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Stimulants Smoking meth + blood pressure medication, Bad Mix?

Tyrielle

Bluelighter
Joined
Nov 9, 2012
Messages
77
Hey guys just wondering if anyone knows if it would be a bad idea to take my blood pressure medication (Deralin/propanolol 10mg) while still fairly buzzin after a night out on the toke. I take the medication normally once every couple days, i was initially prescribed it because i used to smoke meth a lot more regularly and under much more stressful times. Since then I've quit ciggarettes and pretty much in better form.

I just wanna take it to stop my heart racing so much I'm getting anxious about it but not feeling any pain, cheers in advance.
 
Thanks for the reply Jay,

So best thing would be just to wait it out? Do you reckon a few beers would help calm it down?
 
Have a benzo, it's probably the best solution.

Alcohol works for me yea, just don't drink too much and get extremely drunk when the effects wear off.
 
"Hypertension, tachycardia, and vasospasm can be managed with an alpha blocker such as phentolamine or a nitrate such as nitroglycerin or nitroprusside. Nitroprusside may be more effective than nitroglycerin in this setting. Beta blockers should be avoided because they can result in unopposed alpha-receptor stimulation, which would further increase heart rate and exacerbate vasospasm, hypertension, and cardiac ischemia." - from another website discussing methamphetamine OD, so the answer again is no.
 
Sunk a few beers and heart rate seems to have steadied.. feeling the onset of coming down already tho haha.

Thanks for elaboration RTrain
 
If you can't get your hand on Alpha-Blockers, then perhaps you might consider:

Aspirin Low Dose - It'll thin your blood, which is a preventative measure for those with hypertension, tachycardia, etc. to protect against the formation of blood clots, which, worst case scenario can cause a stroke.

Coenzyme Q10 - Apparently, this antioxidant can also lower blood pressure modestly, and it has a blood thinning effect to boot. In fact, it's contraindicated in patients who are on blood pressure and blood thinning meds.

Xanax - The only reason why I list this benzodiazepine by brand name (rather than all benzos) is because, according to a study by Coronary researcher John D. Folts and his co-workers at the University of Wisconsin-Madison, adding alprazolam (Xanax) to a low dose acetylsalicylic acid (Aspirin) preventative therapy regimen could prevent arterial blood clots that lead to heart attacks.

In 1978, Folts and his co-workers at the University of Wisconsin-Madison, discovered that giving aspirin to dogs with narrowed coronary arteries did not prevent heart attacks if the dogs also had high blood levels of the hormone epinephrine. He found that epinephrine contributed to heart attack risk by promoting the aggregation of platelets, the blood cells that drive clotting.

Aspirin helps prevent blood clotting by binding to a specific receptor on the platelet surface. But it does nothing to reduce anxiety-driven heart attacks, because epinephrine -- the "fight-or-flight" hormone associated with anxiety -- does not act on platelets through the same receptor, Folts explains.

His team has now tested alprazolam and 10 dogs treated with aspirin for several days and then given an infusion of epinephrine. Only one dog developed clotting in the coronary arteries (coronary thrombosis), Folts reports. But when the same dogs received only aspirin before the epinephrine infusion, seven of the 10 developed the heart-threatening blood clots. Similarly, dogs given only alprazolam alone showed no reduction in coronary thrombosis.

Aspirin plus alprozolam "apparently shows complete protection" from heart-attack-causing blood clots, Folts asserts. Alprazolam's protective effect does not result solely from its mood-calming capacilities, he maintains, citing studies at the University of Texas Southern Medical Center in Dallas, in which aspirin combined with the sedative diazepam (Valium) did not ward off coronary thrombosis in patients recovering from heart attacks. Folts suggests that alprazolam acts by blocking platelet-activating factor, a clot-inducing protein produced by cells lining the blood vessels.


Source - http://www.thefreelibrary.com/Anti-anxiety+drug+may+help+nix+heart+attacks.-a010808891

I have been using a combination of Xanax + Aspirin Low Dose for about 4 and 1/2 years now, and while I cannot prove beyond a reasonable doubt that it works, indeed it did seem to help me considerably (alleviated pounding/racing heart sensations as well as any anxiety/panic), particularly when using potent stimulants, such as blow, dextroamphetamine, etc.
 
10mg is like almost no propranolol. It will make absolutely no difference. High doses of beta-blockers and amphetamines are contraindicated, but this isn't. I'm not even sure exactly why you are on 10mg... that's a very low dose even for performance anxiety. The issue with adrenergic storm would only come in at fairly insane doses of both meth and propranolol.

Phenoxybenzamine (alpha 1+2 blocker) works well for treating more serious stim induced hypertension combined with clonidine (alpha 2 agonist), as clonidine is has more affinity to the alpha 2 receptor than phenoxybenzamine. I suppose you could throw beta blockers on top of that in theory, if you really don't like having any blood pressure. Really it is all about the dosing... 100mcg of clonidine alone is usually enough to eliminate any hypertension from 30mg doses of meth.
 
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I apologize for somewhat hijacking the thread, but I'm wondering if mixing potent stimulants with appropriate/non-contraindicated hypertension medication (such as clonidine) would put more stress on the cardiovascular system (particularly the heart) than the stimulant alone?
 
Dude take a Alpha blocker Selective Alpha 1 Blocker. Such as Prazosin and medication in this class. Do not Take Phentolamine or Phenoxybenzamine. Because Phenoxybenzamine blocks presynaptic Alpha 2 Receptors on the heart leading to Reflex Tachycardia. Your Heart rate will shoot through the roof. Prazosin, Clonidine and a Benzodiazepine are good.
 
I'm fairly sure both phenoxybenzamine and phentolamine have less binding affinity for the alpha 2 receptor than clonidine, and as a result will basically behave as selective alpha 1 blockers if co-administered with clonidine.
 
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