Ritalin & Vyvanse Questions

[Hugh_Myron]

Okay so I'm thinking about trying Ritalin or Vyvanse since I hate Adderall. So my question is, can you get a euphoric effect from these drugs? If so, which one would you say is better and how much should I take my first time for each one? (Adderall is not included in these questions).

 

[devintheduder]

i personally prefer adderall, but if i had to choose between the two you're suggesting i'd pick vyvanse. thats because it is more similar to addy in my opinion, both of which are more euphoric than ritalin. all IMO, but i'm pretty experienced with these RX stims.

so i think the best answer to your question would be to try them both and see what you think

 

[neversickanymore]

Lisdexamfetamine dimesylate (L-lysine-dextroamphetamine dimesylate) is a psychostimulant prodrug of the phenethylamine and amphetamine chemical classes. Its molecular structure consists of dextroamphetamine coupled with the essential amino acid L-lysine. Lisdexamfetamine itself is inactive and acts as a prodrug to dextroamphetamine upon cleavage of the lysine portion of the molecule.

http://en.wikipedia.org/wiki/Lisdexamfetamine

If you do not like the effects of adderall then its probable you may not like the effects of the Vyvanse as on of the two ingredients in adderall is dextroamphetamine

Adderall (also known as amphetamine mixed salts or variants thereof)[note 1] is a psychostimulant pharmaceutical drug of the phenethylamine class used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. The medication is a mixture of amphetamine stereoisomer salts and inactive ingredients. By salt content, the active ingredients are 75% dextroamphetamine salts[1] (the dextrorotary or "right-handed" enantiomer) and 25% levoamphetamine salts[1] (the levorotary or "left-handed" enantiomer).[note 2] Adderall is available in immediate release and extended release formulations.

http://en.wikipedia.org/wiki/Adderall


A man reason Vyvanse is formulated this way is so that people can not shoot or sniff it and get a rush.

 

[Azure Cloud]

I'd suggest not doing either if you didn't like Adderall. Ritalin always felt like dirty speed to me and vvyvanse feels a lot like Adderall but with a much longer duration. Unless you have ADD or ADHD, I don't see why you need to find an agreeable stimulant.

 

[Hugh_Myron]

I actually do have ADD but I also wanted to use them recreationally too Adderall didn't work for me recreationally or as aid for focus/concentration. I would only receive bad side.effects from it.

 

[Azure Cloud]

Supposedly some people with ADD don't get high off stimulants...I wouldn't know. But in that case I'd try ritalin if anything.

 

[Dysphoric]

Supposedly some people with ADD don't get high off stimulants...I wouldn't know. But in that case I'd try ritalin if anything.

I'm pretty sure that's a myth, I've been diagnosed with ADHD since I was 7 and got high as a kite off of 20mgs of Adderall. Methylphenidates is gross if you ask me, much more side effects and the "euphoria" (I consider more of a buzz) is very "two-dimensional". Amphetamines on the other hand are known to be the superior stimulant for catching a euphoria, but there are the odd ones who prefer DRI's, so...

 

[Azure Cloud]

I'm pretty sure that's a myth, I've been diagnosed with ADHD since I was 7 and got high as a kite off of 20mgs of Adderall. Methylphenidates is gross if you ask me, much more side effects and the "euphoria" (I consider more of a buzz) is very "two-dimensional". Amphetamines on the other hand are known to be the superior stimulant for catching a euphoria, but there are the odd ones who prefer DRI's, so...

I totally agree. I never enjoyed ritalin but I have experimented with it and did find that it definitely helped for focus. If the OP was strictly looking for a good time, I would not suggest trying it at all. But if the OP is looking for a tool for focus, he may find it with ritalin and will never know without trying it. Of course doing all this under a doctor's supervision would be best, but that is not how all of us do it (self medicate).

 

[Jabberwocky]

I actually do have ADD but I also wanted to use them recreationally too Adderall didn't work for me recreationally or as aid for focus/concentration. I would only receive bad side.effects from it.

So what you´re saying is that you would like to use a stimulant like amps for both therapeutical reasons and as a recreational drug?
I dont think that would be possible in the long term due to tolerance build up but Im basing this on things Iv read and not personal experience.
I think a lot of Amphetamine users would agree with me on this one though.

 

[crOOk]

Okay so I'm thinking about trying Ritalin or Vyvanse since I hate Adderall. So my question is, can you get a euphoric effect from these drugs? If so, which one would you say is better and how much should I take my first time for each one? (Adderall is not included in these questions).

Dissolve 20mg methylphenidate (ritalin) plus fillers in tap water, squirt it up your ass and you'll probably experience a burst of euphoria that you can currently not even imagine. You will also have the worst comedown of your life. Only iv stimulants can top this (both the comedown and the rush).
orally the ritalin isnt anything spectacular, intranasally its slightly more intense, but rectal (or iv) its otherworldly in terms of euphoria. its actually a LOT like cocaine.

My suggestion: Stop abusing your pills and take them as prescribed. The alternative would be to just forget about treating your add for now and get high instead. Don't go down that road, many have flushed their lives down the drain in a similar fashion before you. You might still be fine, but theres a good chance you wont be. There is a reason why these pills are prescribed to you.

Amphetamines on the other hand are known to be the superior stimulant for catching a euphoria, but there are the odd ones who prefer DRI's, so...

Actually, while I personally prefer amp over metylphenidate any day because of that nasty comedown, I am pretty damn sure its the other way around. most people actually claim amphetamine isnt euphoric at all for them, not even iv amphetamine is very euphoric compared to methylphenidate or cocaine.

 

[Dysphoric]

Actually, while I personally prefer amp over metylphenidate any day because of that nasty comedown, I am pretty damn sure its the other way around. most people actually claim amphetamine isnt euphoric at all for them, not even iv amphetamine is very euphoric compared to methylphenidate or cocaine.

Haha no, your observation is quite flawed. Based upon their pharmocodynamic profiles, amphetamine is much more potent then methylphenidate could ever be. There was a poll that also asked what was the best stimulant; meth/amphetamines blew crack/cocaine away. It's generally a known fact that releasing agents are much more euphoric than re-uptake inhibitors, but there are people like you who find re-uptake inhibitors more enjoyable.

 

[crOOk]

There was a poll that also asked what was the best stimulant; meth/amphetamines blew crack/cocaine away.

best stimulant != most useful/euphoric one. I wouldn't hesitate a second if you asked me which one was a more useful stimulant, but if you are asking about euphoria alone, you can not honestly claim that anyone would say amphetamine is more euphoric than cocaine.

http://www.ncbi.nlm.nih.gov/pubmed/15582920

I actually went over the study and while the results seem to indicate amphetamine coming out as a winner in terms of positive effects, it is a very close race and there are some major flaws in the study. metyhlphenidate can also produce some major dysphoria. i honestly fucking hate both methylphenidate and cocaine, but the peak euphoria ive experienced with each one is just much higher for both methylphenidate and cocaine over amphetamine which ive used daily for years.

I honestly dont have the energy to look into if and why your claims are true or false based upon the pharmacodynamics, but maybe you could point me to an article that will make this clear.

I might have exaggerated with my last sentence and you might actually be right that the majority of people finds amphetamine more euphoric than methylphenidate, but such claims arent very easy to proof and ridiculing any statement that contradicts your statements ("haha") is quite questionable imho.

also extending such observations to other substances with a similar (!) mechanism of action, as you seem to do with methylphenidate and cocaine, is plain wrong (just like its wrong to say, analogously: "dogs are bigger than cats"). if you actually claim that amphetamine produces greater euphoria than cocaine, than i really need to see some evidence for that because its plain absurd judging by all ive seen in others and experienced myself.


EDIT: I'd also like to note that i think methylphenidate is a completely different beast when iv'ed or used rectally, while ive never found that to be very impressive with amphetamine at all over administering it orally. when using both orally i would actually agree that amphetamine is the clear winner in terms of euphoria. intravenous amphetamine simply stimulates me faster, but there is no rush to it as there is with methylphenidate (or cocaine). methylphenidate is just crazy when it's iv'ed or used rectally, <its effects are really strong>.

 

[neurotic]

if you want to get high just snort 40-60mg of ritalin and you'll be kinda jittery for like 2 hours, there is a bit of euphoria to it, but imo it's a very bodily high. not worthless, still fun though.

 

[crOOk]

if you want to get high just snort 40-60mg of ritalin and you'll be kinda jittery for like 2 hours, there is a bit of euphoria to it, but imo it's a very bodily high. not worthless, still fun though.

its unbelievably more intense when you use it rectally or intravenously. snorting it is fucking useless.

 

[Dysphoric]

Maybe I should have included that the poll was based off of recreational use. Also, comparing Cocaine to d-threo-methylphenidate isn't exactly absurd at all, the "biggest" difference would be that cocaine also has serotonin re-uptake inhibition as well, but the dopamine effects are very comparable. You're the first person to argue whether amphetamines are more euphoric then methylphenidate, most everyone will vote amphetamines. Just look at their binding affinities and you'll see amphetamines takes the cake.

 

[AlphaMethylPhenyl]

amphetamine has the potential to increase dopamine by a lot more than cocaine

 

[neversickanymore]

Im totally with crook.. but even thought the euphoria of methylphenidate and coke is so very strong.. it often blows right past comfortable stage. Also I think that methylphenidate and coke manipulate the adrenals more so this can also cause people to be pretty uncomfortable. But I wonder if this adrenal manipulation is the reason orgasm is so good on these substances. Also has anyone ever used coke in combination with clonodine.. I do not know if this is safe so this is not s recommendation.. just seeing if anyone ever tried it?

Edit: I would also assume that the reason coke and methylphenidate produce such insane results when taken in certain fashion is likely to do with how fast they get through the blood brain.

 

[crOOk]

Im totally with crook.. but even thought the euphoria of methylphenidate and coke is so very strong.. it often blows right past comfortable stage. Also I think that methylphenidate and coke manipulate the adrenals more so this can also cause people to be pretty uncomfortable. But I wonder if this adrenal manipulation is the reason orgasm is so good on these substances. Also has anyone ever used coke in combination with clonodine.. I do not know if this is safe so this is not s recommendation.. just seeing if anyone ever tried it?

Edit: I would also assume that the reason coke and methylphenidate produce such insane results when taken in certain fashion is likely to do with how fast they get through the blood brain.

Oh god thank you, I was really starting to think I had been completely blind the past 15 years lol. I totally agree on both methylphenidate and cocaine being uncomfortable due to various aspects of the effects. I don't enjoy either one. Some other stimulants take this even further, especially when taken intravenously (MDPPP comes to mind, extremely euphoric, crazy compulsive)

@Dysphoric
What binding affinities exactly? They're mostly targeting different proteins, aren't they? Also, affinity != response.

 

[Alex000]

Well, I should tell you the answer really comes down to why you dislike Adderall; without knowing why, I couldn't say one to be superior over the other for you, personally. I will say, in contradiction to some other posts, Vyvanse has given me a different sort of amphetamine high than Adderall has - of course, I could feel they were both very related, they certainly have their nuances which can change the game. But, again, I don't know why you dislike Adderall, and so cannot suggest one or the other, let alone a dose, but do reply about that, and I should think I'd have a fairly certain suggestion if I knew why you don't care for it, but also your history with it, your normal dose, whether it is IR or XR, etc.

 

[Alex000]

I just read your other thread - I now have a good idea of your relationship with Adderall, which seems to be described as pretty awful, with few positive effects and many negative effects. Because of the degree to which Adderall disagreed with you, I wouldn't even recommend another amphetamine to be tried before you try something else. So, not the Vyvanse. I would suggest the Ritalin over the Vyvanse, and pretty certainly, too. If it is instant-release Ritalin, I would start with a dose of 7.5 mg to 12.5 mg (orally) or 5 mg to 10 mg (insufflated - that is, up the nose) to start, which should provide significant stimulant effect to give you an idea of the drug. For strictly therapeutic purposes, I don't think a dose of more than that would be warranted, but you want recreation, too, so I am suggesting you try what I'd consider a basic therapeutic dose for ADD to see how it goes, and if you would want and could tolerate a higher dose.