Salvia coccinea - ingredients and uses.

[izo]

Salvia coccinea - Wikipedia

en.wikipedia.org

from this one there are no mentionings of any psychoactive effect from rätsch or wikipedia.

there is this short resmue which is kinda amusing:

a psychoactive effect.

 

[izo]

a somewhat not relevant paper about its antioxidant activity is available:

2018 - Changes in Photosynthetic Pigments, Total Phenolic Content, and Antioxidant Activity of Salvia coccinea Buc’hoz Ex Etl. Induced by Exogenous Salicylic Acid and Soil Salinity

Abstract: Salvia coccinea (Lamiaceae) is a promising source of potential antioxidants, and its extracts
can be used in pharmaceutical industry, as well as in food products and cosmetics. Salicylic acid (SA)
affects many physiological and metabolic processes in vascular plants under salinity stress. The aim
of this study was to investigate the response of S. coccinea to either SA, or sodium chloride (NaCl),
or a combination of both. The plants were sprayed with a solution of 0.5 or 1.0 mM SA and watered
with 0, 100, 200, or 300 mM NaCl. Exogenous application of SA increased the number of branches,
fresh herbal weight, and total chlorophyll content vs control plants. Salinity-exposed plants showed
reduced growth, content of photosynthetic pigments total polyphenols, and antioxidant activity.
However, foliar application of SA relieved the adverse effects of 100 mM NaCl, as demonstrated by
increased number of branches, greater fresh herbal weight, higher content of total chlorophyll, total
carotenoids, and total polyphenols, as well as antioxidant potential, detected using ferric-reducing
ability of plasma (FRAP) and 2.20-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt
(ABTS), compared with untreated plants.

 

[izo]

also not really informative. gonna give a freedback about the usual 100:1x extract when tested.

2021 - Inhibitory effect of Salvia coccinea on inflammatory responses through NF-κB signaling pathways in THP-1 cells and acute rat diabetes mellitus

A B S T R A C T
Hyperglycemia-induced oxidative stress has been implicated in diabetes and its complications. Medicinal plants
possessing antioxidant activity may decrease oxidative stress by scavenging radicals and reducing power activity
and would be a promising strategy for the treatment of inflammatory disorders like diabetes. This study was
designed to evaluate the antioxidant effect of Aqueous Extract of S.coccinea leaf (AESL) in HG treated THP-1 cells
and streptozotocin (STZ)-induced diabetic Wistar rats. AESL and the standard antidiabetic drug glibenclamide
were administered orally by intragastric tube for 14 days and pre-treated HG grown THP-1 cells. AESL treatment
reduced HG induced increase in ROS production, NF-κB dependent proinflammatory gene expression by influencing
NF-κB nuclear translocation in THP-1 cells. Oral administration of AESL inhibited STZ-induced increase in
serum lipid peroxidation, aspartate transaminase, alanine transaminase, and Lactate dehydrogenase of diabetic
rats. Significant increase in activity of superoxide dismutase, catalase and glutathione peroxidase, and a reduced
level of glutathione, were observed in AESL treatment. The results demonstrate that AESL is useful in controlling
blood glucose and also has antioxidant potential to influence the translocation of NF-κB, protect damage caused
by hyperglycemia-induced inflammation.

 

[izo]

taste of the extract is the first that is someting different. most slightly bitter, some like nothing, some sweet or tasteless. nasal consumption of these extracts were also possible and even will show improved activity.

ok same with this extract. still waiting for some effect from the oral admin. but im on hhc and had a definitive short kind of rush from nasal administration. went away somewhat fast.

 

[izo]

2019 - Chemical Composition and antibacterial activity of the steam volatile extract from Salvia coccinea Juss. ex Murr

Abstract: The essential oil of Salvia coccianea. Juss. ex Murr. (Lamiaceae) was analyzed by capillary GC and GC/MS. Total 60 components were identified constituting 91.1 % of the oil. The oil was found rich in oxygenated sesquiterpene hydrocarbons (32.6%). Germacrene D (15.6%), linalool (10.7%), β -caryophyllene (8.2%) and palmitic acid (8.9%) were the principal constituents. The oil showed good activity exhibiting the minimum bactericidal effect against Klebsiella pneumoniae at 125 μL/mL and against Bacillus subtilis at 250 μL/mL concentration. The oil showed quite significant antibacterial activity against Escherichia coli, S. aureus, B. subtilis which was found comparable with the standard antibiotics used for comparison.

ok finally some compounds named that are in there:

Linalool - Wikipedia

en.wikipedia.org

Germacrene - Wikipedia

en.wikipedia.org

Caryophyllene - Wikipedia

en.wikipedia.org

Palmitic acid - Wikipedia

en.wikipedia.org

 

[izo]

Caryophyllene - Wikipedia

en.wikipedia.org

β-Caryophyllene acts as a full agonist of the Cannabinoid receptor type 2 (CB2 receptor) in rats.[6] β-Caryophyllene has a binding affinity of Ki = 155nM at the CB2 receptors in mice.[7] β-Caryophyllene has been shown to have anti-inflammatory action linked to its CB2 receptor activity in a study comparing the pain killing effects in mice with and without CB2 receptors with the group of mice without CB2 receptors seeing little benefit compared to the mice with functional CB2 receptors.[6] β-Caryophyllene has the highest cannabinoid activity compared to the ring opened isomer α-caryophyllene which may modulate CB2 activity.[8] To compare binding, Cannabinol (CBN) binds to the CB2 receptors as a partial agonist with an affinity of CB2 Ki = 126.4 nM[9] while Delta-9-Tetrahydrocannabinol binds to the CB2 receptors as a partial agonist with an affinity of Ki = 36nM.[10]

seems i found why it is sold. although as a simple hydrocarbene this shouldnt be active via nasal application as its totally not water-soluble. just tried a second dose nasally and its somehow active, after some seconds even.

 

[G_Chem]

B-caryophyllene is found in many psychoactive sage species. S. Nemorosa and Salvia yangii (aka Russian Sage formerly Perovskia atriplicifolia) also contain it.

I’ve actually been smoking S. yangii flowers here again recently. The taste of the smoke is exquisite and the mild high is worth the trouble. The powdery residue though is often very potent.

-GC

 

[izo]

had a rough day today, didnt sleep. was fucked because of my neurological condition and despite of all took a little o-pce and f-pb along a little Incarvillea sinensis extract, over the day i had fun but it got a little rough as said. had some kind of strain in my head which i know from too much pb, took a little noose of the Salvia coccinea extract and in an instant it was gone. good stuff.

 

[izo]

and a very interesting taste this extract has, somewhat pleasant in the noose also. as said available on ebay for a good price. i think its ok since this is legal stuff...