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Speed as an antidepressant?

Dante

Dante

Bluelight Crew
Joined
Oct 30, 2001
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Was wondering what other people thought of this... My first pill experience was a speed bomb (as it is for so many people), and I found that the day after, I was walking from the hotel we stayed in, and just looking around, felt as if I was viewing everything afresh, as if all my preconceptions of the world had disappeared, and that the world wasn't that bad a place after all.
Now, considering that only a week or so before, I had been incredibly depressed, and now I was content, I've had the view that whatever was in that pill (possibly some MDMA as well as speed) acted as an antidepressant.
However, recently, I had a dose of speed, and noticed that it had antidepressant effects, in comparison to MDMA, which may only last a few hours/days...
Any takers on the subject? It's something I'd like to look into more.
And admin, sorry if this is the wrong place to be posting, but I figured it is a discussion of drugs.
 
Well from experience i find drugs are different with everyone, but i take whizz every weekend (occassionally the odd pill) and i've never found speed to act as an anti depressant, if anything it's the worst drug i come down from (well worth it) but i'm a wreck by Mon/Tues on a very emotionally downhill slide. Even if i have speedy local pills, it does the same thing. :(
 
Here's my take.. I will try to make it as relavant as possible but I do get sidetracked sometimes ..
As far as I am concerned your mind on it's own is an antidepressant on the flip side it also can create depression.
In relation to whether speed is an antidepressant that all depends on your take on it, if you take "speed" (or mdma, legal drugs etc) with the expectation that for the days following it your happiness with increase then it's highly likely that you will find that your happy and see the world in a desirable way however if you beleive that speed leaves you with an almighty comedown then you may notice the world sucks around you.
I dont come down (very often at all) because I dont let myself. When my mind starts to wander to negative thought patterns I remove myself from the situation that is creating it.
If the first time you have "speed" your view/emotions following was desirable (which may have been caused by many contributing factors) then next time you have some your mind already expects to have that result again, so thats what you see. And then the following time it happens again becuase it did the first two times so why not this time again.. Unless there is a great change in those contributing factors (large mind/mood altering charge in your life recently) you will continue to believe that it does in fact have a anti depressant effect on yourself which will result in it having that exact effect.
I could write pages on this to better make my point eventually I wouldnt stay on topic so I will save everyone the bordom..
Its all about Mind over Matter... We control our own minds, whether we relise it or have learnt how to control it to better our lives we do create the moods and emotions we feel.
 
I used to take speed regularly (every day) about 5 years ago, and it was the most fucked up thing I've ever done. I still take it occasionally, but I would say it's as far from an antidepressant as they come. Sure it makes you feel good.... it makes you feel fantastic!! Attitude plus... talk to everyone.... but the come down was more depressing than anything i've ever known. When coming down, I get so depressed so quickly, the slightest thing can set me bursting into tears. That's why it's so easy to get addicted to the stuff.... makes you feel great, till you come down. Solution? Take more!!! Pretty depressing on your wallet too!
 
I so am readin you hey, that's where i am at the moment with whizz, not everyday, every weekend and it's fuckin with my emotional status bigtime. The weight loss is great and the high is wonderful, but the comedown sucks ass :(
 
Dont fool yourself...cast your mind (as painful as it maybe!) back to your high school science lessons...
"What goes up MUST come down"
The best antidepressants are sleep, a good diet, avoiding stress and decent caring friends/family!
 
Didn't find anything really conclusive, but do a search for 'amphetamine antidepressant' in google and you'll find some interesting reading...
I agree in part with dancinbabe, set and setting (including your mindset) play a big part in the way drugs will affect you, both before, during, and after taking them... Not just amphetamines but all drugs...
The first time I took acid I flipped out bad, and since then, any drug with psychadelic properties, even nitrous can easily freak me out...
I know someone who has a similar bad reaction to mdma, prolly 'cos of one really bad experience he went through, from what I remember was very similar to one of my bad trips...
So it is quite possible to convince yourself that whatever drug you take will have a specific effect, even it its not the standard effect... The placebo effect can be quite powerful...
As far as actual effects at a chemical level, perhaps reduced amounts of dopamine after the speed wears off leads to serotonin more effectively binding to serotonin receptors since there isn't so much dopamine floating around in there anymore... I just pulled that outta my ass btw, I've got no idea if it has any basis in fact...
[ 13 December 2001: Message edited by: Tarsarlan ]
 
Amphetamines have been used as anti-depressants in the past. Sure, taken acutely they lift your mood, but they are also neurotoxic. Also they have other side-effects that can be severe with chronic use (like weight loss, insomnia, increased BP and heart rate etc). Here is a recent report from Medscape on damage to one type of dopamine receptor caused by methamphetamine.
Dysregulation of Orbitofrontal Cortex Linked With Methamphetamine Abuse
--------------------------------------------------------------------------------
WESTPORT, CT (Reuters Health) Dec 03 - Methamphetamine abuse causes a decline in dopamine D2 receptor levels, according to a report in the American Journal of Psychiatry for December. These decreased levels are associated with dysregulation of the orbitofrontal cortex, which may cause the drug craving that addicts experience, researchers say.
Dr. Nora D. Volkow, of Brookhaven National Laboratory in Upton, New York, and colleagues compared positron emission tomography (PET) scan results for 15 methamphetamine abusers and 20 non-drug-abusing control subjects.
Estimates of dopamine D2 receptor availability were significantly lower in the caudate and in the putamen of the drug abusers than in the control subjects. The D2 receptor availability in the putamen was significantly correlated with metabolism in the orbitofrontal cortex in the drug abusers but not in the control subjects.
"The orbitofrontal cortex is the area of the brain that modulates the relative value of one reinforcer over another," Dr. Volkow noted in an interview with Reuters Health. "So, for example, what makes a monkey choose an apple over a piece of lettuce is that the apple generates more pleasure, which is modulated by dopamine."
For methamphetamine abusers with low levels of D2 receptors and orbitofrontal cortex dysregulation, she continued, the dopamine signals are blunted and "normal things like food, sex, intellectual curiosity, or art are no longer strong enough to induce a pleasure response."
Treatment strategies need to increase the value of other reinforcers that can compete with methamphetamine, Dr. Volkow said. This is why support groups, which can promote active feelings of well being, are frequently used as therapy, she added.
Medications that increase dopamine levels, such as selective serotonin reuptake inhibitors, have been disappointing, she noted. However, "I think we are asking too much of the drug, that is, to totally stop the desire to use methamphetamines."
Instead, she said, "we need to ask if the drug can decrease the craving in certain circumstances."
Am J Psychiatry 2001;158:2015-2021.
Just to clarify the bit there about SSRI's increasing dopamine, because that probably sounds wrong. Normally, serotonin has an inhibitory effect on dopamine release, so more serotonin=less dopamine. Initial use of an SSRI causes an increase in serotonin, but eventually this increase leads to receptor down-regulation, and lowered serotonin levels. This would decrease the inhibitory effects of serotonin=increased dopamine release.(Just in case anyone cared!)
 
Speed is a stupid, nasty, dirty, horrible drug.
Now someone please rack me up another line ;)
Seriously, use speed as a tool, to give you more energy, to dance like a madman or to get through work the next day. Relying on speed for a mood lift is a sure fire path to trouble.
 
I find the replies in this thread most interesting, in my personal experience I have found stimulants to have been most helpful.
I used to suffer greatly from depression, for a long time, years in fact, it was not your run of the mill daily blues kind of depression, but the full blown wish I was dead kind,clinical depression.
I had been prescribed various kinds of anti - depressants by different doctors, with absolutely no good effects whatsoever - in fact some of them made it worse.
Then in my travels I happened to come across meth/ice etc - in a nutshell they have changed my life.I am now happy all the time, and dont worry about trivial insignificant things.
And no, I'm not tweeked outta my skull, I can hear you saying he's fucked up all the time, I partake maybe once a fortnight or maybe once a week when I'm really out raging.Its changed my perspective on things and life, and it suits me perfectly.I also have no problems when I'm coming down, and consider it to be quite tolerable.
I realise this is probably not the norm, and that to some its probably very harmful.
In summary all I can say is I wish I had discovered it a lot earlier in my life, a lot of years would not have been needlessly wasted on that scourge of my life - depression.
 
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