Rotation of PPI Antacids, any validity to it?

[THE_REAL_OBLIVION]

I rather not take more medication than the buprenorphine and valium i'm scripted, but I got issues with stomach acidity, especially when waking up in the morning, extremely hungry so much that it hurts and i'll sometimes when brushing my teeth have reflux (I always brush my teeth before breakfast, some say it defeats the purpose,but I hate that taste you get inside your mouth when waking up, bleh), so I have to take an rx'd antacid. In the past I was on pantoprazole for 3 months, it was very meh, OTC cheap ranitidine or the one in pepcid extra strength, a dozen pills for like well, less than 7/11 hotdog and softdrink, and I would do fine with those better.

They're h2 antagonists I know, and you can get prescribed these for daily use too, but when I saw my then GP (he retired - the bastard, last september, but thats another thing) I asked for the one we had taken off the shelves (unlike the US), Cimetidine, I thought, well if it makes valium work better too... and it did but for a short time only, daily use of those 600mg horse pills of Cimetidine started feeling unhealthy after a year, I'd get these really deep feelings of balooning and pain that was hard to say where it was coming from.

So I got put on Nexium for about 8 months, it started losing its efficacy (didn't last 24 hours at all), so I asked my bupe doctor, who in the meantime is nice enough to help out with GP things knowing that I am GP-less, can I try another *prazole drug, maybe rotating them works like rotating opiates for pain does (i'm initially a pain patient...) and he said sure and I asked for the most obscure one I could find that is available in Canada, Pariet (rabeprazole) 20mg, once a day in the morning 30 minutes before eating, which is hard to accomplish, but Pariet(which is Aciphex in the US I think),doctor didn't even know about it, had to look on his small PDA with basically drugs.com's database in it) and he was sure, I never scripted it but it can't hurt and it has totally got rid of those morning stomach pains/extreme hunger that feed off each other 2 days after switching from Nexium, which is supposed to be The Best, but that's what they're saying about Dexilant now, which I almost asked for (another lets profit from an isomer of a drug which's patent is over, dexlansoprazole from lansoprazole).

So is there any logic to rotation of PPI's, or they basically all do the same effect at the same strength and last the same time in most everybody everywhere. I would doubt that some are inherently better at protecting your stomach and its linings than others. For some reason Pantoprazole is what 90% of what everyone will be scripted here for stomach issues and like I said I only used it 3 months and it wasn't very effective, H2 antagonists I could buy freely worked better.

 

[Spadez87]

I rather not take more medication than the buprenorphine and valium i'm scripted, but I got issues with stomach acidity, especially when waking up in the morning, extremely hungry so much that it hurts and i'll sometimes when brushing my teeth have reflux (I always brush my teeth before breakfast, some say it defeats the purpose,but I hate that taste you get inside your mouth when waking up, bleh), so I have to take an rx'd antacid. In the past I was on pantoprazole for 3 months, it was very meh, OTC cheap ranitidine or the one in pepcid extra strength, a dozen pills for like well, less than 7/11 hotdog and softdrink, and I would do fine with those better.

They're h2 antagonists I know, and you can get prescribed these for daily use too, but when I saw my then GP (he retired - the bastard, last september, but thats another thing) I asked for the one we had taken off the shelves (unlike the US), Cimetidine, I thought, well if it makes valium work better too... and it did but for a short time only, daily use of those 600mg horse pills of Cimetidine started feeling unhealthy after a year, I'd get these really deep feelings of balooning and pain that was hard to say where it was coming from.

So I got put on Nexium for about 8 months, it started losing its efficacy (didn't last 24 hours at all), so I asked my bupe doctor, who in the meantime is nice enough to help out with GP things knowing that I am GP-less, can I try another *prazole drug, maybe rotating them works like rotating opiates for pain does (i'm initially a pain patient...) and he said sure and I asked for the most obscure one I could find that is available in Canada, Pariet (rabeprazole) 20mg, once a day in the morning 30 minutes before eating, which is hard to accomplish, but Pariet(which is Aciphex in the US I think),doctor didn't even know about it, had to look on his small PDA with basically drugs.com's database in it) and he was sure, I never scripted it but it can't hurt and it has totally got rid of those morning stomach pains/extreme hunger that feed off each other 2 days after switching from Nexium, which is supposed to be The Best, but that's what they're saying about Dexilant now, which I almost asked for (another lets profit from an isomer of a drug which's patent is over, dexlansoprazole from lansoprazole).

So is there any logic to rotation of PPI's, or they basically all do the same effect at the same strength and last the same time in most everybody everywhere. I would doubt that some are inherently better at protecting your stomach and its linings than others. For some reason Pantoprazole is what 90% of what everyone will be scripted here for stomach issues and like I said I only used it 3 months and it wasn't very effective, H2 antagonists I could buy freely worked better.

Hey, I have acid reflux badly with Throat damage and all. I was put on pantoprazole (I'm also Canadian) and it worked pretty good but the ear nose throat doctor said it was good for only like 12 hours so more protection was needed to heal my esophagus. My point is get on something good b4 throat damage happens it sucks.

This different drug dexlansoprazole I've had zero side effects on and no GERD symptoms. I'm surprised cuz I'm extremely sensitive to Meds. If I can take I'd think most people could. I'd check it out.

Acid reflux sucks

 

[flyhighk]

I don't think rotating PPIs will help, but I suggest you try and report back. PPIs and H2 antagonists are not antacids by the way.

Have you tried antacids like calcium carbonate (tums)? Any base will do, you could even use lye (not recommended). Though their effects don't last long, and high doses in the long term are unhealthy.

 

[Foreigner]

In herbalism we consider that kind of acidity problem to be liver related, and more specifically gall bladder. In eastern medicine it's called liver fire assaulting the stomach. Being on a lot of medications doesn't help. Eat more fresh veggies, especially beet, kale, swiss chard, sprouts, and dark leafy greens. You might have some bile reflux combining with stomach acid, and the bile contains the metabolites of all those drugs in your system. Avoid greasy and excessively fatty/oily foods, they make your gallbladder excrete more bile and overnight lying vertically you might be getting some of that in your stomach. Eat more fiber, it will absorb that bile.

Include dandelion leaf in your diet, or just buy a dandelion tincture. Peppermint decoction is great for that too, but it has to be real peppermint leaves and not tea bags. Chicory, yellow dock, and turmeric (in capsules) might also work. Unpasteurized apple cider vinegar (with the mother in it) taken once a day might help too, but if it aggravates the acidity then maybe hold off on that until the heart burn is gone. You can also just drink a lot of organic apple juice daily, the malic acid content will purge the liver gently over time. (Or you can get malic acid capsules which are way more intense.)

If you just take antacids it won't solve the problem. Gotta get that liver moving.

 

[THE_REAL_OBLIVION]

Hey, I have acid reflux badly with Throat damage and all. I was put on pantoprazole (I'm also Canadian) and it worked pretty good but the ear nose throat doctor said it was good for only like 12 hours so more protection was needed to heal my esophagus. My point is get on something good b4 throat damage happens it sucks.

This different drug dexlansoprazole I've had zero side effects on and no GERD symptoms. I'm surprised cuz I'm extremely sensitive to Meds. If I can take I'd think most people could. I'd check it out.

Acid reflux sucks

That's Dexilant right? The nurse at the ORT clinic said it was "excellent" heh. I'll check it out. Pariet (rabeprazole) works ok but makes me burp a lot, which is weird for a PPI. But it kills some of the constipation I was experiencing with bupe, strangely the Nexium was increasing it, not Pariet. I'll try to talk about it to my doc next time. I was fed PPI's as part of my detox regimen. Tagamet 600mg I have used for a year straight, it worked awesome, but they kinda hesitate before rx'ing it, knowing what it does, so I got it from a walk in clinic who had no idea I was on benzos back then. But it stopped working. You actually find pantoprazole to work fine? Strange, everyone I know who has a script for reflux say it stops working fast.

@Foreigner : well you surely aren't off, it's not that I don't believe in non-rx solutions, hell, 500mg pills of magnesium glycerophosphate (one that has a high B/A unlike magnesium oxide) helps stomach issues a lot, it's just not free, unlike most rx :/
A female friend of mine had to have her gall bladder removed and her problems were reduced by massive % but have not gone away completely. I'm aware of the relationship with it all. But she was partying lots (lots of drinking). I don't drink alcohol much anymore, but I do take bupe everyday, which the ORT clinic doc has me take blood tests for liver enzyme. They're starting to wake up to the fact bupe long term isn't good for the liver, I've heard 2 girls especially going back to methadone because it was causing their liver to swell up and cause extreme pain. I only had liver pain from bupe when having more than 2-3 beers (and absolutely nothing stronger than 6% in alcohol). So it could be the bupe doing it, because the liver enzymes turned out to be fine. I did feel relief from high quality brownish apple juice from a health food store this one time too. Thanks for the tips.

 

[Dresden]

Lye (NaOH) should never be used as an antacid (from the Merck Manual). Even if it were safe at the right concentration, telling someone here to take lye for acid indigestion is extremely irresponsible, because most people are not going to have the knowledge and equipment to dilute it properly. Drinking aqueous lye will damage you beyond repair and may even kill you. Don't do it.

 

[flyhighk]

Lye (NaOH) should never be used as an antacid (from the Merck Manual). Even if it were safe at the right concentration, telling someone here to take lye for acid indigestion is extremely irresponsible, because most people are not going to have the knowledge and equipment to dilute it properly. Drinking aqueous lye will damage you beyond repair and may even kill you. Don't do it.

That's true, I said it is not recommended. I did not tell him to use it, I was just saying that in theory any base will reduce stomach acidity, and used lye as an example.