MyDoorsAreOpen
Bluelight Crew
- Joined
- Aug 20, 2003
- Messages
- 8,542
tl;dr version: I've just done a good bit of homework on selegeline, and am pretty sure my life has a useful place for it. Convince me not to, if you see a good reason.
Ah, amphetamine...
I never thought I'd fall for this siren song again. No, actually I'm not that shocked I did. Or maybe this drug's mythological or archetypal counterpart is the smooth-talking devil, who just shows up when you're alone, every so often, telling you new sweet lies about why you should (re)join his side.
I started school again, the portion that's on-the-job training, and had somehow convinced myself doing 10mg of adderall every day (but this time with no DXM, ever), would suit me well. It's questionable whether the drug has done a lot for me, but the bottom line is, tolerance and side effects made me quit it after about 5 weeks of daily use of between 10 and 25 mg. I really can't see how many people with ADD stay on this for years. It DID take away my ADD. But it's just unsustainable as a long term frequent use drug!
I've just had a shitty 3 day comedown, which a 2nd plateau DXM powder trip helped alleviate, but didn't eliminate completely.
Selegeline, by contrast, looks a lot more tolerable in small doses over long periods of time. I'm just kind of sick of feeling blunted and humorless most of the time. I want to be as joyful and outgoing and FOCUSED a worker I was when I first (re)started adderall, because that's what school demands.
I don't plan on mixing amphetamine and selegeline. But caffeine I'm not intent on quitting. I'd probably quit selegeline at least a week if I planned on using MDMA, which isn't very often.
Something I find really interesting about antidepressants is that the older and the blunter tools they are, the better efficacy they have. Nardil was a crude drug with a lot of side effects, but it DID get rid of depression. TCAs were pretty good too. Selegeline is kind of like an old school antidepressant -- it's an MAOI. But selective.
Is dopamine receptor downregulation mediated tolerance a big issue with selegeline?
My interest in this drug is purely practical, not recreational.
Ah, amphetamine...
I never thought I'd fall for this siren song again. No, actually I'm not that shocked I did. Or maybe this drug's mythological or archetypal counterpart is the smooth-talking devil, who just shows up when you're alone, every so often, telling you new sweet lies about why you should (re)join his side.
I started school again, the portion that's on-the-job training, and had somehow convinced myself doing 10mg of adderall every day (but this time with no DXM, ever), would suit me well. It's questionable whether the drug has done a lot for me, but the bottom line is, tolerance and side effects made me quit it after about 5 weeks of daily use of between 10 and 25 mg. I really can't see how many people with ADD stay on this for years. It DID take away my ADD. But it's just unsustainable as a long term frequent use drug!
I've just had a shitty 3 day comedown, which a 2nd plateau DXM powder trip helped alleviate, but didn't eliminate completely.
Selegeline, by contrast, looks a lot more tolerable in small doses over long periods of time. I'm just kind of sick of feeling blunted and humorless most of the time. I want to be as joyful and outgoing and FOCUSED a worker I was when I first (re)started adderall, because that's what school demands.
I don't plan on mixing amphetamine and selegeline. But caffeine I'm not intent on quitting. I'd probably quit selegeline at least a week if I planned on using MDMA, which isn't very often.
Something I find really interesting about antidepressants is that the older and the blunter tools they are, the better efficacy they have. Nardil was a crude drug with a lot of side effects, but it DID get rid of depression. TCAs were pretty good too. Selegeline is kind of like an old school antidepressant -- it's an MAOI. But selective.
Is dopamine receptor downregulation mediated tolerance a big issue with selegeline?
My interest in this drug is purely practical, not recreational.
