I went to an all-girls school, so things could get pretty bitchy as you can imagine, but being me, I chose to ignore the politics. I had a core group of about 8 girls that I hung with alll the time. Now I'm lucky if I see them at all.
The transition from school to uni (2000) wasn't that hard, but since I'm doing a different course to my friends, I don't see them at all. We've all got different timetables or go to different unis, and we've all made new friends. I still get invited to parties, but they all seem to be stuck in high school, reminiscing about the same things every time (teachers, bitches and boyfriends). I can't stand it because I've changed so much.
I've got friends who don't use drugs that I hang out with, but I just find it hard to have a really close friendship with any of them, because I find what they talk about to be so boring and ordinary I want to cry. It's nothing against them personally.
So, yes, I'm saying most of my close friends I have made in the last 2 years use, and most are bluelighters or those I've met in the scene. Not all pill or use speed, some are just stoners that I chill with. But most do both.
Maybe it's just me, and I know that before I leave uni I'll change a lot more than I have in the past couple of years. I know that I need other people to "ground" me, but I totally agree with Jakoz. The people I'm closest to use, and I don't really care that they've seen me at my worst, because I've seen them too.
That's my $0.02 anyway.