Deru, do you know if these forms of neuropathy that seem clearly associated with drug use will eventually lead to things like autonomic neuropathy - the form of neuropathy that Johnny Cash?
A friend and fellow lightweight competitive strongman of mine was drinking FOUR Monster Energy drink per day, and after a few months of doing this, ended up getting numbness all throughout his left leg. I think in time, things got better, but it shocked me what an over-the-counter drug could do when done 4x the daily limit [because I think I am not the only BlueLighter to have gone over 4x the daily limit of our drug of choice - in my case: opiates!].
I definitely get a little myoclonus when I do opiates. That, in itself, is not a huge concern. I used to go to sleep using Xanax to attempt to sleep through withdrawal of opiates, and find myself waking up in the middle of the night with sleep paralysis. I think my body wanted to wake me up to re-dose the opiates, but the Xanax wanted to keep me asleep; hence the sleep paralysis. Now THAT made me much more concerned about damage to my central nervous than the myoclonus - which is something I have had to some extent my entire life [as is true of many of us - myoclonus is quite normal...sleep paralysis is normal too, but not at the frequency I was getting it at when combining opiates and benzodiazepines, which leads me to believe it was absolutely my drug use which caused it].
Also, sort of on-topic, sort of not: does anyone here do tests to see if they have damaged their CNS? I often try to hold my hands in front of me, and look for even the slightest shaking of my fingers. If I see nothing, I consider that to be a good sign.