that when they assigned healthy volunteers to smoke cannabis and then perform strength and exercise tests, the cannabis spiked their heart rates, increased their blood pressure levels and hampered their ability to exercise.

Many of the studies that followed were small, not very rigorous or performed on animals. But overall, their findings suggest that cannabis use does not improve strength or exercise endurance.

“If you look at any test of physical performance, there’s either no data, it’s a wash, or marijuana makes it worse,” said Dr. Michael Joyner, an exercise physiologist and anesthesiologist who studies elite athletes at the Mayo Clinic in Minnesota.

Dr. Joyner said there might be some objective but minor physical benefit of cannabis in certain sports. World Archery, the international federation for the Olympic sport of archery, bans alcohol from competitions because it could help to steady an archer’s hand. Cannabis could potentially offer a similar advantage in sports that require such feats. But there is no real data to support that.

For cannabis users, experts say consider the risks.

There are also some potential health concerns surrounding marijuana, experts say, especially for athletes who smoke it. According to the American Lung Association, marijuana smoke contains many of the same toxins and carcinogens as tobacco smoke. And since marijuana smokers tend to inhale deeply and hold their breath longer than people who smoke cigarettes, they can be exposed to more tar. “Smoking marijuana clearly damages the human lung,” the lung association states. “Regular use leads to chronic bronchitis and can cause an immune-compromised person to be more susceptible to lung infections.”

Scientists say there are mental health risks as well, especially for people who start using cannabis as teenagers or young adults. Studies suggest that early exposure to marijuana can lead people to experiment with harder drugs, and a 2017 report by the prestigious National Academy of Medicine concluded that cannabis use increases the risk of developing schizophrenia and other psychoses. Some people may be more susceptible because of genetics or other factors.

Studies show that cannabis can also worsen people’s reaction time and hamper their decision-making abilities. That can be dangerous in situations where there is a high risk of serious physical injury, whether it is driving a car, lifting heavy weights or cycling along the shoulder of a busy road.

So, why have marijuana workouts become popular?

Still, the potential health risks and lack of evidence for performance benefits have not deterred some athletes and exercise aficionados from exercising while high — and swearing that cannabis enhances their workouts.

In a 2019 study published in the journal PLOS One, 26 percent of 1,161 self-identified athletes, mostly runners, cyclists and triathletes, reported that they were current users of cannabis. Some smoked it, while others consumed it as edibles or rubbed it on their bodies as creams. Around 70 percent of the athletes said that it helped them sleep or alleviated pain stemming from tough workouts and other activities. Almost 60 percent said that it calmed them down.

In another 2019 survey, Angela Bryan, a professor of psychology and neuroscience at the University of Colorado Boulder, and her colleagues recruited about 600 regular cannabis users and quizzed them on their use of the drug. Dr. Bryan suspected that cannabis would make people less physically active. But to her surprise, roughly half of the people in the study said that cannabis motivated them to exercise. More than 80 percent of cannabis users said that they regularly used it around the time of their workouts. Seventy percent said that marijuana increased their enjoyment of exercise, and roughly 80 percent said that it helped them recover.

“It was a pretty strong relationship and pretty common to use cannabis either before or after exercise,” Dr. Bryan said. Studies suggest that cannabis may help some people fall asleep faster, and there is modest but limited evidence from clinical trials that it reduces pain and inflammation. “It’s probably not surprising that people are using it in that context,” she added.

For the most part, research on cannabis and its effects on exercise has been somewhat limited by its status as a Schedule 1 drug.

“The federal legal status means that we can’t have it on campus or prescribe it or even tell people what to use,” Dr. Bryan said. “We are not allowed to give them anything.”

That has constrained Dr. Bryan’s ability to examine more closely how cannabis influences exercise, metabolic health and inflammation, since she cannot bring people to her lab, give them an edible and run experiments on them.

She and her colleagues, however, have devised a way to get around this. Using a mobile lab, they drive to the homes of people who regularly use cannabis, taking blood samples from the subjects and running tests on them before and after they use the drug. “They tell us what they use and then we quantify the THC and CBD in their blood for an objective level,” she said.

Next, the subjects show up at the lab on different days to run on a treadmill, sometimes after they have used marijuana and other times after they’ve abstained. A few things Dr. Bryan and her colleagues are looking into is whether cannabis affects how much pain and pleasure people experience while exercising and whether it influences their perception of time.

“When we talk to endurance athletes who do a four-hour run or bike ride,” she said, “they tell us that cannabis makes the time go faster and it feels less boring.”

 
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Can LSD make you better at sports?

by Rich Haridy | NEW ATLAS | 20 Jul 2021

With the Tokyo Olympics almost upon us, the world’s best athletes are converging on Japan and it seems inevitable the topic of performance-enhancing drugs will at some point rear its head. The usual suspects – steroids, stimulants, etc. – will obviously be closely monitored, but what about other drugs, such as psychedelics, not commonly thought to be performance-enhancing?

Can LSD improve athletic performance? If so, then how? And what does this mean for elite sport in the future?

A no-hitter on acid

One of the most iconic, possibly apocryphal, drug stories of the 20th century is the tale of Pittsburgh Pirates pitcher Dock Ellis throwing a no-hitter while tripping on LSD in 1970. Ellis recounted his story in great detail to NPR shortly before his death, and the audio from that interview was used to create a fantastic short film.

The story goes, Ellis had been partying with friends the day before a big game. Acid, alcohol and marijuana were all involved. Upon waking from a nap, and thinking it was still the same day, Ellis took more acid before a friend informed him he was meant to pitch in a few hours.

Ellis raced to the airport, jumped on a plane, and got to the stadium around four or five hours into the acid trip. His memory of the game is blurry, unsurprisingly, and almost no footage exists from the game to easily verify the incredible story.

“I started having a crazy idea in the fourth inning that Richard Nixon was the home plate umpire,” Ellis recounted in an interview years later. “And once I thought I was pitching a baseball to Jimi Hendrix, who to me was holding a guitar and swinging it over the plate.”

A no-hitter, where a pitcher prevents an opposing team from hitting the ball even once during the course of a game, is a stunningly rare achievement. Since the beginning of Major League Baseball in 1876 only 312 no-hitters have been thrown – and if we believe Ellis’ story, one of those was accomplished while under the influence of LSD.

The World Anti-Doping Agency (WADA) currently does not specifically prohibit the use of classical psychedelics such as LSD or psilocybin in sport. The agency does, however, prohibit pharmacological substances “with no current approval by any governmental regulatory health authority for human therapeutic use”, which would cover psychedelic drugs. Despite this, WADA does not assume these substances are performance-enhancing.

Psychedelics and extreme sports

Sure, it may seem like a fair assumption that psychedelic drugs are not performance-enhancing, at least not in the way we would traditionally expect drugs to be performance-enhancing. But, as legendary journalist James Oroc outlined in an iconic essay, there has long been a strange relationship between underground psychedelic culture and extreme sports.

Oroc’s essay describes the birth of the extreme sports movement in the 1980s as being deeply connected to the psychedelic-era refugees from the late 60s and early 70s. He explains that as the potency of the "street acid” dropped in the 1980s from the powerful dissociative extremes of the 60s, users began to explore what are known as psycholytic doses.

A psycholytic dose of LSD is somewhere between a strong high dose and a microdose. Whereas the goal of microdosing is to ensure the drug is consumed in doses that are not acutely felt, psycholytic dosing is most certainly felt. But, as Oroc explains, this sweet spot of psychedelic consumption is considered by many extreme sports athletes as performance-enhancing, at least anecdotally.

“According to the combined reports of 40 years of use by the extreme sports underground, LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration until you experience “tunnel vision”, and make you impervious to weakness or pain,” Oroc claims. “LSD’s effects in these regards are in fact legendary, universal, and without dispute.”

In 2019 Sarah Rose Siskind ran an ultramarathon on LSD at Burning Man. Siskind intended the experience to be therapeutic, following a traumatic near-death experience at Burning Man the year prior.

Siskind was not unfamiliar with either LSD or ultramarathons and had experimented with shorter runs before the big event to make sure the drug didn’t trigger any dangerous physiological effects in conjunction with the physical exertion.

“I trained physically in that I had been running ultramarathons for the past two and a half years,” Siskind said in a 2019 interview with Psymposia. “And, I trained for the drug intake. I did one training run where I ran 20 miles on LSD, and I found that the main problem was that I ran extraordinarily slowly – I was so distracted by everything. So, I figured it wasn’t a performance-enhancing drug, exactly. But, it certainly wasn’t increasing my risk profile.”

Her description of the experience doesn’t suggest the drug made it easier to run the long marathon. Instead, unsurprisingly, the psychedelic simply amplified what was already an intensely psychological experience. Siskind certainly isn’t the first person to reportedly run an ultramarathon on LSD but it does seem clear psychedelics can be just as much of a performance-hinderer as a performance-enhancer.

These performance-enhancing effects of psychedelics may be “without dispute” in certain underground sub-cultures but it is unlikely an elite athlete would be taking a high dose of LSD before participating in a major gold-medal event in the Olympics.

But what about microdosing?

Performance-enhancing microdosing?

With scientists now beginning to investigate the popular phenomenon of microdosing there are only anecdotes and reports from citizen scientists offering insights into the possible performance-enhancing effect of this behavior. The few published studies on microdosing are decidedly inconclusive and it’s unclear how much the placebo effect plays a role in the popularly reported benefits of microdosing.

Anecdotally, online reports vary from, “I shoot hoops really well” when microdosing psychedelics to, “it slows my reaction speed.” One citizen scientist, documenting the effect of microdosing psilocybin on athletic performance, suggests "there definitely appears to be some kind of performance-enhancing outcome but it is almost impossible to know how much of a placebo effect is at play."

“This [performance-enhancing] effect, as expected, is more psychological than physiological, though it will be argued that there is little need to differentiate between the mind and the body when it comes to improving sportive ability in this sort of context,”
the researcher writes.

And here the performance-enhancing potential of microdosing psychedelics may be relevant for high-level athletes. It is no newsflash to suggest elite sports are as much about training the mind as the body.

Sports psychologist Stan Beecham explains, "when you reach the highest echelons of professional sport, everyone is talented. The difference between winning and losing in an Olympic event often comes down to milliseconds or millimeters."

And in these instances a winning, performance can become more about training the mind than training the body. But Beecham argues top level athletes win by learning how to switch off their minds and get into the flow of the moment.

“The reality is not that [top athletes] think differently,” Beecham said in an interview with Forbes. “It’s that they don’t think. It’s the absence of thought. It’s the absence of cognition. It’s the absence of emotion. That really is the advantage.”

When James Oroc wrote about the relationship between extreme sports and LSD he referred to the similarities in the way professional athletes talk of “being in the zone” and recollections of people on psychedelics.

“It is interesting to note the similarities between the recollection of these athletic feats while in this psycholytic state, and descriptions that professional athletes give of 'Being in the Zone', a mythical heightened “state” of neo-perfection where athletes report very psychedelic effects such as time slowing down and extraordinary feats of instantaneous non-thinking coordination,” Oroc writes. “Athletes and normal individuals also claim the same effects in moments of heightened adrenaline – the classic fight or flight response.”

Over the coming years, as more robust research is performed on psychedelics, we will hopefully begin to get a clearer picture of the broad effects of these drugs. And as sport reaches even higher levels of precision, athletes will undoubtedly look for whatever advantage they can get – even if it potentially puts their health at risk in the process, as is often the case with many performance-enhancing drugs and extreme training regimes.

Arguments are already brewing over what constitutes an unfair advantage in sport. In the past it was relatively easy to draw the line at performance-enhancing drugs, but as technological advances thrust us into a transhumanist world of bionic implants and genomic editing it is becoming harder and harder to predict where professional sports is heading.

Elite athletes spend their lives training for such specific physical feats that their bodies are already somewhat unnaturally optimized. Are psychedelics, or other mind-manifesting pharmacological substances, the logical next step to help separate the best from the best of the best? What will the Olympics look like in 50 years?

*From the article here :
 
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Psychedelics as a performance-enhancer in athletics

by Shane O'Connor | Psychedelic Science Review | 8 May 2019

A look into the cognitive-enhancing effects of psychedelics in sports.

It’s a game of inches in the world of elite level, high stakes sports and many are willing to trade sportsmanship for glory. When the topic of Performance-Enhancing Drugs (PEDs) appears in the media, the discussion usually focuses on cases such as the state-sponsored doping program carried out by the Russian Olympic Committee, as depicted in the documentary Icarus, or the monumental fall from grace of former Tour de France “winner,” Lance Armstrong.

Erythropoietin (EPO) is probably the most well-known PED, due to its association with Lance Armstrong. EPO increases red blood cell (RBC) count in the body. Increasing RBC results in a higher rate of oxygen delivery from the lungs to the muscles, improving an athlete’s endurance and aerobic capacity (VO2 max). PEDs of past and present are formulated to give athletes an unfair psychical edge over their competitors; could PEDs of the future endow athletes with a cognitive advantage?

New perceptions

The terms psychedelics and PEDs are rarely associated with one another. In fact, for many years the conventional wisdom was that psychedelic usage “fries your brain,” thanks in part to public service campaigns aired in the eighties and nineties. However, recent studies into the benefits of microdosing suggest that the molecules may act as cognitive enhancers.

Microdosing is a process whereby individuals take psychedelics at doses lower than the threshold for a fully immersive psychedelic experience. These doses can be as low as 1/20th of a “normal” recreational dose. Thanks to the resurgence of interest and support for psychedelic research, academic institutions have begun to study the effects of microdosing. In a recent study conducted by the University of Leiden, researchers observed that microdosing psilocybin promoted cognitive flexibility, in turn increasing divergent and convergent thinking. How could this increase in cognitive flexibility endow an athlete with a competitive edge in sports?

Athlete’s anecdotes

In an article written for MAPS, athlete and author James Oroc discusses the prevalence of psychedelics usage at “psycholytic” doses among winter sports athletes. The term psycholytic dose refers to low, sub-threshold doses. Oroc is, in essence, describing microdosing. “Virtually all athletes who learn to use LSD at psycholytic dosages believe that the use of these compounds improves both their stamina and ability,” writes Oroc. Many athletes report improvements in balance, reflexes and concentration, along with the ability to overcome fatigue and altitude sickness. Interestingly, they liken the experience to being in a “flow-state” or being “in the zone.” Users report that time appears to slow down and that they become capable of “instantaneous feats of non-thinking coordination.”

Former Pittsburgh Pirate’s pitcher, Dock Ellis, claimed to have had experienced a psychedelic-induced flow state. On June 12th, 1970, Ellis threw a no-hitter against the San Diego Padres while under the influence of LSD. Ellis commented, “I can only remember bits and pieces of the game. I was psyched. I had a feeling of euphoria. I was zeroed in on the catcher’s glove.”

Another area of intrigue is the recent rise in popularity of marijuana usage in Brazilian Jiu-Jitsu (BJJ). While marijuana does not fall under the category of psychedelics, it is a psychotropic drug (a drug capable of affecting the mind, emotions, and behaviour). BJJ players report similar improvements in cognitive flexibility when they use marijuana before competing. BJJ is a highly cerebral martial art that focuses on grappling with particular emphasis on ground fighting. Practitioners and advocates of the sport often liken it to a game of chess rather than a street brawl. In an article written for BJJ world, journalist and BJJ practitioner Ognen Dzabirski writes, “Another thing weed and Jiu-Jitsu have in common is flow. Being high and rolling (sparring) are tightly related to the flow state. Weed helps your mind get into that “flow zone” where your rolls are seamless and just keep on going. It is Jiu-Jitsu at it’s finest and weed is a great way to find your flow.”

Regulatory questions

At present, psychedelics do not appear on the World Anti-Doping Agency’s (WADA) list of banned substances. The absence of psychedelics from the list presumably has to do with the lack of robust, scientific studies into their effects as PEDs. Interestingly, cannabinoids such as D9-tetrahydrocannabinol (the psychoactive constituent of the cannabis plant) are prohibited. According to the USADA, cannabinoids are viewed as a performance-enhancers since they can cause “muscle relaxation and reduce pain during post-workout recovery. It can also decrease anxiety and tension, resulting in better sports performance under pressure. Also, cannabis can increase focus and risk-taking behaviours, allowing athletes to forget bad falls or previous trauma in sport, and push themselves past those fears in competition.” This statement correlates with the anecdotal reports given by athletes on the performance-enhancing effects of psychedelics. One could postulate that if the athlete’s claims regarding the benefits of psychedelics are eventually verified by scientific studies, they may be viewed by doping agencies in the same light as cannabinoids.

Currently, WADA may grant a Therapeutic Use Exemption (TUE) to athletes using medical marijuana while competing. TUEs are decided on a case by case basis and are usually only given to athletes using medical marijuana to treat quite severe conditions, i.e. in those suffering from neuropathic pain. In recent years, there has been increased interest in research concerning the therapeutic effects of psychedelics in a multitude of affective disorders. It may be the case that athletes could apply for TUE while using psychedelics, should scientists elucidate the therapeutic benefits of these drugs.

Summary

A caveat to this article is that most, if not all, of the evidence provided, is anecdotal. Very little peer-reviewed, robust scientific literature exists on the topic of psychedelics as PEDs. The majority of discussion concerning this theme takes place on internet forums and message boards, such as Reddit. Understandably, the majority of research efforts are focused on the elucidation of the potential therapeutic benefits of psychedelics. While the Leiden University study mentioned at the beginning of this article has its limitations (i.e. absence of placebo group, the reliance on online questionnaires), it serves as a starting point for a more rigorous investigation into the subject matter. In the coming decades, the world may see a new breed of athlete, one who possesses a cognitive edge over their competition, thanks to mechanisms of action of psychedelics PEDs.

 
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WBA partners with Lobe Sciences for TBI and PTSD research

by Emily Jarvie | PSYCHEDELIC SPOTLIGHT | 4 Oct 2021

"We believe in the promise of the resurgence of psychedelic medicine and are proud to be collaborating with Lobe Sciences as we work together to improve the lives and health of members of the WBA family," says WBA president Gilberto Jesús Mendoza.​

Another boxing association has partnered with a psychedelics company to understand how psychedelic medicine can prevent injuries and optimize athlete performance.

The World Boxing Association (WBA) is working with Lobe Sciences, a Canadian life sciences company specializing in the development of alternative medicines for improved brain health, to build and launch a global registry for the identification and long-term management of current and former boxers with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD).

mTBI – also referred to as a concussion – is a usually non-life-threatening injury that occurs when a person’s brain cells are damaged temporarily from a bump, blow, or jolt to the head or a penetrating injury. A person can also experience a moderate or severe TBI, which can have life-long effects, such as the development of PTSD, or even cause death. Sadly, there are about 166 TBI-related deaths in the United States every day.

TBIs are common amongst boxers. According to the American Association of Neurological Surgeons, 90% of fighters will suffer a concussion at some point during their career, and approximately one in five professional boxers will experience chronic TBI.

The WBA, formerly known as the National Boxing Association, is the oldest of the four major sanctioning bodies in professional boxing, and it has committed to identifying and implementing more effective management and treatment of mTBI among its athletes. “It is no secret that a boxing match is highlighted by skillful defense and aggressive, sometimes violent, offensive attacks,” said WBA president Gilberto Jesús Mendoza.

“From the beginning, the WBA has known that a number of our members suffer from the short and long-term effects of varying degrees of mTBI associated with their time competing in the ring. We believe in the promise of the resurgence of psychedelic medicine and are proud to be collaborating with Lobe Sciences as we work together to improve the lives and health of members of the WBA family.”

Through this partnership, the WBA and Lobe Sciences also plan to develop a first-of-its-kind protocol to describe the best practices for the early diagnosis and treatment of brain injury to be used post-fight for current boxers. “For the boxers who have retired from active competition, we plan to take a more proactive approach and develop our own symptom tracking and mTBI identification tool to more accurately prioritize appropriate intervention, possibly with the therapeutic regimen being developed by Lobe Sciences,” Mendoza added.

In May 2021, the World Boxing Council became the first global sports governing body to study the impact of psychedelics on athletes. The council partnered with life sciences company Wesana Health on multi-year research which is investigating how psychedelics may be used to treat TBI. Wesana Health founder, former National Hockey League (NHL) player, and two-time Stanley Cup champion Daniel Carcillo, told the Psychedelic Spotlight podcast earlier this year that the company’s goal is to design, develop, and implement effective diagnostic tools for TBI that can be used on the field right away, starting with youth collision sports.

 
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Daniel Carcillo on Psychedelics for TBI

by Sarah Abelsohn | PSYCHEDELIC sPOTLIGHT | 18 Nov, 2021

During our time at Wonderland Miami, $PSYC CEO, David Flores, had the pleasure of sitting down with Wesana Health CEO, Daniel Carcillo, to talk about the significance of the conference and what it means to the arrival of the psychedelics industry. They also spent some time discussing Wesana’s collaboration with MAPS and the value that Mike Tyson is helping to create as a strategic partner to Wesana.​

In this episode, you’ll be able to learn more about:

– Wesana’s collaboration on MAPS
– Maps accelerating TBI much faster
– Mike Tyson partnership significance
– Removing psychedelics’ stigma and describing them as medicines,
– The most important psychedelic highlights of 2021

 
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Studying Ibogaine and 5-MeO-DMT for Traumatic Brain Injuries*

by Wesley Thoricatha | Psychedelic Times | 3 Jun 2021

Amber Capone is the co-founder and Executive Director of Veterans Exploring Treatment Solutions (VETS), where she and her husband Marcus Capone have led a charge to help special forces veterans connect with psychedelic treatments. Marcus is an ex-Navy SEAL who experienced traumatic brain injury during his time in the military, and was only able to find lasting healing with ibogaine and 5-MeO-DMT. Since then, Amber and Marcus have done their best to spread the word and raise money to help other veterans find effective treatments, and more recently, to encourage scientific study of these substances.

Amber, in our last interview you alluded to studies that your organization is involved in. Can you share some more details about that? Do these studies involve both ibogaine and 5-MeO-DMT?

Our first goal after Marcus’ therapy was for 12 other veterans to have a similar positive experience, and for those results to last for a 12 month period. That was easy. The second was to help 100 veterans and involve institutional review board (IRB) research. We did that and it was published in July of 2020.

The results were incredible. It was looking at suicidality, depression, substance use, and cognition. It was the first time, to my knowledge, that cognition was measured in a psychedelic study. Psychedelics have historically been researched for other psychological issues such as anxiety, depression, addiction, and so on, but the cognition piece was really significant to me. I insisted that it be included in the measures, because that was one of the biggest takeaways for me after Marcus’ treatment.

Traumatic brain injury (TBI) is the signature injury of both wars (Iraq and Afghanistan), yet it is not talked about that much because it can be very difficult to diagnose, let alone treat or cure. Generally veterans will get a bandaid PTSD diagnosis, and be prescribed a slew of medications. And in many cases, these medications compound the struggle and make things markedly more difficult for the veteran. Marcus at one point was on upwards of ten medications, and it seemed like as time went on, he would need a new medication to combat one of his existing medications, to combat the side effect of another medication, and so on. He was prescribed something to sleep, something to wake up, something for depression, something for mood- it was a nightmare. He was struggling cognitively to a point where he would forget to take these things, which could create a secondary nightmare because all the timing was off.

The TBI and brain component of veteran struggles is where our focus lies. We definitely believe that there are many veterans struggling with PTSD, and I’m not saying that special forces veterans don’t have PTSD, but we’re just choosing to put more of an emphasis on traumatic brain injury because this was so important for us and it remains largely unexplored. The retrospective study that was released showed a very significant improvement in cognition, and 96% of the participants said it was far better than any previous treatment they had tried.

Wow, that is a profound statistic. It must be so cool to see these things come to fruition after all your hard work.

It is, I was just talking to Marcus about this the other day, all the work and heart that goes into this. For every dollar that we take in there are scores of veterans fighting for it, and my heart breaks at the thought of having to say no to someone in need. It’s not a business, it’s a heart led effort, so it’s very difficult. I’ve given a lot of myself so that we can help more veterans, and I sometimes wonder how that can be more sustainable. We need to add organizational leverage and put the oxygen mask on the org a bit, but as exposure grows, so does demand. So we really need increased fundraising so that we can have more runway.

Absolutely. Are there any other studies that you have coming up?

Yes, so the first one we talked about was a retrospective study, and of course it’s not ideal to solely rely on that kind of research, so we are doing a prospective study of that same combo, ibogaine and 5-MeO-DMT. We expect that that study will be published sometime in late 2021.

We’re also kicking off a study partnership with Stanford University that is going to be looking at ibogaine for TBI. It will be the first ever study of its kind linking ibogaine to TBI in 30 participants, and the study will involve both FMRI scans of the brain as well as a series of other measures. This data will be collected before the treatment, immediately after treatment, and then a few weeks later. There’s a link to that study at clinicaltrials.gov.

We’re really excited to kick that off because it will have an emphasis on TBI and blast injury, in particular. Interface astroglial scarring and chronic traumatic encephalopathy (CTE) are the two phenomena frequently found in veteran’s brains, especially special forces, due to blasts and concussive and subconcussive events, which create microscopic injury and potentially degeneration in the brain. Ibogaine may potentially be useful for treating that. It is the only substance known to produce GDNF in the brain- Glial Derived Neurotrophic Factor- which promotes the growth of new glial cells. Who knows if clinical trials are in the future, but this is a very exciting first step.

*From the article here :
 
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Magic mushrooms ‘saved my life’

Former heavyweight champion calls psilocybin an "amazing medicine"

by Graeme Massie | The Independent | 28 May 2021

Mike Tyson says that magic mushrooms “saved my life” and now hopes psychedelics can change the world.

The former heavyweight champion of the world says that his personal and professional comeback is the result of taking mind-altering substances containing psilocybin as well as spiritual development.

“Everyone thought I was crazy, I bit this guy's ear off," Tyson told Reuters, referring to his 1997 fight against Evander Holyfield.

The Brooklyn-born fighter, who now is also a cannabis entrepreneur, says he has never felt better.

“It's scary to even say that,” he said,

“To think where I was - almost suicidal - to this now. Isn't life a trip, man? It's amazing medicine, and people don't look at it from that perspective.”

Tyson, who has partnered with life science company Wesana, founded by former NHL player Daniel Carcillo, says he believes in the positive benefits of psilocybin.

“I believe this is good for the world," added Tyson.

“If you put 10 people in a room that don't like each other and give them some psychedelics, they'll be taking pictures with each other."

"Put 10 people in a room who don't like each other and give them some liquor, and they'll be shooting everybody. That's real talk."

"(Wesana) was on the same level of thinking that I was. They wanted to share this with the world. This is very limited, us doing this in these small ceremonies."

"It needs to be open to the world.”

Medical experts studying psilocybin have warned against self-medicating or using them outside an approved medical framework, according to Reuters.

Wesana hopes to get psilocybin approved by the Food and Drug Administration for use in the treatment of traumatic brain injuries.

Tyson fought Roy Jones Jr in an exhibition fight in November, that ended in a draw, and is set to take on Lennox Lewis in September.

*from the article here :
 
endocannabinoids-running-neurosicecens-public.jpg

Exercise spurs the release of the body’s natural cannabinoids.

‘Runner’s High’ may result from Cannabinoids – The body’s own version of THC and CBD

New findings reveal exercise increases levels of endocannabinoids in the body. The findings may explain some of the beneficial effects of exercise on the brain and body.

by Hilary A. Marusak | Neuroscience News | 21 Dec 2021

Many people have experienced reductions in stress, pain and anxiety and sometimes even euphoria after exercise. What’s behind this so-called “runner’s high”? New research on the neuroscience of exercise may surprise you.

The “runner’s high” has long been attributed to endorphins. These are chemicals produced naturally in the body of humans and other animals after exercise and in response to pain or stress.

However, new research from my lab summarizes nearly two decades of work on this topic. We found that exercise reliably increases levels of the body’s endocannabinoids – which are molecules that work to maintain balance in the brain and body – a process called “homeostasis.” This natural chemical boost may better explain some of the beneficial effects of exercise on brain and body.

I am a neuroscientist at the Wayne State University School of Medicine. My lab studies brain development and mental health, as well as the role of the endocannabinoid system in stress regulation and anxiety disorders in children and adolescents.

This research has implications for everyone who exercises with the aim of reducing stress and should serve as a motivator for those who don’t regularly exercise.​

Health benefits of exercise

Several decades of research has shown that exercise is beneficial for physical health. These studies find a consistent link between varying amounts of physical activity and reduced risk of premature death and dozens of chronic health conditions, including diabetes, hypertension, cancer and heart disease.

More recently – over about the past two decades – mounting research shows that exercise is also highly beneficial for mental health. In fact, regular exercise is associated with lower symptoms of anxiety, depression, Parkinson’s disease and other common mental health or neurological problems. Consistent exercise is also linked to better cognitive performance, improved mood, lower stress and higher self-esteem.

It is not yet clear what is behind these mental health boosts. We do know that exercise has a variety of effects on the brain, including raising metabolism and blood flow, promoting the formation of new brain cells – a process called neurogenesis – and increasing the release of several chemicals in the brain.

Some of these chemicals are called neurotrophic factors, such as brain-derived neurotrophic factor. BDNF is intricately involved in brain “plasticity,” or changes in activity of brain cells, including those related to learning and memory.



Scientists have also shown that exercise increases blood levels of endorphins, one of the body’s natural opioids. Opioids are chemicals that work in the brain and have a variety of effects, including helping to relieve pain. Some early research in the 1980s contributed to the long-standing popular belief that this endorphin release is related to the euphoric feeling known as the runner’s high.

However, scientists have long questioned the role of endorphins in the runner’s high sensation, in part because endorphins cannot cross into the brain through the blood-brain barrier, which protects the brain from toxins and pathogens. So endorphins are not likely to be the main driver for the beneficial effects of exercise on mood and mental state.

This is where our research and that of others points to the role of our body’s natural versions of cannabinoids, called endocannabinoids.​

The surprising role of endocannabinoids

You may be familiar with cannabinoids such as tetrahydrocannabinol – better known as THC – the psychoactive compound in cannabis (from the Cannabis sativa L. plant) that causes people to feel high. Or you may have heard of cannabidiol, commonly known as CBD, an extract of cannabis that is infused in some foods, medicines, oils and many other products.

But many people do not realize that humans also create their own versions of these chemicals, called endocannabinoids. These are tiny molecules made of lipids – or fats – that circulate in the brain and body; “endo” refers to those produced in the body rather than from a plant or in a lab.

Endocannabinoids work on cannabinoid receptors throughout the brain and body. They cause a variety of effects, including pain relief, reduction of anxiety and stress and enhanced learning and memory. They also affect hunger, inflammation and immune functioning. Endocannabinoid levels can be influenced by food, time of day, exercise, obesity, injury, inflammation and stress.

It’s worth noting that one should not be tempted to forgo a run or bike ride and resort to smoking or ingesting cannabis instead. Endocannabinoids lack the unwanted effects that come with getting high, such as mental impairment.​

Understanding the runner’s high

Studies in humans and in animal models are pointing to endocannabinoids – not endorphins – as the star players in the runner’s high.

These elegant studies demonstrate that when opioid receptors are blocked – in one example by a drug called naltrexone – people still experienced euphoria and reduced pain and anxiety after exercise. On the flip side, the studies showed that blocking the effects of cannabinoid receptors reduced the beneficial effects of exercise on euphoria, pain and anxiety.

While several studies have shown that exercise increases the levels of endocannabinoids circulating in the blood, some have reported inconsistent findings, or that different endocannabinoids produce varying effects. We also don’t know yet if all types of exercise, such as cycling, running or resistance exercise like weightlifting, produce similar results. And it is an open question whether people with and without preexisting health conditions like depression, PTSD or fibromyalgia experience the same endocannabinoid boosts.

To address these questions, an undergraduate student in my lab, Shreya Desai, led a systematic review and meta-analysis of 33 published studies on the impact of exercise on endocannabinoid levels. We compared the effects of an “acute” exercise session – like going for a 30-minute run or cycle – with the effects of “chronic” programs, such as a 10-week running or weightlifting program. We separated them out because different levels and patterns of exertion could have very distinct effects on endocannabinoid responses.

We found that acute exercise consistently boosted endocannabinoid levels across studies. The effects were most consistent for a chemical messenger known as anandamide – the so-called “bliss” molecule, which was named, in part, for its positive effects on mood.

Interestingly, we observed this exercise-related boost in endocannabinoids across different types of exercise, including running, swimming and weightlifting, and across individuals with and without preexisting health conditions.

Although only a few studies looked at intensity and duration of exercise, it appears that moderate levels of exercise intensity – such as cycling or running – are more effective than lower-intensity exercise – like walking at slow speeds or low incline – when it comes to raising endocannabinoid levels. This suggests that it is important to keep your heart rate elevated – that is, between about 70% and 80% of age-adjusted maximum heart rate – for at least 30 minutes to reap the full benefits.

There are still a lot of questions about the links between endocannabinoids and beneficial effects from exercise. For example, we didn’t see consistent effects for how a chronic exercise regimen, such as a six-week cycling program, might affect resting endocannabinoid levels. Likewise, it isn’t yet clear what the minimum amount of exercise is to get a boost in endocannabinoids, and how long these compounds remain elevated after acute exercise.

Despite these open questions, these findings bring researchers one step closer to understanding how exercise benefits brain and body. And they offer an important motivator for making time for exercise during the rush of the holidays.

Funding: Dr. Marusak is funded, in part, by the National Institutes of Mental Health (K01MH119241).

About this exercise and mental health research news

Author:
Hilary A. Marusak
Source: The Conversation
Contact: Hilary A. Marusak – The Conversation

 
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