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Some Neat MDMA Facts

AylaV

AylaV

Bluelighter
Joined
Dec 6, 2007
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Basalt, ID
I'll throw this onto the MDMA FAQ at some point most likely, but I found this awesome article written a little over a year ago that examines MDMA in a much less hostile environment and uses MRIs to try to study something other than "holes" in your brain ;) Check it out (I feel this is more MDMA related than "new" related which is why it's not in that forum) --

http://sciencelife.uchospitals.edu/...the-neurobiology-of-social-behavior/#more-746

Among highlights..

Feelings of empathy and sociability are also difficult concepts to measure in animals, where most drug research is still performed for legal and ethical reasons. How do you determine whether MDMA makes a rat “friendlier” with other rats? One method, employed in a 2005 study, measured the likelihood of rats to lie next to each other, sort of a cuddle test. Sure enough, a dose of MDMA increased the likelihood that rats who had not previously met would lie next to each other.
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Researchers then guided the subjects to an MRI machine, where images were taken of their brains as they viewed a picture set of people making different facial expressions. Those under the influence of MDMA showed both a heightened response to happy faces and a dampened response to angry faces. A brain region called the ventral striatum, which is associated with reward processing, showed stronger activation to happy versus neutral faces in subjects given MDMA, the authors found. Conversely, when angry faces were showing, the response of the amygdala, a region involved in the processing of negative emotions was reduced, suggesting a lower sensitivity to social threat.
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I especially like this second quote. Next time someone said MRIs show that MDMA puts holes in your brain, you can say "although MDxx most certainly has negative effects on the brain, MRIs have shown that MDMA makes happiness hyper-rewarding and negates the hyper-importance of fear and anger produced by the amygdala."

The main plus of that is making your friends feel stupid for telling you MDMA puts holes in your brain. =D I dunno.. just thought that was super cool and wanted to share it with you all.
 
Seems like it's nothing new, but now there's a scientific study behind it for once.
 
its always a good laugh when someone that watches too much t.v start carrying on about the holes in the brain shitee. had someone telling me that mdma stays in ur saliva forever the other day and id never be able to drive again ( random driver drug tests) soon told them... can last a while i hear tho....
 
It's kinda of funny too see academics trying to figure out the effect profile of MDMA, when most ravers already know what it does. Not saying this kind of stuff shouldn't formalized via a methodological approach, I just think it's funny to read about it in formal academic articles.

I mean any raver/EDM fan know perfectly well what exactly MDMA does to you. Sure not everyone is going to use words like empathogenesis and entactogenesis, but everyone understands the core idea behind it. It's awesome to see people happy on MDMA, it's awesome to be happy on MDMA. You feel connected and close to the people around you. You open up and are willing to share quite personal issues with confident ease.

"“There is only so much you can glean about social experiences from an animal,” Bedi said via e-mail from Australia. “I think it is a fascinating drug in terms of its effects on social behavior and function, in particular given that these social effects appear to be a fundamental part of the reinforcing effects of the drug. So, in this way ecstasy gives us a window into a broader issue, which is how drug effects and social factors interact at a more biological level, and whether such interactions are an important part of why people use drugs.”
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I don't about you guys, I definitely know that social interaction is a fundamental part of taking MDMA. I've always enjoyed it way more when I am doing it with other people who are also rolling. When only half your crew (or less) are rolling it really changes the dynamics of the experience.

Interesting article, nonetheless.
 
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It's a truly amazing compound. There are so many articles that go on about how MDMA is mix between a psychedelic and a stimulant and fail to realise that there is a word for drugs like MDMA (empathogen, or later coined by nichols, entactogen). I think if people understood that MDMA and its sister chemicals were about being put in the best emotional state possible, it would be less demonised. Entactogens are about bringing out the most constructively positive aspects of the human animal.

It's odd that drugs, like alcohol, not to rat on it, mind you, are legal that bring out the carnal, animal nature of humans are legal -- yet somehow it's bad to take a drug that brings out the best the human animal can offer.

Just my opinion, though ;)
 
Great post but the problem I see with it is that MDXX compounds have a high potential for abuse. I know, I've gone on massive benders with it and if I didn't have my 5-HTP to recover probably would have killed myself afterwards. The bottom line is that while they are wonderful drugs, I think their downsides outweigh the positives.
 
I'm nor sure if I agree with the above post about abuse potential.
That was your experience, whether it was widespread is another matter.
My own experience is that after abusing mdma for a while I was increasingly disinclined to it until I abstained for 6 months.
 
the potential of abuse is in the hands of the roller,
i love mdma, i definately could abuse the drug and cause very permanent damage, but i choose not too. i repect it. and learnt the power of it and have kept that power alive by respecting it.
i love mdma, the excitement it gives me can make me dry reach.
@ aylav.
i couldnt agree more about the alcoholl statement, would love to see these animalistic government do gooders on a neat 150mg dose of mdma
 
The problem is that the vast majority of ecstasy users DO abuse the shit out of it - they're not aware of the consequences until its too late. So yes, MDXX are drugs of abuse. But its due to a lack of harm reduction information, not due to the drug itself.
 
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